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Article
Open AccessInhibitory activities of selected Kampo formulations on human aldose reductase
Diabetes complications include various symptoms such as diabetic neuropathy and cognitive disorders. Aldose reductase (AR) is the rate-limiting enzyme of the polyol pathway and is one of the causal factors of ...
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Article
A frameshift variant of CYP2C8 was identified in a patient who suffered from rhabdomyolysis after administration of cerivastatin
A hypercholesterolemic patient medicated with cerivastatin for 22 days resulted in acute rhabdomyolysis. CYP2C8 and CYP3A4 are the major enzymes responsible for the metabolism of cerivastatin, and a transporte...
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Article
Lipid and fatty acid compositions of a novel docosahexaenoic acid-producing marine bacterium
An unidentified bacterial strain, SCRC-21406, isolated from the intestine of a marine fish, Glossanodon semifasciatus, produced docosahexaenoic acid at 23% (mol/mol) [=28% (w/w)] of total fatty acids in a medium ...
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Article
Incorporation of exogenous docosahexaenoic acid into various bacterial phospholipids
Incorporation of exogenous docosahexaenoic acid (DHA) into bacterial phospholipids was examined as a method for DHA-linked phospholipid production. The cultivation of 23 bacterial strains in medium with DHA sh...
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Changes in Platelet Metabolism in Contact with Hydrophilic Copolymer Surfaces
The metabolism of platelets in contact with poly(acrylamide-co-methacrylic acid) (PAAmMAc) particles was evaluated in terms of changes in cytoplasmic free calcium levels ([Ca2+]i), aderosine triphosphate (ATP) re...
