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Article
Open AccessPrevention of activated brown adipose tissue on 18F-FDG-PET scans of young lymphoma patients: results of an ancillary study within the EuroNet-PHL-C2 trial
Activated brown fat (aBAT) is known to affect the evaluation of 18F-FDG PET scans, especially in young patients. The aim of this study was to determine factors influencing the occurrence of aBAT, and to investiga...
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Article
Interplay of tau and functional network connectivity in progressive supranuclear palsy: a [18F]PI-2620 PET/MRI study
Progressive supranuclear palsy (PSP) is primary 4-repeat tauopathy. Evidence spanning from imaging studies indicate aberrant connectivity in PSPs. Our goal was to assess functional connectivity network alterat...
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Article
Open AccessUse of PET-CT in diagnostic workup of periprosthetic infection of hip and knee joints: significance in detecting additional infectious focus
The diagnosis and management of periprosthetic knee and hip infections as well as the identification and management of possible additional infectious foci is of great importance for successful therapy. This st...
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Article
Open AccessWhole-body [18F]-FDG-PET/MRI for staging of pediatric non-Hodgkin lymphoma: first results from a single-center evaluation
In 2015, the revised International Pediatric Non-Hodgkin Lymphoma Staging System was published. It mentions [18F]-FDG-PET/MRI as the latest method to perform whole-body imaging. However, supporting data are pendi...
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Article
Open AccessCombined PET/MRI: Global Warming—Summary Report of the 6th International Workshop on PET/MRI, March 27–29, 2017, Tübingen, Germany
The 6th annual meeting to address key issues in positron emission tomography (PET)/magnetic resonance imaging (MRI) was held again in Tübingen, Germany, from March 27 to 29, 2017. Over three days of invited pl...
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Article
Open AccessComparison of volumetric and functional parameters in simultaneous cardiac PET/MR: feasibility of volumetric assessment with residual activity from prior PET/CT
To compare cardiac left ventricular (LV) parameters in simultaneously acquired hybrid fluorine-18-fluorodeoxyglucose ([18F] FDG) positron emission tomography/magnetic resonance imaging (PET/MRI) in patients wi...
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Article
Open AccessSerotonin transporter gene promoter methylation status correlates with in vivo prefrontal 5-HTT availability and reward function in human obesity
A polymorphism in the promoter region of the human serotonin transporter (5-HTT)-coding SLC6A4 gene (5-HTTLPR) has been implicated in moderating susceptibility to stress-related psychopathology and to possess reg...
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Article
Open AccessMaternal immune activation results in complex microglial transcriptome signature in the adult offspring that is reversed by minocycline treatment
Maternal immune activation (MIA) during pregnancy has been linked to an increased risk of develo** psychiatric pathologies in later life. This link may be bridged by a defective microglial phenotype in the o...
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Article
Amyloid-Positronenemissionstomographie mit [18 F]-Florbetaben in der Demenzdiagnostik
Eine gesicherte Diagnose der Alzheimer-Krankheit beruht auf dem histologischen Nachweis von Neurofibrillen und β‑Amyloid-Ablagerungen. Amyloid-Positronenemissionstomographie (Amyloid-PET) ist eine neue diagnos...
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Article
Sex differences in serotonin–hypothalamic connections underpin a diminished sense of emotional well-being with increasing body weight
The neurobiological mechanisms linking obesity to emotional distress related to weight remain largely unknown.
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Article
Molekulare Bildgebung bei Kopf‐Hals‐Tumoren
Die 18F-Fluordesoxyglukose-Positronenemissionstomographie-Computertomographie (18F-FDG-PET-CT) hat ihren festen Stellenwert in der Diagnostik von Kopf-Hals-Tumoren. Seit einigen Jahren ist die PET-MRT als weitere...
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Article
Open AccessImpact of attenuation correction on clinical [18F]FDG brain PET in combined PET/MRI
In PET/MRI, linear photon attenuation coefficients for attenuation correction (AC) cannot be directly derived, and cortical bone is, so far, usually not considered. This results in an underestimation of the av...
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Article
The central nervous norepinephrine network links a diminished sense of emotional well-being to an increased body weight
The neurobiological mechanisms linking obesity to emotional distress remain largely undiscovered.
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Article
Combined PET/MRI: Multi-modality Multi-parametric Imaging Is Here
This paper summarises key themes and discussions from the 4th international workshop dedicated to the advancement of the technical, scientific and clinical applications of combined positron emission tomography...
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Article
Open AccessCombined PET/MR: The Real Work Has Just Started. Summary Report of the Third International Workshop on PET/MR Imaging; February 17–21, 2014, Tübingen, Germany
This paper summarises the proceedings and discussions at the third annual workshop held in Tübingen, Germany, dedicated to the advancement of the technical, scientific and clinical applications of combined PET...
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Article
Current status and future role of brain PET/MRI in clinical and research settings
Hybrid PET/MRI systematically offers a complementary combination of two modalities that has often proven itself superior to the single modality approach in the diagnostic work-up of many neurological and psych...
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Article
Initial clinical results of simultaneous 18F-FDG PET/MRI in comparison to 18F-FDG PET/CT in patients with head and neck cancer
The aim of this study was to evaluate the diagnostic capability of simultaneous 18F-fluorodeoxyglucose (FDG) positron emission tomography (PET)/MRI compared to 18F-FDG PET/CT as well as their single components in...
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Article
Metabolite analysis of [18F]Florbetaben (BAY 94-9172) in human subjects: a substudy within a proof of mechanism clinical trial
[18F]Florbetaben ([18F]BAY 94-9172) is a promising β-amyloid (Aβ) targeted PET-tracer currently in late stage clinical development. [18F]Florbetaben can assist in the more accurate diagnosis of Alzheimer’s Diseas...
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Article
18F- and 11C-labelling of quantum dots with n.c.a. [18F]fluoroethyltosylate and [11C]methyliodide: a feasibility study
Quantum dots functionalized on the outer surface with either amino- or carboxyl functions were labelled with [18F]fluoroethyltosylate and [11C]methyliodide in order to use the positron emitter-labelled fluorescen...
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Article
Open AccessIntact serotonergic and dopaminergic systems in two cases of orthostatic tremor
