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  1. Article

    Open Access

    Prevention of activated brown adipose tissue on 18F-FDG-PET scans of young lymphoma patients: results of an ancillary study within the EuroNet-PHL-C2 trial

    Activated brown fat (aBAT) is known to affect the evaluation of 18F-FDG PET scans, especially in young patients. The aim of this study was to determine factors influencing the occurrence of aBAT, and to investiga...

    C. Pötzsch, Lars Kurch, S. Naumann, T. W. Georgi, O. Sabri… in Scientific Reports (2023)

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  2. No Access

    Article

    Favorable outcome in children and adolescents with a high proportion of advanced phase disease using single/multiple autologous or matched/mismatched allogeneic stem cell transplantations

    We determined the indication, outcome, and risk factors of single and multiple hematopoietic stem cell transplantation(s) (HSCT) in children and adolescents mostly with advanced disease. Forty-one out of 483 p...

    C. Niederwieser, S. Starke, L. Fischer, R. Krahl, J. Beck, B. Gruhn… in Annals of Hematology (2016)

  3. No Access

    Article

    Current status of FDG-PET/CT in the treatment setting of Hodgkin’s lymphoma in childhood and adolescence

    Paediatric lymphomas are rare diseases. Uniform treatment protocols are therefore important to transnationally support standardised and comparable therapy strategies. Within these protocols, FDG-PET/CT has its...

    R. Kluge, L. Kurch, T. Georgi, D. Körholz in Clinical and Translational Imaging (2015)

  4. No Access

    Article

    Sindy X — Primäre Rehabilitation bei Umkehrplastik

    Die psychologische Betreuung von krebskranken Kindern bei der Vorbereitung auf schwer wiegende Operationen (Amputation, Umkehrplastik, Endoprothese) und die postoperative Bewältigungsphase sind für die psychis...

    Prof. Dr. H. Schröder, D. Körholz, J. Al-Khazraji… in Monatsschrift Kinderheilkunde (2007)

  5. No Access

    Article

    Prognostic value of T-1 cell numbers prior to allogeneic stem cell transplantation in patients with severe graft-versus-host disease

    Assessment of risk factors for acute graft-versus-host disease (aGvHD) might help in tailoring the intensity of prophylactic immunosuppression after allogeneic stem cell transplantation (SCT), thereby decreasi...

    U Banning, T Lange, R Krahl, C Mauz-Körholz, J Krutmann… in Bone Marrow Transplantation (2005)

  6. No Access

    Chapter and Conference Paper

    Risikoadaptierte Chirurgie des Säuglingsneuroblastoms

    Zielsetzung: Das Neuroblastom ist der häufigste solide Tumor des Kindesalters. Das biologische Verhalten dieser Tumoren ist durch ein Spektrum zwischen Regression, Differenzierung und aggressivem...

    R.-B. Tröbs, D. Körholz, J. Bennek in Digitale Revolution in der Chirurgie (2002)

  7. No Access

    Article

    Glycosylated vs non-glycosylated granulocyte colony-stimulating factor (G-CSF) – results of a prospective randomised monocentre study

    The discovery of the haematopoietic growth factor granulocyte colony-stimulating factor (G-CSF) has reduced infection-related morbidity in cancer patients by alleviating post-chemotherapy neutropenia. Two form...

    H Bönig, S Silbermann, S Weller, R Kirschke, D Körholz… in Bone Marrow Transplantation (2001)

  8. No Access

    Article

    Progressive Hautveränderung bei einem Säugling

    A. E. Müller, M. Domula, S. Stephan, D. Körholz in Monatsschrift Kinderheilkunde (2001)

  9. No Access

    Article

    Immune response induced by retrovirus-mediated HSV-tk/GCV pharmacogene therapy in patients with glioblastoma multiforme

    This study was conducted to investigate immunological components of somatic gene therapy for primary glioblastoma multiforme (GBM) in adults. It involved 13 patients treated by surgical resection of tumor with...

    N G Rainov, C M Kramm, U Banning, D Riemann, H-J Holzhausen, V Heidecke… in Gene Therapy (2000)

  10. No Access

    Article

    In vivo cytokine responses to interleukin-2 immunotherapy after autologous stem cell transplantation in children with solid tumors

    The potent immunostimulatory cytokine interleukin-2 (IL-2) has been extensively investigated for its potential to induce anti-tumor immunity in a number of tumor models. Only recently the complex interplay of ...

    H Bönig, H-J Laws, A Wundes, J Verheyen, M Hannen, Y-M Kim… in Bone Marrow Transplantation (2000)

  11. No Access

    Article

    3 × 14 mg/m2 Idarubicin during induction: results of a pilot study in children with AML

    U Creutzig, D Körholz, CM Niemeyer, K Kabisch, N Graf, A Reiter… in Leukemia (2000)

  12. No Access

    Chapter and Conference Paper

    Behandlung therapierefraktärer Malignome des Kindes mittels Ganzkörper-Thermochemotherapie

    Between 1962 and 1996, nine children and adolescents were treated with whole-body hyperthermia (WBH) in combination with anticancer chemotherapy. Patients were between 2 years 10 months and 20 years old. The p...

    R.-B. Tröbs, L. Wild, Chr. Niemeyer… in Perspektiven der Chirurgie im 21. Jahrhund… (2000)

  13. No Access

    Chapter

    Lymphknoten-vergrößerungen im Kindesalter

    Bei Erwachsenen wird ein vergrößerter Lymphknoten, der sich auf eine antibiotische Behandlung hin nicht verkleinert, wegen Malignomverdachts meist direkt biopsiert. Bei Kindern können eine große Zahl unterschi...

    D. Körholz, Pro. Dr. U. Göbel in Kompendium der praktischen Medizin (2000)

  14. No Access

    Article

    Successful treatment of relapsed CML after cord blood transplantation with donor leukocyte infusion IL-2 and IFNα

    A 3-year-old girl with BCR/ABL-positive CML relapsed after related HLA-identical cord blood transplantation. She was treated with three cycles of donor lymphocyte (DLI) infusion from her 15-month-old brother. ...

    HJ Laws, W Nürnberger, D Körholz, G Kögler, J Fischer… in Bone Marrow Transplantation (2000)

  15. No Access

    Article

    DDAVP treatment in a child with von Willebrand disease type 2M

    von Willebrand disease (vWD) type 2M is characterized by the decreased platelet-dependent function of the von Willebrand factor (vWF) that is not caused by the absence of HMW vWF multimers. We report here on ...

    C. Mauz-Körholz, U. Budde, D. Körholz, U. Göbel in European Journal of Pediatrics (1999)

  16. Article

    Differential regulatory function of T-cell subsets on graft versus host and graft versus leukemia reactions after stem cell transplantation: Development of strategies for selective induction of a GvL reaction

    D Körholz, Y M Kim, T Finkensieper, B Van Kaick, U Banning… in Pediatric Research (1999)

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  17. No Access

    Article

    A classification based on T cell selection-related phenotypes identifies a subgroup of childhood T-ALL with favorable outcome in the COALL studies

    During T cell selection in the thymic cortex more than 90% of the thymocytes are eliminated by apoptosis. Based on this biology, we propose to define blasts of T cell acute lymphoblastic leukemia (ALL) with th...

    T Niehues, P Kapaun, DO Harms, S Burdach, C Kramm, D Körholz, G Janka-Schaub… in Leukemia (1999)

  18. No Access

    Chapter and Conference Paper

    Erfolgreiche rt-PA-Lysetherapie einer beidseitigen V.-subclavia-Thrombose bei asparaginaseinduzierter Hypofibrinogenämie während der Behandlung einer akuten lymphoblastischen Leukämie

    Im Rahmen der Behandlung der akuten lymphoblastischen Leukdmie im Kindesalter kommt es insbesondere bei der Anwendung von Asparaginase zu plasmatischen Gerinnungsveranderungen. Dabei wird u. a. regelmaf3ig Ant...

    C. Mauz-Körholz, J. Rübo, M. Klowik, D. Körholz… in 28. Hämophilie-Symposion Hamburg 1997 (1999)

  19. No Access

    Article

    The role of intensive AML-specific therapy in treatment of children with RAEB and RAEB-t

    To determine the role of intensive chemotherapy and allogeneic bone marrow transplantation (BMT) in treatment of refractory anemia with excess of blasts (RAEB) or RAEB-t (in transformation), the outcome of 37 ...

    U Creutzig, C Bender-Götze, J Ritter, M Zimmermann, B Stollmann-Gibbels… in Leukemia (1998)

  20. No Access

    Chapter and Conference Paper

    Elimination des hochtitrigen Faktor VIII-Hemmkörpers durch hochdosierte Faktor-VIII-Behandlung und adjuvante hochdosierte Immunglobulingabe

    Das Auftreten von Inhibitoren ist eine schwere Komplikation in der Behandlung der Hämophilie. Die Faktor(F)-VIII-Inhibitoren treten häufig bei jungen Patienten mit schwerer Hämophilie auf. Therapieziele bei di...

    C. Mauz-Körholz, H. Kruck, D. Körholz, U. Göbel in 27. Hämophilie-Symposion Hamburg 1996 (1998)

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