39 Result(s)
within
Anil K. Sood
Cancer Research
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Article
Open AccessEnhanced plant-derived vesicles for nucleotide delivery for cancer therapy
Small RNAs (microRNAs [miRNAs] or small interfering RNAs [siRNAs]) are effective tools for cancer therapy, but many of the existing carriers for their delivery are limited by low bioavailability, insufficient ...
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Article
Open AccessIn situ profiling reveals metabolic alterations in the tumor microenvironment of ovarian cancer after chemotherapy
In this study, we investigated the metabolic alterations associated with clinical response to chemotherapy in patients with ovarian cancer. Pre- and post-neoadjuvant chemotherapy (NACT) tissues from patients w...
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Article
Open AccessTargeting CCR2+ macrophages with BET inhibitor overcomes adaptive resistance to anti-VEGF therapy in ovarian cancer
Tumor-associated macrophages (TAMs) are known to contribute to adaptive resistance to anti-vascular endothelial growth factor (VEGF) antibody (AVA) therapy in ovarian cancer. BET (bromodomain and extra-termina...
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Article
Of vascular defense, hemostasis, cancer, and platelet biology: an evolutionary perspective
We have established considerable expertise in studying the role of platelets in cancer biology. From this expertise, we were keen to recognize the numerous venous-, arterial-, microvascular-, and macrovascular...
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Article
Author Correction: Chronic stress promotes tumor growth and angiogenesis in a mouse model of ovarian carcinoma
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Article
Immune microenvironment composition in high-grade serous ovarian cancers based on BRCA mutational status
An in-depth analysis of the tumor microenvironment of ovarian cancer is needed. The purpose of this study was to elucidate the architecture of the immune microenvironment of high-grade serous ovarian cancers (...
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Article
Open AccessCD8+ T cells inhibit metastasis and CXCL4 regulates its function
The mechanism by which immune cells regulate metastasis is unclear. Understanding the role of immune cells in metastasis will guide the development of treatments improving patient survival.
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Chapter
The Roles of Anoikis in Cervical Cancer
Cervical cancer is one of the most common malignancies in women worldwide. Tumor invasion and distant metastasis are among the main reasons for mortality in patients with cervical cancer. Resistance to anoikis...
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Article
Stress, inflammation, and eicosanoids: an emerging perspective
Clinical and experimental studies support the notion that adrenergic stimulation and chronic stress affect inflammation, metabolism, and tumor growth. Eicosanoids are also known to heavily influence inflammati...
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Article
Bioactive lipid metabolism in platelet “first responder” and cancer biology
Platelets can serve as “first responders” in cancer and metastasis. This is partly due to bioactive lipid metabolism that drives both platelet and cancer biology. The two primary eicosanoid metabolites that ma...
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Article
RNA interference-based therapy and its delivery systems
RNA interference (RNAi) is considered a highly specific approach for gene silencing and holds tremendous potential for treatment of various pathologic conditions such as cardiovascular diseases, viral infectio...
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Article
Open AccessErratum to: MIIP remodels Rac1-mediated cytoskeleton structure in suppression of endometrial cancer metastasis
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Article
Open AccessImmune cell profiling in cancer: molecular approaches to cell-specific identification
The immune system has many important regulatory roles in cancer development and progression. Given the emergence of effective immune therapies against many cancers, reliable predictors of response are needed. ...
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Article
Platelet “first responders” in wound response, cancer, and metastasis
Platelets serve as “first responders” during normal wounding and homeostasis. Arising from bone marrow stem cell lineage megakaryocytes, anucleate platelets can influence inflammation and immune regulation. Bi...
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Article
Open AccessEndothelial cell malignancies: new insights from the laboratory and clinic
Endothelial cell malignancies are rare in the Western world and range from intermediate grade hemangioendothelioma to Kaposi sarcoma to aggressive high-grade angiosarcoma that metastasize early and have a high...
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Reference Work Entry In depth
Ovarian Cancer Hormonal Therapy
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Article
Open AccessMIIP remodels Rac1-mediated cytoskeleton structure in suppression of endometrial cancer metastasis
Endometrial carcinoma (EC) is one of the most common malignancies of the female reproductive system. Migration and invasion inhibitory protein (MIIP) gene was recently discovered candidate tumor suppress gene ...
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Article
Ovarian cancer
Ovarian cancer is not a single disease and can be subdivided into at least five different histological subtypes that have different identifiable risk factors, cells of origin, molecular compositions, clinical ...
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Article
A prospective study of phobic anxiety, risk of ovarian cancer, and survival among patients
In ovarian cancer patients and mouse models, psychosocial stress is associated with higher circulating markers of angiogenesis and cell migration, impaired immune response, and increasing tumor burden and aggr...
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Article
Rethinking ovarian cancer II: reducing mortality from high-grade serous ovarian cancer
This Opinion article outlines a set of research priorities, based on discussions held at the 2015 Helene Harris Memorial Trust Ovarian Cancer Action meeting, that the authors believe will reduce incidence and ...
