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Outcome of Extremely Preterm Infants (<1,000 g) With Congenital Heart Defects From the National Institute of Child Health and Human Development Neonatal Research Network

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  1. Article

    Pharmacokinetics and safety of a single intravenous dose of myo-inositol in preterm infants of 23–29 wk

    Myo-inositol given to preterm infants with respiratory distress has reduced death, increased survival without bronchopulmonary dysplasia, and reduced severe retinopathy of prematurity in two randomized trials. Ph...

    Dale L. Phelps, Robert M. Ward, Rick L. Williams… in Pediatric Research (2013)

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  2. Article

    Apolipoprotein E genotype and outcome in infants with hypoxic–ischemic encephalopathy

    Adults with the apolipoprotein E (APOE) gene alleles e4 and e2 are at high risk of poor neurological outcome after brain injury. The e4 allele has been associated with cerebral palsy (CP), and the e2 allele ha...

    C. Michael Cotten, Ricki F. Goldstein, Scott A. McDonald… in Pediatric Research (2014)

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  3. Article

    Open Access

    Inhaled PGE1 in neonates with hypoxemic respiratory failure: two pilot feasibility randomized clinical trials

    Inhaled nitric oxide (INO), a selective pulmonary vasodilator, has revolutionized the treatment of neonatal hypoxemic respiratory failure (NHRF). However, there is lack of sustained improvement in 30 to 46% of...

    Beena G Sood, Martin Keszler, Meena Garg, Jonathan M Klein, Robin Ohls… in Trials (2014)

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  4. Article

    Safety and pharmacokinetics of multiple dose myo-inositol in preterm infants

    Preterm infants with respiratory distress syndrome (RDS) given inositol had reduced bronchopulmonary dysplasia (BPD), death and severe retinopathy of prematurity (ROP). We assessed the safety and pharmacokinet...

    Dale L. Phelps, Robert M. Ward, Rick L. Williams, Tracy L. Nolen… in Pediatric Research (2016)

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  5. Article

    Neonatal outcomes of moderately preterm infants compared to extremely preterm infants

    Extremely preterm infants (EPT, <29 weeks’ gestation) represent only 0.9% of births in the United States; yet these infants are the focus of most published research. Moderately preterm neonates (MPT, 29–336/7 wee...

    Michele C Walsh, Edward F Bell, Sarah Kandefer, Shampa Saha… in Pediatric Research (2017)

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  6. Article

    Surgical necrotizing enterocolitis in extremely premature neonates is associated with genetic variations in an intergenic region of chromosome 8

    Twin studies suggest that genetic factors may account for up to 50% increased risk for necrotizing enterocolitis (NEC), but genome-wide association studies for NEC are lacking.

    Tamas Jilling, Namasivayam Ambalavanan, C Michael Cotten… in Pediatric Research (2018)

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  7. Article

    Prevalence and safety of diazoxide in the neonatal intensive care unit

    Diazoxide is used to treat infants with persistent hypoglycemia, but the prevalence of its use and adverse effects are not well described. We report demographic and clinical characteristics of infants treated ...

    Keyaria D. Gray, Kathryn Dudash, Carla Escobar, Colman Freel… in Journal of Perinatology (2018)

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  8. Article

    Risk of development of treated retinopathy of prematurity in very low birth weight infants

    Quantify the risk of treatment for retinopathy of prematurity (ROP) among infants meeting current U.S. screening guidelines.

    Samantha Gonski, Susan R. Hupp, C. Michael Cotten… in Journal of Perinatology (2019)

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  9. Article

    Correction: Genetic predictors of severe intraventricular hemorrhage in extremely low-birthweight infants

    An amendment to this paper has been published and can be accessed via a link at the top of the paper.

    Courtney D. Thornburg, Stephen W. Erickson, Grier P. Page… in Journal of Perinatology (2021)

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  10. Article

    Open Access

    Neuroprotective therapies in the NICU in term infants: present and future

    Outcomes of neonatal encephalopathy (NE) have improved since the widespread implementation of therapeutic hypothermia (TH) in high-resource settings. While TH for NE in term and near-term infants has proven be...

    Eleanor J. Molloy, Mohamed El-Dib, Sandra E. Juul, Manon Benders… in Pediatric Research (2023)

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  11. Article

    Open Access

    Use of term reference infants in assessing the developmental outcome of extremely preterm infants: lessons learned in a multicenter study

    Extremely preterm (EP) impairment rates are likely underestimated using the Bayley III norm-based thresholds scores and may be better assessed relative to concurrent healthy term reference (TR) infants born in...

    Charles E. Green, Jon E. Tyson, Roy J. Heyne, Susan R. Hintz… in Journal of Perinatology (2023)

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  12. Article

    Open Access

    Social distancing and extremely preterm births in the initial COVID-19 pandemic period

    Increased social distancing was associated with a lower incidence of extremely preterm live births (EPLB) during the initial COVID-19 pandemic period.

    Vivek V. Shukla, Benjamin A. Carper, Namasivayam Ambalavanan… in Journal of Perinatology (2024)

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