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Article
Open AccessInterleukin-6 gene amplification and shortened survival in glioblastoma patients
Interleukin-6 (IL-6) is known to promote tumour growth and survival. We evaluated IL-6 gene amplification in tumours from 53 glioma patients using fluorescence in situ hybridisation. Amplification events were det...
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Article
Open AccessClinical implications of quantitative real-time RT–PCR analysis of hTERT gene expression in human gliomas
The presence of telomerase activity in a glioma may be a predictor of its malignant potential. Activation of telomerase is regulated at the transcriptional level of the human telomerase reverse transcriptase (hTE...