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Article
Intelligent Wear Condition Prediction of Ball Bearings Based on Convolutional Neural Networks and Lubricating Oil
Ball bearings play a pivotal role in rotating machinery, making it crucial to detect their wear condition in real time for preventive maintenance. This paper proposes a novel method, involving one-dimensional ...
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Article
Wear Failure Analysis of Ball Bearings with Artificial Pits for Gas Turbines
The ingression of external contaminants probably causes spalling even severe failure, which may have significant effects on operation reliability of gas turbines. To investigate the evolution and determine the...
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Article
A novel matrine derivative, WM130, inhibits activation and movement of human hepatic stellate LX-2 cells by targeting cofilin 1
Matrine, one of the active ingredients of Sophora flavescens Ait., has a protective effect in animal models on acute liver injury and liver fibrosis. However, since the protective effects are short-lived, a struc...
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Article
Open AccessPRCC reduces the sensitivity of cancer cells to DNA damage by inhibiting JNK and ATM/ATR pathways and results in a poor prognosis in hepatocellular carcinoma
The proline rich mitotic checkpoint control factor (PRCC) is involved in the splicing process of pre-mRNA. This study aims to elucidate PRCC molecular function, regulatory mechanism and diagnostic value in hep...
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Article
Open AccessKey technologies and equipment for contaminated surface/groundwater environment in the rural river network area of China: integrated remediation
To realize the integrated remediation of SW/GW and soil in the rural river network area, the integrated remediation in rural river network area project (IR-RRNA), funded by the Ministry of Science and Technolo...
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Article
Acetone adsorption capacity of sulfur-doped microporous activated carbons prepared from polythiophene
Sulfur-doped activated carbons (SACs) with high sulfur content and large specific surface area were synthesized from polythiophene for acetone removal. The sulfur content of carbons (3.10–8.43 at.%) could be t...
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Article
Open AccessCostunolide and dehydrocostuslactone combination treatment inhibit breast cancer by inducing cell cycle arrest and apoptosis through c-Myc/p53 and AKT/14-3-3 pathway
Our previous studies demonstrated that volatile oil from saussurea lappa root (VOSL), rich in two natural sesquiterpene lactones, costunolide (Cos) and dehydrocostuslactone (Dehy), exerts better anti-breast cance...
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Article
The XRCC1 Arg194Trp and Arg280His polymorphisms in head and neck cancer susceptibility: a meta-analysis
The XRCC1 Arg194Trp and Arg280His polymorphisms are likely to be implicated with the development of head and neck cancer. However, studies of association have been inconsistent. This meta-analysis of the availabl...
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Article
Anti-tumor activities of matrine and oxymatrine: literature review
Matrine (MT) and oxymatrine (OMT), two kinds of alkaloid components found in the roots of Sophora species, have various pharmacological activities and are demonstrated to have anti-inflammatory, anti-allergic,...
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Article
The association between the APE1 Asp148Glu polymorphism and breast cancer susceptibility: a meta-analysis based on case–control studies
Published data regarding the association between the APE1 Asp148Glu polymorphism and breast cancer susceptibility showed inconclusive results. This meta-analysis of literatures was performed to draw a more precis...
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Article
Rapid real-time PCR detection of transgenic cry1C rice using plasmid molecule as calibrator
Transgenic Bacillus thuringiensis (Bt) rice expressing cry1C gene showed a high level of resistance to leaffolders (Cnaphalocrocis medinalis) and stemborers. Till now, no detection method based on the plasmid mol...
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Article
Open AccessOCT4 increases BIRC5 and CCND1 expression and promotes cancer progression in hepatocellular carcinoma
OCT4 and BIRC5 are preferentially expressed in human cancer cells and mediate cancer cell survival and tumor maintenance. However, the molecular mechanism that regulates OCT4 and BIRC5 expression is not well c...
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Article
Adenovirus-Mediated Dual Gene Expression of Human Interleukin-10 and Hepatic Growth Factor Exerts Protective Effect Against CCl4-Induced Hepatocyte Injury in Rats
Hepatocyte injury is a common pathological cause of various liver diseases. Due to a lack of an effective preventive treatment, gene therapy has become an interesting approach to prevent and alleviate liver in...
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Article
Vibration reliability sensitivity analysis of general system with correlation failure modes
The vibration problem of the general system is the main object of research. The material properties and geometry of general system are random parameters because of the manufacturing environment, technical cond...
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Article
A construct-specific qualitative and quantitative PCR detection method of transgenic maize BVLA430101
Transgenic phytase maize (Zea mays L.) line BVLA430101 was the first transgenic maize obtained the security certification in 2009 in China. However, the construct of the phytase gene expre...
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Article
Integrated structure and event-specific real-time detection of transgenic cry1Ac/SCK rice Kefeng 6
Transgenic rice Kefeng 6 is a transformation event containing two insect-resistant genes, cry1Ac and SCK (modified CpTI gene) in China. In order to monitor the probable release of Kefeng 6 in the future and execu...
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Article
E2F Promoter-Regulated Oncolytic Adenovirus with p16 Gene Induces Cell Apoptosis and Exerts Antitumor Effect on Gastric Cancer