-
Article
The role of input imaging combination and ADC threshold on segmentation of acute ischemic stroke lesion using U-Net
To evaluate the effect of the weighting of input imaging combo and ADC threshold on the performance of the U-Net and to find an optimized input imaging combo and ADC threshold in segmenting acute ischemic stro...
-
Article
Open AccessImproving performance of deep learning models using 3.5D U-Net via majority voting for tooth segmentation on cone beam computed tomography
Deep learning allows automatic segmentation of teeth on cone beam computed tomography (CBCT). However, the segmentation performance of deep learning varies among different training strategies. Our aim was to p...
-
Article
Improving interobserver agreement and performance of deep learning models for segmenting acute ischemic stroke by combining DWI with optimized ADC thresholds
To examine the role of ADC threshold on agreement across observers and deep learning models (DLMs) plus segmentation performance of DLMs for acute ischemic stroke (AIS).
-
Article
Open AccessPhiladelphia chromosome-negative B-cell acute lymphoblastic leukaemia with kinase fusions in Taiwan
Philadelphia chromosome-like (Ph-like) acute lymphoblastic leukaemia (ALL), a high-risk subtype characterised by genomic alterations that activate cytokine receptor and kinase signalling, is associated with in...
-
Article
Open AccessBAFF-driven NLRP3 inflammasome activation in B cells
BAFF supports B-cell survival and homeostasis by activating the NF-κB pathway. While NF-κB is also involved in the priming signal of NLRP3 inflammasome, the role of BAFF in NLRP3 inflammasome regulation is unk...
-
Article
Open AccessFPGS relapse-specific mutations in relapsed childhood acute lymphoblastic leukemia
Although the cure rate for childhood acute lymphoblastic leukemia (ALL) has exceeded 80% with contemporary therapy, relapsed ALL remains a leading cause of cancer-related death in children. Relapse-specific mu...
-
Article
The fabrication and application of Ni-DNA nanowire-based nanoelectronic devices
DNA is a self-assembled, double stranded natural molecule that can chelate and align nickel ions between its base pairs. The fabrication of a DNA-guided nickel ion chain (Ni-DNA) device was successful, as indi...
-
Article
Open AccessExploration and characterization of the memcapacitor and memristor properties of Ni–DNA nanowire devices
A 2-μm-long Ni ion-chelated DNA molecule (Ni–DNA) was found for the first time to possess both memcapacitor and memristor properties; this Ni–DNA molecule is known as a dual memory circuit element (memelement)...
-
Article
A novel method of mining network flow to detect P2P botnets
Botnets are a serious threat to cyber-security. As a consequence, botnet detection has become an important research topic in network protection and cyber-crime prevention. P2P botnets are one of the most malic...
-
Article
Thermal stability and folding kinetics analysis of disordered protein, securin
Lacking a stable tertiary structure, intrinsically disordered proteins (IDPs) possess particular functions in cell regulation, signaling, and controlling pathways. The study of their unique structural features...
-
Article
Intraday return spillovers and its variations across trading sessions
The main purpose of this paper is to study the intraday return spillovers and their real time variations amongst selected technology stocks. Based upon randomly selected technology stocks in terms of multilate...
-
Chapter
Design of Nanodiamond Based Drug Delivery Patch for Cancer Therapeutics and Imaging Applications
The onset and recurrence of cancer is one of the major biomedical quandaries of our time. Currently, surgically removed tumors often leave behind a residual cancer cell population. As not all cancer cells can ...
-
Article
Direct Observation of Single Molecule Conformational Change of Tight-Turn Paperclip DNA Triplex in Solution
DNA triplex modulates gene expression by forming stable conformation in physiological condition. However, it is not feasible to observe this unique molecular structure of large molecule with 54 oligodeoxynucle...
-
Article
Mutation of gene required for cell spreading is corrected by serum or factor secreted by normal cells
