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Article
Temporal Trends of Inflammatory Bowel Diseases in Taiwan from 2016 to 2020: A Population-Based Study
There are scanty population-based studies investigating the incidence and prevalence rates of inflammatory bowel disease (IBD) in Taiwan.
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Article
Open AccessResistin reinforces interferon λ-3 to eliminate hepatitis C virus with fine-tuning from RETN single-nucleotide polymorphisms
The effect of resistin (RETN) on the response to anti-HCV therapy remains unclear. A prospective cohort study was performed using 655 consecutive HCV patients, of whom 513 had completed a course of interferon-...
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Article
The Trend of Inflammatory Bowel Diseases in Taiwan: A Population-Based Study
The purpose of this study was to estimate the sex- and age-specific incidence rates of inflammatory bowel diseases (IBD) in Taiwan. Site-specific cancer occurred in patients with IBD would be reported, too.
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Article
Balloon-Assisted Enteroscopy with Prophylactic Polypectomy for Peutz-Jeghers Syndrome: Experience in Taiwan
Peutz-Jeghers syndrome (PJS) is a very rare disease that often causes severe complications such as bowel obstruction or gastrointestinal tract bleeding.
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Article
Open AccessWildSpan: mining structured motifs from protein sequences
Automatic extraction of motifs from biological sequences is an important research problem in study of molecular biology. For proteins, it is desired to discover sequence motifs containing a large number of wil...
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Article
Treatment Decision for Potential Bleeders in Obscure Gastrointestinal Bleeding During Double-Balloon Enteroscopy
Double-balloon enteroscopy (DBE) is an effective tool for diagnosing and treating obscure gastrointestinal bleeding. The aim is to describe how outcomes differ with patient setting (with DBE diagnosis and inte...
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Article
Open AccessHepatic inflammation mediated by hepatitis C virus core protein is ameliorated by blocking complement activation
The pathogenesis of inflammation and fibrosis in chronic hepatitis C virus (HCV) infection remains unclear. Transgenic mice with constitutive HCV core over-expression display steatosis only. While the reasons ...
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Article
Endoscopic Treatment of Colorectal Neoplasms: A Simple and Safe Procedure to Lower the Incidence of Colorectal Cancers
Aim For many physicians who ordinarily treat patients with colonic diseases, colonoscopy is considered a prime study interest. Developments in colonoscopic equipment and methods have led to larger numbers of endo...
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Article
Open AccessIdentification of hot regions in protein-protein interactions by sequential pattern mining
Identification of protein interacting sites is an important task in computational molecular biology. As more and more protein sequences are deposited without available structural information, it is strongly de...
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Article
The Outcome Assessment of Double-Balloon Enteroscopy for Diagnosing and Managing Patients with Obscure Gastrointestinal Bleeding
Diagnosing and treating patients with obscure gastrointestinal bleeding is clinically challenging. Most lesions responsible for the origin of obscure gastrointestinal bleeding are located in the small bowel. D...
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Chapter and Conference Paper
Efficient Discovery of Structural Motifs from Protein Sequences with Combination of Flexible Intra- and Inter-block Gap Constraints
Discovering protein structural signatures directly from their primary information is a challenging task, because the residues associated with a functional motif are not necessarily clustered in one region of t...
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Article
Magnifying Endoscopy with Indigo Carmine Contrast for Differential Diagnosis of Neoplastic and Nonneoplastic Colonic Polyps
This study describes the feasibility of magnifying colonoscopy with indigo carmine dye contrast to distinguish neoplastic and nonneoplastic colonic polyps. This study sampled consecutive patients undergoing co...
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Article
Nano-sized beads and porous fiber constructs of Poly(ε-caprolactone) produced by electrospinning
Nano-sized beads and non-woven porous fiber constructs of poly(ε-caprolactone) were produced by electrospinning. Nearly spherical beads with diameters between 900 nm and 5 μm were produced with dilute solution...