24 Result(s)

Article

S1-Leitlinie „Post-COVID/Long-COVID“

A. R. Koczulla, T. Ankermann, U. Behrends, P. Berlit, S. Böing, F. Brinkmann… in Der Chirurg (2022)

Article

Adiponectin promotes coxsackievirus B3 myocarditis by suppression of acute anti-viral immune responses

Adiponectin (APN) is an immunomodulatory adipocytokine that improves outcome in patients with virus-negative inflammatory cardiomyopathy and mice with autoimmune myocarditis. Here, we investigated whether APN ...

A. Jenke, L. Holzhauser, M. Löbel, K. Savvatis, S. Wilk… in Basic Research in Cardiology (2014)

Chapter

Zelluläre Immuntherapie

Im Gegensatz zu früheren Annahmen konnte inzwischen klar belegt werden, daß sich das Immunsystem bereits spontan mit Tumoren auseinandersetzt. Beim Melanom, aber auch bei anderen soliden Tumoren und Leukämien ...

U. Keilholz, L. Bergmann, M. Schmitt… in Kompendium Internistische Onkologie (2006)

Article

Reply to ‘NK cell subsets and CD107a mobilization assay’ by Zimmer et al

O Penack, C Gentilini, L Fischer, A M Asemissen, C Scheibenbogen, E Thiel… in Leukemia (2005)

Article

Wilms' tumour gene 1 (WT1) in human neoplasia

The transcription factor Wilms' tumour gene 1 (WT1) is important as a prognostic marker as well as in the detection and monitoring of minimal residual disease in leukaemia and myelodysplastic syndromes. Eviden...

U Keilholz, H D Menssen, A Gaiger, A Menke, Y Oji, Y Oka, C Scheibenbogen… in Leukemia (2005)

Article

CD56^dimCD16^neg cells are responsible for natural cytotoxicity against tumor targets

The activation of natural killer (NK) cells leads to degranulation and secretion of cytotoxic granula. During this process, the lytic granule membrane protein CD107a becomes detectable at the cell surface. Bas...

O Penack, C Gentilini, L Fischer, A M Asemissen, C Scheibenbogen, E Thiel… in Leukemia (2005)

Article

Complete remission in a patient with recurrent acute myeloid leukemia induced by vaccination with WT1 peptide in the absence of hematological or renal toxicity

V Mailänder, C Scheibenbogen, E Thiel, A Letsch, I W Blau, U Keilholz in Leukemia (2004)

Article

Aderhautmelanom Adjuvante Therapie bei Hochrisikopatienten und neue Therapieansätze im metastasierten Stadium

Die Behandlungsmodalität des primären Aderhautmelanoms hat bisher keinen direkten Einfluss auf die Überlebensprognose des Patienten. Durch die Identifizierung signifikanter Prognoseparameter bezüglich des Risi...

N. E. Bechrakis, C. Scheibenbogen, A. Schmittel, F. Servetopoulou… in Der Ophthalmologe (2002)

Chapter and Conference Paper

Phase II-Studie zur Vakzinierung von Melanompatienten mit Tyrosinase-Peptiden und GM-CSF

Melanomzellen können durch zytotoxische T-Lymphozyten (CTL) erkannt und hochspezifisch lysiert werden (siehe auch Vakzinationstherapie beim Melanom). Die Erkennung erfolgt HLA-Klasse I-abhängig in Verbindung mit ...

D. Schadendorf, U. Hofmann, A. Schmittel… in Dermatologie an der Schwelle zum neuen Jah… (2000)

Article

Detection of clonally rearranged T-cell-receptor gamma chain genes from T-cell malignancies and acute inflammatory rheumatic disease using PCR amplification, PAGE, and automated analysis

 Clonal expansions of T cells carrying identical T-cell-receptor (TCR) genes are the hallmark of T-cell malignancies, but they can also result from a strong immune reaction to a dominant epitope. The basis for...

M. Witzens, T. Möhler, M. Willhauck, C. Scheibenbogen, K.-H. Lee… in Annals of Hematology (1997)

Chapter

Cytokine-Based Treatments for Advanced Melanoma

Most patients with advanced metastatic melanoma who cannot be controlled by surgery experience rapid disease progression and die within 6-8 months. Many agents have been used for antitumor acitivity in melanom...

U. Keilholz, C. Scheibenbogen in Strategies for Immunointerventions in Dermatology (1997)

Article

Klinische Bedeutung der Cytokine IL-6, IL-8 und des C-reaktiven Proteins im Serum von Patienten mit akuter Pankreatitis

The detection of cytokines may elucidate the pathophysiological mechanisms that produce early systemic complications in acute interstitial (i) or necrotizing (n) pancreatitis (AP). The increase in the level o...

E. Stoelben, M. Nagel, D. Ockert, M. Quintel, C. Scheibenbogen, Birgit Klein… in Der Chirurg (1996)

Chapter and Conference Paper

Interleukin-2-Based Immunotherapy and Chemoimmunotherapy in Metastatic Melanoma

This report summarizes our experience in the treatment of advanced melanoma with immunotherapy and chemoimmunotherapy. A total of 45 patients initially received immunotherapy with interferon-α (IFNα) and a decres...

U. Keilholz, C. Scheibenbogen, P. Brossart… in Skin Cancer: Basic Science, Clinical Resea… (1995)

Article

Relationship between soluble tumor necrosis factor (TNF) receptors and TNFα during immunotherapy with interleukin-2 and/or interferon α

Eleven metastatic cancer patients were studied during three different regimens of immunotherapy with interleukin-2 (IL-2) and/or interferon α (IFNα): group A received 4 days of IL-2 i.a. infusion (n=3), group B I...

R. Landmann, U. Keilholz, C. Scheibenbogen… in Cancer Immunology, Immunotherapy (1994)

Chapter and Conference Paper

Adoptive Transfer of Autologous Cytotoxic Macrophages Grown from Blood Monocytes. A New Approach to Cancer Immunotherapy

Clinical trials to evaluate the potential of adoptive immunotherapy in cancer patients have been restricted to the use of lymphoid effector cells [1,2]. Of the other probably even more important host defense s...

R. Andreesen, C. Scheibenbogen, W. Brugger, G. W. Löhr in Leukemias (1993)

Chapter and Conference Paper

Multimodale Therapie des metastasierenden malignen Melanoms: Resektion residualen Tumors nach Immuntherapie mit Interleukin-2 und Interferon-α

IL-2 based immunotherapy is effective in a substantial proportion of patients with metastatic melanoma, however the duration of response is limited and benefits in survival are not proven. The resection of res...

E. Stoelben, H.-D. Saeger, C. Scheibenbogen… in Wandel der Chirurgie in unserer Zeit (1993)