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  1. Article

    Open Access

    An Integrative multi-lineage model of variation in leukopoiesis and acute myelogenous leukemia

    Acute myelogenous leukemia (AML) progresses uniquely in each patient. However, patients are typically treated with the same types of chemotherapy, despite biological differences that lead to differential respo...

    Joyatee M. Sarker, Serena M. Pearce, Robert P. Nelson Jr. in BMC Systems Biology (2017)

  2. No Access

    Reference Work Entry In depth

    Applied Control Theory for Biological Processes

    Sarah L. Noble, Ann E. Rundell in Encyclopedia of Applied and Computational Mathematics (2015)

  3. No Access

    Article

    Experimental Design for Dynamics Identification of Cellular Processes

    We address the problem of using nonlinear models to design experiments to characterize the dynamics of cellular processes by using the approach of the Maximally Informative Next Experiment (MINE), which was in...

    Vu Dinh, Ann E. Rundell, Gregery T. Buzzard in Bulletin of Mathematical Biology (2014)

  4. No Access

    Article

    A Global Parallel Model Based Design of Experiments Method to Minimize Model Output Uncertainty

    Model-based experiment design specifies the data to be collected that will most effectively characterize the biological system under study. Existing model-based design of experiment algorithms have primarily r...

    Jason N. Bazil, Gregory T. Buzzard, Ann E. Rundell in Bulletin of Mathematical Biology (2012)

  5. No Access

    Article

    Ischemia’s Proliferative and Morphological Effects: Analyzing the Roles of Hypoxia, Hypercapnia, and Glucose

    In ischemic tissues, oxygen (O2) and glucose become depleted while cells concomitantly promote carbon dioxide (CO2) and waste accumulation. Hypoxia has become a topic of great interest. Notably, these insults, in...

    Alissa L. Russ, David E. Anderson, Jason J. McGill in Cellular and Molecular Bioengineering (2010)

  6. No Access

    Article

    Investigating the Role of Ischemia vs. Elevated Hydrostatic Pressure Associated with Acute Obstructive Uropathy

    Obstructive uropathy can cause irreversible renal damage. It has been hypothesized that elevated hydrostatic pressure within renal tubules and/or renal ischemia contributes to cellular injury following obstruc...

    Alissa L. Russ, Iunia A. Dadarlat, Karen M. Haberstroh in Annals of Biomedical Engineering (2009)

  7. Article

    Open Access

    SBML-SAT: a systems biology markup language (SBML) based sensitivity analysis tool

    It has long been recognized that sensitivity analysis plays a key role in modeling and analyzing cellular and biochemical processes. Systems biology markup language (SBML) has become a well-known platform for ...

    Zhike Zi, Yanan Zheng, Ann E Rundell, Edda Klipp in BMC Bioinformatics (2008)