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  1. No Access

    Article

    A small-molecule activation mechanism that directly opens the KCNQ2 channel

    Pharmacological activation of voltage-gated ion channels by ligands serves as the basis for therapy and mainly involves a classic gating mechanism that augments the native voltage-dependent open probability. T...

    Shaoying Zhang, Demin Ma, Kun Wang, Ya Li, Zhenni Yang… in Nature Chemical Biology (2024)

  2. Article

    Open Access

    Ligand activation mechanisms of human KCNQ2 channel

    The human voltage-gated potassium channel KCNQ2/KCNQ3 carries the neuronal M-current, which helps to stabilize the membrane potential. KCNQ2 can be activated by analgesics and antiepileptic drugs but their act...

    Demin Ma, Yueming Zheng, **aoxiao Li, **aoyu Zhou, Zhenni Yang… in Nature Communications (2023)

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  3. No Access

    Article

    Transparent conductive SnO2 thin films via resonant Ta do**

    Transparent conductive oxide (TCO) thin films are highly desired as electrodes for modern flat-panel displays and solar cells. Alternative indium-free TCO materials are highly needed, because of the scarcity a...

    Vedaste Uwihoreye, Zhenni Yang, Jia-Ye Zhang, Yu-Mei Lin… in Science China Materials (2023)

  4. Article

    Open Access

    Association of body mass index and smoking on outcome of Chinese patients with colorectal cancer

    The impact of body mass index (BMI) on the prognosis of patients with colorectal cancer remains largely unknown, particularly in Asian populations. Therefore, the aim of this study was to examine the influence...

    Dan Liu, Qinggang Li, Zhenni Yang, **aocui Hu… in World Journal of Surgical Oncology (2013)

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