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Article
Determination and compensation of series resistances during whole-cell patch-clamp recordings using an active bridge circuit and the phase-sensitive technique
We present a technique which combines two methods in order to measure the series resistance (R S) during whole-cell patch-clamp recordings from excitable and non-excitable cells. R ...
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Article
Voltage-clamp-controlled current-clamp recordings from neurons: an electrophysiological technique enabling the detection of fast potential changes at preset holding potentials
Investigations of the properties of fast, transient potential changes (e.g. receptor potentials or synaptic potentials) in excitable cells by means of current-clamp recording techniques require the exact adjus...
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Chapter
Gap Junctions and Their Implications for Neurogenesis and Maturation of Synaptic Circuitry in the Develo** Neocortex
More and more data accumulate which provide evidence for an important role of gap junctions for the development and function of the mammalian brain. In the neocortex, gap junctions are already present at very ...
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Article
Neuronal nicotinic acetylcholine receptors and autosomal dominant nocturnal frontal lobe epilepsy: a critical review
Autosomal dominant nocturnal frontal lobe epilepsy (ADNFLE) is a distinct human epileptic syndrome. In some families, it is associated with mutations of the α4 or the β2 subunit of the neuronal nicotinic acet...
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Article
Spatial pattern of evoked synaptic excitation in the mouse neostriatum in vitro
The spatial distribution of stimulus-evoked excitation in the mouse neostriatum was investigated in vitro by using voltage-sensitive dyes and an optical multi-site recording system (laser scanning microscopy)....
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Article
Regulation of gap junction coupling in the develo** neocortex
In the develo** mammalian, neocortex gap junctions represent a transient, metabolic, and electrical communication system. These gap junctions may play a crucial role during the formation and refinement of ne...
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Article
A low-voltage activated, transient calcium current is responsible for the time-dependent depolarizing inward rectification of rat neocortical neurons in vitro
Intracellular recordings were obtained from rat neocortical neurons in vitro. The current-voltage-relationship of the neuronal membrane was investigated using current- and single-electrode-voltage-clamp techni...
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Article
Characteristics of long-duration inhibitory postsynaptic potentials in rat neocortical neuronsin vitro
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The characteristics of long-duration inhibitory postsynaptic potentials (l-IPSPs) which are evoked in rat fro...
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