6 Result(s)
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Article
Open AccessLongitudinal gut virome analysis identifies specific viral signatures that precede necrotizing enterocolitis onset in preterm infants
Necrotizing enterocolitis (NEC) is a serious consequence of preterm birth and is often associated with gut bacterial microbiome alterations. However, little is known about the development of the gut virome in ...
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Persistent metagenomic signatures of early-life hospitalization and antibiotic treatment in the infant gut microbiota and resistome
Hospitalized preterm infants receive frequent and often prolonged exposures to antibiotics because they are vulnerable to infection. It is not known whether the short-term effects of antibiotics on the preterm...
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Article
Open AccessDeterminants of Initial Antibiotic Duration in Very Low Birth Weight Neonates
Very low birth weight (VLBW) neonates (< 1500 g) are commonly exposed to prolonged antibiotic courses related to concerns for presumed early onset sepsis often with unclear indications. While antibiotics can b...
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Infant diet and maternal gestational weight gain predict early metabolic maturation of gut microbiomes
Commensal gut bacterial communities (microbiomes) are predicted to influence human health and disease1,2. Neonatal gut microbiomes are colonized with maternal and environmental flora and mature toward a stable co...
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Article
Developmental dynamics of the preterm infant gut microbiota and antibiotic resistome
Development of the preterm infant gut microbiota is emerging as a critical research priority1. Since preterm infants almost universally receive early and often extended antibiotic therapy2, it is important to und...
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Article
Early life dynamics of the human gut virome and bacterial microbiome in infants
Colonization of the infant gut by viruses, bacteriophages and bacteria over the first two years of life.
