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Chapter
The Foundational Model of Anatomy Ontology
Anatomy is the structure of biological organisms. The term also denotes the scientific discipline devoted to the study of anatomical entities and the structural and developmental relations that obtain among th...
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Article
The OBO Foundry: coordinated evolution of ontologies to support biomedical data integration
The value of any kind of data is greatly enhanced when it exists in a form that allows it to be integrated with other data. One approach to integration is through the annotation of multiple bodies of data usin...
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Article
Open AccessRelations in biomedical ontologies
To enhance the treatment of relations in biomedical ontologies we advance a methodology for providing consistent and unambiguous formal definitions of the relational expressions used in such ontologies in a wa...
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Chapter and Conference Paper
Anatomical Information Science
The Foundational Model of Anatomy (FMA) is a map of the human body. Like maps of other sorts – including the map-like representations we find in familiar anatomical atlases – it is a representation of a certai...
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Article
Deficiency in cells expressing terminal transferase in autoimmune (motheaten) mice
The extensive breakdown of immune homeostasis in the motheaten mouse (me/me) has been ascribed to a single gene defect on chromosome 6 (ref. 1). These mice develop skin lesions within the first week of life, do n...
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Chapter
A Quantitative Assessment of Cellular Recovery in Lymphoid Tissue
Measurement of cellular responses in quantitative terms is an essential requisite for elucidating the basic processes of hemopoiesis under normal physiological conditions as Well as under conditions of specifi...
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Article
Two Morphologically and Kinetically Distinct Populations of Lymphoid Cells in the Bone Marrow
LYMPHOID cells account for 20–30 per cent of all nucleated cells in the bone marrow of common laboratory animals and in the human foetus. Evidence from a number of sources suggests that bone marrow lymphocytes...