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  1. Article

    Open Access

    Advancing translational research with the Semantic Web

    A fundamental goal of the U.S. National Institute of Health (NIH) "Roadmap" is to strengthen Translational Research, defined as the movement of discoveries in basic research to application at the clinical level. ...

    Alan Ruttenberg, Tim Clark, William Bug, Matthias Samwald in BMC Bioinformatics (2007)

  2. No Access

    Article

    The OBO Foundry: coordinated evolution of ontologies to support biomedical data integration

    The value of any kind of data is greatly enhanced when it exists in a form that allows it to be integrated with other data. One approach to integration is through the annotation of multiple bodies of data usin...

    Barry Smith, Michael Ashburner, Cornelius Rosse, Jonathan Bard in Nature Biotechnology (2007)

  3. Article

    Open Access

    Modeling biomedical experimental processes with OBI

    Experimental descriptions are typically stored as free text without using standardized terminology, creating challenges in comparison, reproduction and analysis. These difficulties impose limitations on data e...

    Ryan R Brinkman, Mélanie Courtot, Dirk Derom in Journal of Biomedical Semantics (2010)

  4. Article

    Open Access

    The representation of protein complexes in the Protein Ontology (PRO)

    Representing species-specific proteins and protein complexes in ontologies that are both human- and machine-readable facilitates the retrieval, analysis, and interpretation of genome-scale data sets. Although ...

    Carol J Bult, Harold J Drabkin, Alexei Evsikov, Darren Natale in BMC Bioinformatics (2011)

  5. Article

    Open Access

    The neurological disease ontology

    We are develo** the Neurological Disease Ontology (ND) to provide a framework to enable representation of aspects of neurological diseases that are relevant to their treatment and study. ND is a representati...

    Mark Jensen, Alexander P Cox, Naveed Chaudhry, Marcus Ng in Journal of Biomedical Semantics (2013)

  6. Article

    Open Access

    The Non-Coding RNA Ontology (NCRO): a comprehensive resource for the unification of non-coding RNA biology

    In recent years, sequencing technologies have enabled the identification of a wide range of non-coding RNAs (ncRNAs). Unfortunately, annotation and integration of ncRNA data has lagged behind their identificat...

    **gshan Huang, Karen Eilbeck, Barry Smith in Journal of Biomedical Semantics (2016)

  7. Article

    Open Access

    OmniSearch: a semantic search system based on the Ontology for MIcroRNA Target (OMIT) for microRNA-target gene interaction data

    As a special class of non-coding RNAs (ncRNAs), microRNAs (miRNAs) perform important roles in numerous biological and pathological processes. The realization of miRNA functions depends largely on how miRNAs re...

    **gshan Huang, Fernando Gutierrez, Harrison J. Strachan in Journal of Biomedical Semantics (2016)

  8. Article

    Open Access

    The Cell Ontology 2016: enhanced content, modularization, and ontology interoperability

    The Cell Ontology (CL) is an OBO Foundry candidate ontology covering the domain of canonical, natural biological cell types. Since its inception in 2005, the CL has undergone multiple rounds of revision and ex...

    Alexander D. Diehl, Terrence F. Meehan in Journal of Biomedical Semantics (2016)

  9. Article

    Open Access

    Structuring, reuse and analysis of electronic dental data using the Oral Health and Disease Ontology

    A key challenge for improving the quality of health care is to be able to use a common framework to work with patient information acquired in any of the health and life science disciplines. Patient information...

    William D. Duncan, Thankam Thyvalikakath in Journal of Biomedical Semantics (2020)

  10. No Access

    Article

    MRIO: the Magnetic Resonance Imaging Acquisition and Analysis Ontology

    Magnetic resonance imaging of the brain is a useful tool in both the clinic and research settings, aiding in the diagnosis and treatments of neurological disease and expanding our knowledge of the brain. Howev...

    Alexander Bartnik, Lucas M. Serra, Mackenzie Smith, William D. Duncan in Neuroinformatics (2024)