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    Enhancing Temozolomide (TMZ) chemosensitivity using CRISPR-dCas9-mediated downregulation of O6-methylguanine DNA methyltransferase (MGMT)

    Glioblastoma (GBM) stands out as the most prevalent and aggressive intracranial tumor, notorious for its poor prognosis. The current standard-of-care for GBM patients involves surgical resection followed by ra...

    Yasamin Yousefi, Reza Nejati, Atiye Eslahi, Farzaneh Alizadeh… in Journal of Neuro-Oncology (2024)