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Article
Open AccessStrategies for enhancing the representation of women in clinical trials: an evidence map
Equitable sex- and gender-based representation in clinical trials is an essential step to ensuring evidence-based care for women. While multi-institutional actions have led to significant improvements in the i...
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Article
Bioinoculants: the agrarian avengers
Bioinoculants are beneficial microorganisms that are used in agriculture to enhance plant growth and productivity, improve soil health, and reduce the use of chemical fertilizers and pesticides. They include b...
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Article
Open AccessIn vitro, in vivo, and in silico analysis of synbiotics as preventive interventions for lipid metabolism in ethanol-induced adipose tissue injury
The risk of alcoholic liver disease (ALD) is increased by excessive ethanol drinking. For the prevention of ALD, the effects of ethanol on the liver, adipose tissue, and gut are crucial. Interestingly, garlic ...
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Article
Traversing through the intricate interplay of plant microbiome front runners
Bacteria produce a plethora of metabolites and substances, both intra- and extra- cellular, that govern the diversity as well as keystone functionalities in its close vicinity. A special group of bacteria, pla...
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Article
Carcinoma Cervix with Delayed Occurrence of Solitary Lung Metastasis Resenting as Pancoast Tumor, A Case Report
Cervical carcinoma is 4th most commonly occurring malignancy in women worldwide. The most common site of metastasis is lung via hematogenous route. Among cervical cancer patients, most frequently occurring sec...
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Article
Alterations in bone metabolites with age in C57BL/6 mice model
Understanding the pathophysiology behind age-related diseases is an urgent need as the elderly population continues to grow. With age, there is a high risk of musculoskeletal deterioration and associated morbi...
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Article
CRISPR: The Multidrug Resistance Endgame?
The flexibility of microbes to undergo or adapt to the changes in their physiology and genotypical traits has enabled the microbes acquiring resistance to latest or recently discovered drugs which have consequ...
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Protocol
RNA Interference (RNAi) Screening in Cultured Drosophila Cells
Genetic perturbation assays have been crucial to the discovery of molecular pathways that drive diverse biological processes. RNA interference (RNAi)-mediated depletion of gene products represents a powerful m...
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Article
Mindfulness and ADHD (Attention Deficit Hyperactivity Disorder) in Adolescents
The aim of this review is to discuss benefits of mindfulness for the treatment of attention deficit hyperactivity disorder (ADHD) in adolescents.
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Article
Attention Deficit Hyperactivity Disorder and Its Treatment in Geriatrics
The main purpose of this review is to understand how attention deficit hyperactivity disorder (ADHD) affects geriatrics (elderly population).
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Article
Driving and Road Rage Associated with Attention Deficit Hyperactivity Disorder (ADHD): a Systematic Review
The main objective of the present review was to give an overall idea regarding the impacts of ADHD on driving and road rage. In addition, we have also discussed the possible treatment options for ADHD drivers ...
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Chapter
Redox Mechanisms Influencing cGMP Signaling in Pulmonary Vascular Physiology and Pathophysiology
The soluble form of guanylate cyclase (sGC) and cGMP signaling are major regulators of pulmonary vasodilation and vascular remodeling that protect the pulmonary circulation from hypertension development. Nitri...
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Article
A Solution State Study of the Complexation and Thermodynamic Parameters of Binary Complexes of the Inner Transition Metals with Piracetam in Aqueous and Mixed Solvents
An equilibrium study on complexation behavior of the inner transition metals, where M = {Y(III), La(III, Ce(III, Pr(III), Nd(III), Sm(III), Gd(III), Dy(III), Th(IV)} and L = piracetam, has been carried out usi...
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Chapter
Rhizobacteria for Management of Nematode Disease in Plants
Plant-parasitic nematodes are considered worst enemies of mankind because of devastation they cause to crops. There is hardly any crop which is not affected by nematodes. Management of the nematode disease app...
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Article
Decreased Sensory Responses in Osteocalcin Null Mutant Mice Imply Neuropeptide Function
Osteocalcin, the most abundant member of the family of extracellular mineral binding gamma-carboxyglutamic acid proteins is synthesized primarily by osteoblasts. Its affinity for calcium ions is believed to li...
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Article
Growth Enhancement of Chickpea in Saline Soils Using Plant Growth-Promoting Rhizobacteria
Bacterial isolates with the ability to tolerate salinity and plant growth-promoting features were isolated from the saline areas of Gujarat, India, that is, Bhavnagar and Khambat. A total of 176 strains of rhi...
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Article
Open AccessExtracellular Superoxide Dismutase Overexpression Can Reverse the Course of Hypoxia-Induced Pulmonary Hypertension
Hypoxia leads to free radical production, which has a pivotal role in the pathophysiology of pulmonary hypertension (PH). We hypothesized that treatment with extracellular superoxide dismutase (EC-SOD) could a...
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Chapter
Nutrient Availability and Management in the Rhizosphere by Microorganisms
Crop nutrition is frequently inadequate as a result of the expansion of crop** into marginal lands, elevated crop yields placing increasing demands on soil nutrient reserves, and environmental and economic c...
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Article
Ab-IL2 fusion proteins mediate NK cell immune synapse formation by polarizing CD25 to the target cell-effector cell interface
The huKS-IL2 immunocytokine (IC) consists of IL2 fused to a mAb against EpCAM, while the hu14.18-IL2 IC recognizes the GD2 disialoganglioside. They are under evaluation for treatment of EpCAM+ (ovarian) and GD2+ ...
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Article
Open AccessRedox regulation of responses to hypoxia and NO-cGMP signaling in pulmonary vascular pathophysiology