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Article
Open AccessOsimertinib and anti-HER3 combination therapy engages immune dependent tumor toxicity via STING activation in trans
Over the past decade, immunotherapy delivered novel treatments for many cancer types. However, lung cancer still leads cancer mortality, and non-small-cell lung carcinoma patients with mutant EGFR cannot benef...
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Article
Aerobiology of Cupressaceae in Porto city, Portugal
In the last years, pollen-related respiratory allergies have increased worldwide. In the case of Cupressaceae pollen, allergy symptoms appearing during the winter are often confused with generic respiratory di...
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Article
Effects of microwave radiation on micro-organisms in selected materials from healthcare waste
This study confirms that microwave treatment of healthcare waste can significantly reduce the number of bacteria in a given sample. The bacterial reduction with duration of the application of radiation and the...
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Chapter and Conference Paper
Map** the Perception of Users as the Usability of Smartphones: Benchmarking Features Through the Borda Count Method
Smartphone devices are one of the products most bought by consumers and show the differential of the device in the sale may not be the only positive point, but it is also necessary to be able to keep the devic...
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Article
Magnetic susceptibility and isothermal remanent magnetization in human tissues: a study case
This study evaluated the magnetic properties, magnetic susceptibility and isothermal remanent magnetization (IRM) of tissue samples from the brain, liver, spleen, pancreas, heart and lungs, resected from huma...
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Article
ASA helps prediction of the death rate in surgical ICU patients
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Article
Lymphopenia as a predictor of bacteremia in the emergency department
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Chapter and Conference Paper
Hierarchical Modeling of Thermal Transport from Nano-to-Macroscales
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Article
Abstracts of original contributions ASNC 2004 9th annual scientific session September 3-–October 3, 2004 New York, New York
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Chapter and Conference Paper
Which Patients with Atrial Fibrillation Benefit Most from Overdrive Pacing?
A range of basically similar atrial overdrive pacing algorithms have been recently designed to prevent the onset of atrial tachyarrhythmia (AT) in patients with conventional indications for pacing [1–10]. Thes...
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Chapter
Heavy Tails, Phase Transitions, and the Nature of Cutoff
It has recently been shown that NP-complete problems exhibit “phase transitions”—narrow regions in which the computational complexity and character of solutions to these problems change abruptly. Algorithms op...
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Article
Energy Balance in Hiv Seropositive Infants 7
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Chapter
Prevalence and Antimicrobial Resistance of Campylobacter Isolates in an Industrial Poultry Unit (from Production to Slaughter) in Portugal
Campylobacter jejuni and Campylobacter coli are carried in the intestinal tract of a wide variety of wild and domestic animals, many used for food production, and constitute an unlimited source of ...
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Article
GABA turnover in mouse brain: Agreement between the rate of GABA accumulation after aminooxyacetic acid and the rate of disappearance after 3-mercaptopropionic acid
GABA levels of the whole mouse brain were studied afterin vivo inhibition of GABA synthesis by 3-mercaptopropionic acid (3-MPA, 100mg/kg i.p.) and of GABA degradation by aminooxyacetic acid (AOAA, 3.8–60 mg/ kg i...
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Article
Effects of morphine on central catecholamine turnover, blood pressure and heart rate in the rat
In the unanaesthetized rat morphine caused increased dopamine (DA) turnover, unchanged or possibly increased central noradrenaline (NA) turnover (utilization), hypertension and tachycardia. In the anaesthetize...
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Article
Gammahydroxy butyric acid: Cardiovascular effects in the rat
Gammahydroxybutyric acid (GHBA) 1 g/kg i.p. induced a marked and sustained increase in heart frequency and blood pressure in the rats. These effects of GHBA were abolished by a high spinal transection. In bioc...
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Article
Evidence for involvement of central noradrenergic neurons in the cardiovascular depression induced by morphine in the rat
Morphine caused in the anaesthetized rat reduction in brain noradrenaline (NA) turnover, hypotension and bradycardia, similarly to the antihypertensive,α-adrenergic agonist, clonidine. All effects of morphine wer...