42 Result(s)

Article

Effect of plateletcrit and methylenetetrahydrofolate reductase (MTHFR) C677T genotypes on folic acid efficacy in stroke prevention

Previous studies have shown that low platelet count combined with high plasma total homocysteine (tHcy) increased stroke risk and can be lowered by 73% with folic acid. However, the combined role of other plat...

Yuncong Shi, Zhengzhipeng Zhang, Binyan Wang… in Signal Transduction and Targeted Therapy (2024)

Article

The combined effect of MTHFR C677T and A1298C polymorphisms on the risk of digestive system cancer among a hypertensive population

The enzyme methylenetetrahydrofolate reductase (MTHFR) plays a crucial role in directing folate species towards nucleotide synthesis or DNA methylation. The MTHFR polymorphisms C677T and A1298C have been linked t...

Qiangqiang He, Ya** Wei, Hehao Zhu, Qiongyue Liang, ** Chen… in Discover Oncology (2024)

Article

The association of serum choline concentrations with the risk of cancers: a community-based nested case–control study

Few studies have been designed to investigate the effect of serum choline on the risk of incident cancer. This study aims to explore the association between serum choline and the risk of new-onset cancer. We c...

Wenqiang Li, Chong Li, Tong Liu, Yun Song, ** Chen, Lishun Liu… in Scientific Reports (2023)

Article

The association of serum betaine concentrations with the risk of new-onset cancers: results from two independent nested case-control studies

Evidence from epidemiologic studies on the association of circulating betaine levels with the incident risk of cancer has been inconsistent. We aimed to investigate the prospective association of serum betaine...

Hailun **e, Kang** Zhang, Ya** Wei, Guotian Ruan… in Nutrition & Metabolism (2023)

Article

Correction to: Geographical, Sex, Age, and Seasonal Differences in Serum Manganese Status Among Chinese Adults with Hypertension

Hong Chen, Zhixin Cui, Wenhai Lu, ** Wang, Jia Wang… in Biological Trace Element Research (2023)

Article

Positive correlation between hypertensive retinopathy and albuminuria in hypertensive adults

We investigated the association between albuminuria and hypertensive retinopathy (HR) in hypertensive adults.

Jun Li, Wenbo Zhang, Liang Zhao, **g Zhang, Haicheng She, Ying Meng… in BMC Ophthalmology (2023)

Article

Cost-effectiveness of folic acid therapy for primary prevention of stroke in patients with hypertension

For hypertensive patients without a history of stroke or myocardial infarction (MI), the China Stroke Primary Prevention Trial (CSPPT) demonstrated that treatment with enalapril-folic acid reduced the risk of ...

Tiantian Zhang, Zhuoru Liang, Tengfei Lin, David J. Cohen… in BMC Medicine (2022)

Article

Association between serum 5-methyltetrahydrofolate and homocysteine in Chinese hypertensive participants with different MTHFR C677T polymorphisms: a cross-sectional study

Clarifying the association between 5-methyltetrahydrofolate and homocysteine and the effect pattern of methylene tetrahydrofolate reductase (MTHFR C677T) may contribute to the management of homocysteine and ma...

Yu Cheng, Shuai Liu, Duo Chen, Yiman Yang, Qiongyue Liang, Ya Huo… in Nutrition Journal (2022)

Article

Association of serum choline levels and all-cause mortality risk in adults with hypertension: a nested case–control study

Serum choline levels were associated with multiple chronic diseases. However, the association between serum choline and all-cause mortality in Chinese adults with hypertension remains unclear. The purpose of t...

Mengmeng Song, Benjamin P. Xu, Qiongyue Liang, Ya** Wei… in Nutrition & Metabolism (2021)

Article

Sex difference in the association between plasma selenium and first stroke: a community-based nested case-control study

To date, there is no clearly defined association between plasma selenium levels and first stroke. We aimed to investigate the association between baseline plasma selenium and first stroke risk in a community-b...

Huan Hu, Chonglei Bi, Tengfei Lin, Lishun Liu, Yun Song… in Biology of Sex Differences (2021)

Article

Cigarette smoking and all-cause mortality in rural Chinese male adults: 15-year follow-up of the Anqing cohort study

According to the Global Burden of Disease Study 2017, smoking is one of the leading four risk factors contributing to deaths in China. We aimed to evaluate the associations of smoking with all-cause mortality ...

Li**g Ye, Jie Yang, **gyi Li, Nannan Cheng, Yue Zhang, **aofan Lu… in BMC Public Health (2021)

Article

Association of self-reported sleep duration and quality with BaPWV levels in hypertensive patients

The association between sleep conditions and arterial stiffness remains inconclusive. We aimed to investigate the relationship of sleep duration and quality with brachial-ankle pulse-wave velocity (baPWV) in h...

Huan Hu, Huan Li, **ao Huang, Huihui Bao, Yun Song, Binyan Wang… in Hypertension Research (2020)

Article

Association Between Fasting Blood Glucose and All-Cause Mortality in a Rural Chinese Population: 15-Year Follow-Up Cohort Study

The worldwide prevalence of diabetes has been increasing for decades; diabetes can lead to serious health problems and even death, but the effects of maintaining low fasting blood glucose (FBG) remain controve...

Nannan Cheng, Yue Zhang, Jie Yang, **gyi Li, Li**g Ye, Ziyi Zhou… in Diabetes Therapy (2020)