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  1. No Access

    Article

    Global profiling of SRP interaction with nascent polypeptides

    Here, the selection of substrates by the protein–RNA complex known as the signal recognition particle (SRP) is investigated in the bacterium Escherichia coli, revealing that the SRP has a strong preference for hy...

    Daniela Schibich, Felix Gloge, Ina Pöhner, Patrik Björkholm, Rebecca C. Wade… in Nature (2016)

  2. No Access

    Article

    Inhibition of Ebola virus glycoprotein-mediated cytotoxicity by targeting its transmembrane domain and cholesterol

    The high pathogenicity of the Ebola virus reflects multiple concurrent processes on infection. Among other important determinants, Ebola fusogenic glycoprotein (GP) has been associated with the detachment of i...

    Moritz Hacke, Patrik Björkholm, Andrea Hellwig, Patricia Himmels… in Nature Communications (2015)

  3. No Access

    Article

    Molecular recognition of a single sphingolipid species by a protein’s transmembrane domain

    A sphingomyelin-binding motif is identified in the membrane-spanning domain of p24, a COPI machinery protein.

    F.-Xabier Contreras, Andreas M. Ernst, Per Haberkant, Patrik Björkholm… in Nature (2012)