Lernen in Standardisierungsprozessen
Eine Analyse der Etablierung technologischer Innovationen im Markt
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Open AccessQuantitative live cell imaging of a tauopathy model enables the identification of a polypharmacological drug candidate that restores physiological microtubule interaction
Tauopathies such as Alzheimer’s disease are characterized by aggregation and increased phosphorylation of the microtubule-associated protein tau. Tau’s pathological changes are closely linked to neurodegenerat...
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Inhibition of Ebola virus glycoprotein-mediated cytotoxicity by targeting its transmembrane domain and cholesterol
The high pathogenicity of the Ebola virus reflects multiple concurrent processes on infection. Among other important determinants, Ebola fusogenic glycoprotein (GP) has been associated with the detachment of i...
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Open AccessProliferation and cilia dynamics in neural stem cells prospectively isolated from the SEZ
Neural stem cells (NSCs) generate new neurons in vivo and in vitro throughout adulthood and therefore are physiologically and clinically relevant. Unveiling the mechanisms regulating the lineage progression from ...
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Innovationen durch Kundenintegration bei unternehmensbezogenen Dienstleistungen
Innovationen gelten seit jeher als zentrale Antriebskraft für Unternehmenserfolg sowie für wirtschaftliches und gesellschaftliches Wachstum. Im Zuge einer tiefgreifenden Veränderung der Struktur und Dynamik de...
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AN2, the mouse homologue of NG2, is a surface antigen on glial precursor cells implicated in control of cell migration
Molecular studies have demonstrated that the murine AN2 antigen is the mouse homologue of the rat NG2 and human MCSP protein. The molecule is a single-pass transmembrane protein which carries a variable number...
