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  1. Article

    Open Access

    Interleukin-6 gene amplification and shortened survival in glioblastoma patients

    Interleukin-6 (IL-6) is known to promote tumour growth and survival. We evaluated IL-6 gene amplification in tumours from 53 glioma patients using fluorescence in situ hybridisation. Amplification events were det...

    A Tchirkov, T Khalil, E Chautard, K Mokhtari, L Véronèse in British Journal of Cancer (2007)

  2. Article

    Open Access

    Clinical implications of quantitative real-time RT–PCR analysis of hTERT gene expression in human gliomas

    The presence of telomerase activity in a glioma may be a predictor of its malignant potential. Activation of telomerase is regulated at the transcriptional level of the human telomerase reverse transcriptase (hTE...

    A Tchirkov, C Rolhion, J-L Kémény, B Irthum, S Puget, T Khalil in British Journal of Cancer (2003)

  3. No Access

    Chapter

    Evaluation of Stereotactic Biopsy as an aid to the Management of Supratentorial Tumors:

    The purpose of this study is to evaluate the advantages brought about by the use of stereotactic biopsies in the treatment of cerebral tumors and especially to appreciate wether the precise knowledge of the na...

    B. Irthum, J. Chazal, M. Mohr, A. M. Georget in Brain Oncology Biology, diagnosis and ther… (1987)