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  1. Article

    Open Access

    ZO-1 interacts with YB-1 in endothelial cells to regulate stress granule formation during angiogenesis

    Zonula occludens-1 (ZO-1) is involved in the regulation of cell-cell junctions between endothelial cells (ECs). Here we identify the ZO-1 protein interactome and uncover ZO-1 interactions with RNA-binding prot...

    Yassine El Bakkouri, Rony Chidiac, Chantal Delisle… in Nature Communications (2024)

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  2. Article

    Open Access

    Effectiveness of implantable loop recorder and Holter electrocardiographic monitoring for the detection of arrhythmias in patients with peripartum cardiomyopathy

    Patients with peripartum cardiomyopathy (PPCM) are at increased risk of sudden cardiac death (SCD). However, the exact underlying mechanisms of SCD in PPCM remain unknown. By means of extended electrocardiogra...

    Julian Hoevelmann, Karen Sliwa, Olivia Briton… in Clinical Research in Cardiology (2023)

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  3. Article

    Open Access

    Two decades of implantable cardioverter defibrillator implantation and follow-up at a South African referral centre: trends, indications and long-term outcomes in a resource-limited setting

    More than two-thirds of cardiovascular deaths occur in low- and middle-income countries. Sudden cardiac deaths (SCD) from ventricular arrhythmias are an important cause of cardiovascular deaths. Implantable ca...

    Philasande Mkoko, Kayla Solomon, Ashley Chin in International Journal of Arrhythmia (2022)

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  4. No Access

    Protocol

    RNA Interference (RNAi) Screening in Cultured Drosophila Cells

    Genetic perturbation assays have been crucial to the discovery of molecular pathways that drive diverse biological processes. RNA interference (RNAi)-mediated depletion of gene products represents a powerful m...

    Juan-Carlos A. Padilla, Ashley Chin, Dhara Patel… in Map** Genetic Interactions (2021)

  5. No Access

    Protocol

    Puromycin Labeling Coupled with Proximity Ligation Assays to Define Sites of mRNA Translation in Drosophila Embryos and Human Cells

    Genetic mutations, whether they occur within protein-coding or noncoding regions of the genome, can affect various aspects of gene expression by influencing the complex network of intra- and intermolecular int...

    Ashley Chin, Eric Lécuyer in Map** Genetic Interactions (2021)

  6. No Access

    Protocol

    Subcellular Transcript Localization in Drosophila Embryos and Tissues Visualized by Multiplex-FISH

    Determining the spatiotemporal expression dynamics of a gene, or the subcellular localization properties of its encoded RNA, is often a key first step toward elucidating its function. Fluorescent in situ hybri...

    Julie Bergalet, Carole Iampietro, Ashley Chin… in In Situ Hybridization Methods (2015)

  7. No Access

    Article

    Characterisation of peripartum cardiomyopathy by cardiac magnetic resonance imaging

    Ntobeko B. A. Ntusi, Ashley Chin in European Radiology (2009)