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Persistent metagenomic signatures of early-life hospitalization and antibiotic treatment in the infant gut microbiota and resistome

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  1. Article

    Open Access

    Longitudinal gut virome analysis identifies specific viral signatures that precede necrotizing enterocolitis onset in preterm infants

    Necrotizing enterocolitis (NEC) is a serious consequence of preterm birth and is often associated with gut bacterial microbiome alterations. However, little is known about the development of the gut virome in ...

    Emily A. Kaelin, Cynthia Rodriguez, Carla Hall-Moore in Nature Microbiology (2022)

  2. Article

    Open Access

    Discordant transmission of bacteria and viruses from mothers to babies at birth

    The earliest microbial colonizers of the human gut can have life-long consequences for their hosts. Precisely how the neonatal gut bacterial microbiome and virome are initially populated is not well understood...

    Rabia Maqsood, Rachel Rodgers, Cynthia Rodriguez, Scott A. Handley in Microbiome (2019)

  3. Article

    Open Access

    Intestinal dysbiosis in preterm infants preceding necrotizing enterocolitis: a systematic review and meta-analysis

    Necrotizing enterocolitis (NEC) is a catastrophic disease of preterm infants, and microbial dysbiosis has been implicated in its pathogenesis. Studies evaluating the microbiome in NEC and preterm infants lack ...

    Mohan Pammi, Julia Cope, Phillip I. Tarr, Barbara B. Warner in Microbiome (2017)

  4. Article

    Open Access

    Erratum: Gut resistome development in healthy twin pairs in the first year of life

    Aimee M. Moore, Sara Ahmadi, Sanket Patel, Molly K. Gibson, Bin Wang in Microbiome (2015)

  5. Article

    Open Access

    Gut resistome development in healthy twin pairs in the first year of life

    The early life of the human host marks a critically important time for establishment of the gut microbial community, yet the developmental trajectory of gut community-encoded resistance genes (resistome) is un...

    Aimee M. Moore, Sara Ahmadi, Sanket Patel, Molly K. Gibson, Bin Wang in Microbiome (2015)