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Article
Open AccessQuantum signal processing and nonlinear Fourier analysis
Elucidating a connection with nonlinear Fourier analysis (NLFA), we extend a well known algorithm in quantum signal processing (QSP) to represent measurable signals by square summable sequences. Each coefficie...
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Article
Open AccessPreoperative three-dimensional lung volumetry predicts respiratory complications in patients undergoing major liver resection for colorectal metastases
Colorectal liver metastases (CRLM) are the predominant factor limiting survival in patients with colorectal cancer and liver resection with complete tumor removal is the best treatment option for these patient...
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Article
Open AccessParaproducts for bilinear multipliers associated with convex sets
We prove bounds in the local \( L^2 \) L 2 ...
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Article
Open AccessTriglyceride cycling enables modification of stored fatty acids
Triglyceride cycling is the process of continuous degradation and re-synthesis of triglyceride in cellular stores. We show in 3T3-L1 adipocytes that triglycerides are subject to rapid turnover and re-arrangeme...
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Article
Local bounds for singular Brascamp–Lieb forms with cubical structure
We prove a range of \(L^p\) L p ...
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Chapter and Conference Paper
Singular Brascamp–Lieb: A Survey
We present an overview of results on multi-linear singular integrals in the broader context of Brascamp–Lieb inequalities. This elaborates a lecture given at the inspiring conference on Geometric Aspects of Ha...
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Article
Open AccessGeneration of immune cell containing adipose organoids for in vitro analysis of immune metabolism
Adipose tissue is an organized endocrine organ with important metabolic and immunological functions and immune cell-adipocyte crosstalk is known to drive various disease pathologies. Suitable 3D adipose tissue...
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Article
Open AccessMolecular profiling of lipid droplets inside HuH7 cells with Raman micro-spectroscopy
Raman imaging has become an attractive technology in molecular biology because of its ability to detect multiple molecular components simultaneously without labeling. Two major limitations in accurately accoun...
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Article
Multiplexed and single cell tracing of lipid metabolism
Cellular lipid metabolism is a complex network process comprising dozens of enzymes, multiple organelles and more than a thousand lipid species. Tracing metabolic reactions in this network is a major technolog...
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Article
Power-type cancellation for the simplex Hilbert transform
We prove Lp bounds for the truncated simplex Hilbert transform which grow with a power less than one of the truncation range in the logarithmic scale.
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Article
Lipschitz Linearization of the Maximal Hyperbolic Cross Multiplier
We study the linearized maximal operator associated with dilates of the hyperbolic cross multiplier in dimension two. Assuming a Lipschitz condition and a lower bound on the linearizing function, we obtain ...
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Article
No Evidence for Spontaneous Lipid Transfer at ER–PM Membrane Contact Sites
Non-vesicular lipid transport steps play a crucial role in lipid trafficking and potentially include spontaneous exchange. Since membrane contact facilitates this lipid transfer, it is most likely to occur at...
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Chapter
Globalized Design Thinking: Bridging the Gap Between Analog and Digital for Browser-Based Remote Collaboration
Remote collaboration processes require digital tools supporting work over distances. Transferring physical artifacts to the digital world and facilitating their flexible usage are common cases in remote settings.
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Article
Alterations in zinc binding capacity, free zinc levels and total serum zinc in a porcine model of sepsis
Zinc is crucial for immune function. In addition, the redistribution of zinc and other nutrients due to infection is an integral part of the host immune response to limit availability to pathogens. However, th...
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Article
Open AccessTwo different pathways of phosphatidylcholine synthesis, the Kennedy Pathway and the Lands Cycle, differentially regulate cellular triacylglycerol storage
Lipids are stored within cells in lipid droplets (LDs). They consist of a core of neutral lipids surrounded by a monolayer of phospholipids, predominantly phosphatidylcholine (PC). LDs are very dynamic and can...
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Article
Induction of the nuclear receptor PPAR-γ by the cytokine GM-CSF is critical for the differentiation of fetal monocytes into alveolar macrophages
Details of the ontogeny of alveolar macrophages remain unclear. Kopf and colleagues show that fetal monocytes give rise to alveolar macrophages in a manner dependent on the nuclear receptor PPAR-γ and the cyto...
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Article
Molecular recognition of a single sphingolipid species by a protein’s transmembrane domain
A sphingomyelin-binding motif is identified in the membrane-spanning domain of p24, a COPI machinery protein.
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Article
Open AccessOSBPL10, a novel candidate gene for high triglyceride trait in dyslipidemic Finnish subjects, regulates cellular lipid metabolism
Analysis of variants in three genes encoding oxysterol-binding protein (OSBP) homologues (OSBPL2, OSBPL9, OSBPL10) in Finnish families with familial low high-density lipoprotein (HDL) levels (N = 426) or familial...
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Article
Prominin-2 is a cholesterol-binding protein associated with apical and basolateral plasmalemmal protrusions in polarized epithelial cells and released into urine
Prominin-2 is a pentaspan membrane glycoprotein structurally related to the cholesterol-binding protein prominin-1, which is expressed in epithelial and non-epithelial cells. Although prominin-1 expression is ...
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Article
Lipoprotein particles are required for Hedgehog and Wingless signalling
Wnt and Hedgehog family proteins are secreted signalling molecules (morphogens) that act at both long and short range to control growth and patterning during development. Both proteins are covalently modified ...
