33,245 Result(s)
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Chen-** Zhang
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Article
Biotic homogenisation and differentiation of fish assemblages in subtropical agroecosystems located in southern China
Anthropogenic land use has caused a major crisis to the biodiversity of stream fishes in recent decades, especially with regard to biotic homogenisation. Understanding the response of stream fishes to anthropo...
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Metal recovery from industrial solid waste by ultrasonic-assisted hydrometallurgical leaching: a review
In the context of the circular economy, there is a need for advanced methods to recover metals from industrial waste, yet classical hydrometallurgical techniques are limited. Here, we review ultrasonic-assiste...
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Methods to treat industrial salted waste: a review
The rising production of industrial salted waste induces issues of disposal and pollution, calling for advanced methods to treat, purify and recycle the raw salt in the context of the circular economy. The mai...
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Atypical phenotypes and novel OCRL variations in southern Chinese patients with Lowe syndrome
Lowe syndrome is characterized by the presence of congenital cataracts, psychomotor retardation, and dysfunctional proximal renal tubules. This study presents a case of an atypical phenotype, investigates the ...
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PAFAH2 suppresses synchronized ferroptosis to ameliorate acute kidney injury
Synchronized ferroptosis contributes to nephron loss in acute kidney injury (AKI). However, the propagation signals and the underlying mechanisms of the synchronized ferroptosis for renal tubular injury remain...
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Synthesis and pharmacological evaluation of polyamine-diarylidenyl piperidone derivatives as potent antitumor agents
Two polyamine-diarylidenyl piperidone (DAP) derivatives, dimer polyamine-H-4073 and tetrameric polyamine-H-4073, were designed and synthesized as antitumor agents by coupling the bifluoro-substituted DAP STAT3...
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Decreasing mitochondrial fission ameliorates HIF-1α-dependent pathological retinal angiogenesis
Angiogenesis plays a critical role in many pathological processes, including irreversible blindness in eye diseases such as retinopathy of prematurity. Endothelial mitochondria are dynamic organelles that unde...
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A Variance-Based Sensitivity Analysis Approach for Identifying Interactive Exposures
Chemical mixtures can significantly affect human health, but understanding the interactions among various chemical exposures and identifying influential ones in relation to some health outcomes are difficult. ...
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Acetylcytidine modification of Amotl1 by N-acetyltransferase 10 contributes to cardiac fibrotic expansion in mice after myocardial infarction
Cardiac fibrosis is a pathological scarring process that impairs cardiac function. N-acetyltransferase 10 (Nat10) is recently identified as the key enzyme for the N4-acetylcytidine (ac4C) modification of mRNAs...
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Article
Recent advances and perspectives in MXene-based cathodes for aqueous zinc-ion batteries
Aqueous zinc-ion batteries (AZIBs) show great potential for applications in grid-scale energy storage, given their intrinsic safety, cost effectiveness, environmental friendliness, and impressive electrochemic...
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Time series clustering of dynamical systems via deterministic learning
A recent deterministic learning theory has achieved locally-accurate identification of unknown system dynamics. This article presents a novel application of deterministic learning theory to unsupervised learni...
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Temperature-sensing array using the metal-to-insulator transition of NdxSm1−xNiO3
Rare-earth nickelates (RENiO3) show widely tunable metal-to-insulator transition (MIT) properties with ignorable variations in lattice constants and small latent heat across the critical temperature (TMIT). Parti...
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Airways epithelial exposure to Streptococcus pneumoniae in the presence of the alarmin IL-33 induces a novel subset of pro-inflammatory ILC2s promoting a mixed inflammatory response
We have previously shown that asthma-like airways inflammation may be induced by topical exposure to respiratory tract pathogens such as S. pneumoniae (SP) in concert with epithelial alarmins such as IL-33. Detai...
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Open AccessRadiofrequency radiation reshapes tumor immune microenvironment into antitumor phenotype in pulmonary metastatic melanoma by inducing active transformation of tumor-infiltrating CD8+ T and NK cells
Immunosuppression by the tumor microenvironment is a pivotal factor contributing to tumor progression and immunotherapy resistance. Priming the tumor immune microenvironment (TIME) has emerged as a promising s...
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Parkin deficiency promotes liver cancer metastasis by TMEFF1 transcription activation via TGF-β/Smad2/3 pathway
Parkin (PARK2) deficiency is frequently observed in various cancers and potentially promotes tumor progression. Here, we showed that Parkin expression is downregulated in liver cancer tissues, which correlates wi...
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Liquiritin inhibits TGF-β1-induced epithelial mesenchymal transition and extracellular matrix deposition in human renal proximal tubular epithelial cells by suppressing the MAPK signaling
Excessive extracellular matrix (ECM) deposition leads to renal fibrosis, a typical hallmark of chronic kidney disease. Liquiritin is a flavonoid extracted from the rhizome part of Glycyrrhiza glabra and has an...
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Article
Absence of ultrasonic-vibration-induced plasticity in metallic glacial glasses
Metallic glasses (MGs) have been found to exhibit unexpected ultrasonic-vibration-induced plasticity (UVIP), which provides a promising way to realize room temperature processing and molding of MGs. However, w...
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Transformation of A1/A2 Astrocytes Participates in Brain Ischemic Tolerance Induced by Cerebral Ischemic Preconditioning via Inhibiting NDRG2
Cerebral ischemic preconditioning (CIP) has been shown to improve brain ischemic tolerance against subsequent lethal ischemia. Reactive astrocytes play important roles in cerebral ischemia–reperfusion. Recent ...
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Article
A small-molecule activation mechanism that directly opens the KCNQ2 channel
Pharmacological activation of voltage-gated ion channels by ligands serves as the basis for therapy and mainly involves a classic gating mechanism that augments the native voltage-dependent open probability. T...
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Deleterious variants in RNF111 impair female fertility and induce premature ovarian insufficiency in humans and mice
Premature ovarian insufficiency (POI) is a heterogeneous female disorder characterized by the loss of ovarian function before the age of 40. It represents a significant detriment to female fertility. However, ...
