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    Article

    The fabrication and application of Ni-DNA nanowire-based nanoelectronic devices

    DNA is a self-assembled, double stranded natural molecule that can chelate and align nickel ions between its base pairs. The fabrication of a DNA-guided nickel ion chain (Ni-DNA) device was successful, as indi...

    Pang-Chia Chang, Chia-Yu Chang, Wen-Bin Jian, Chiun-Jye Yuan in Nano Research (2019)

  2. Article

    Open Access

    Exploration and characterization of the memcapacitor and memristor properties of Ni–DNA nanowire devices

    A 2-μm-long Ni ion-chelated DNA molecule (Ni–DNA) was found for the first time to possess both memcapacitor and memristor properties; this Ni–DNA molecule is known as a dual memory circuit element (memelement)...

    Hsueh-Liang Chu, Jian-Jhong Lai, Li-Ying Wu, Shen-Lin Chang in NPG Asia Materials (2017)

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    Article

    Development of Single-Vector Tet-on Inducible Systems with High Sensitivity to Doxycycline

    Single-vector Tet-on systems were developed to enable the tight regulation of transgenes in mammalian cells with a low dosage of doxycycline. Both the regulatory and the responsive units were integrated in a s...

    Jiun-Shuan Chao, Chun-Chieh Chao, Chu-Li Chang, Yi-Rong Chiu in Molecular Biotechnology (2012)

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    Article

    Enzyme-encapsulated silica nanoparticle for cancer chemotherapy

    A novel horseradish peroxidase-encapsulated silica nanoparticle (SNP) was generated in this study under relatively mild conditions. The generated enzyme-encapsulated SNP were relatively uniform in size (averag...

    Yi-Rong Chiu, Wei-Jen Ho, Jiun-Shuan Chao in Journal of Nanoparticle Research (2012)

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    Article

    Mammalian Ste20-like protein kinase 3 mediates trophoblast apoptosis in spontaneous delivery

    The placenta is essential in transferring gases and nutrients from the mother to the develo** fetus. Trophoblast apoptosis may cause labor or other pregnancy-related disorders. This study demonstrated the es...

    Hung-Yi Wu, Chia-Ying Lin, Tze-Yi Lin, Tai-Chang Chen, Chiun-Jye Yuan in Apoptosis (2008)

  6. No Access

    Article

    Expression, purification, characterization, and deletion mutations of phosphorylase kinase γ subunit: identification of an inhibitory domain in the γ subunit

    A catalytic fragment,γ 1-298, derived from limited chymotryptic digestion of phosphorylaseb kinase (Harris, W.R.et al., J. Biol. Chem., 265: 11740–11745, 1990), is reported to have about six-fold greater specific...

    Chi-Ying F. Huang, Chiun-Jye Yuan in Molecular and Cellular Biochemistry (1993)

  7. No Access

    Chapter

    Expression, purification, characterization, and deletion mutations of phosphorylase kinase γ subunit: identification of an inhibitory domain in the γ subunit

    A catalytic fragment, γ1–298, derived from limited chymotryptic digestion of phosphorylase b kinase (Harris, W.R. et al., J. Biol. Chem., 265: 11740–11745, 1990), is reported to have about six-fold greater specif...

    Chi-Ying F. Huang, Chiun-Jye Yuan in Reversible Protein Phosphorylation in Cell… (1993)