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  1. No Access

    Article

    MRIO: the Magnetic Resonance Imaging Acquisition and Analysis Ontology

    Magnetic resonance imaging of the brain is a useful tool in both the clinic and research settings, aiding in the diagnosis and treatments of neurological disease and expanding our knowledge of the brain. Howev...

    Alexander Bartnik, Lucas M. Serra, Mackenzie Smith, William D. Duncan in Neuroinformatics (2024)

  2. Article

    Open Access

    Structuring, reuse and analysis of electronic dental data using the Oral Health and Disease Ontology

    A key challenge for improving the quality of health care is to be able to use a common framework to work with patient information acquired in any of the health and life science disciplines. Patient information...

    William D. Duncan, Thankam Thyvalikakath in Journal of Biomedical Semantics (2020)

  3. Article

    Open Access

    The Cell Ontology 2016: enhanced content, modularization, and ontology interoperability

    The Cell Ontology (CL) is an OBO Foundry candidate ontology covering the domain of canonical, natural biological cell types. Since its inception in 2005, the CL has undergone multiple rounds of revision and ex...

    Alexander D. Diehl, Terrence F. Meehan in Journal of Biomedical Semantics (2016)

  4. Article

    Open Access

    OmniSearch: a semantic search system based on the Ontology for MIcroRNA Target (OMIT) for microRNA-target gene interaction data

    As a special class of non-coding RNAs (ncRNAs), microRNAs (miRNAs) perform important roles in numerous biological and pathological processes. The realization of miRNA functions depends largely on how miRNAs re...

    **gshan Huang, Fernando Gutierrez, Harrison J. Strachan in Journal of Biomedical Semantics (2016)

  5. Article

    Open Access

    The Non-Coding RNA Ontology (NCRO): a comprehensive resource for the unification of non-coding RNA biology

    In recent years, sequencing technologies have enabled the identification of a wide range of non-coding RNAs (ncRNAs). Unfortunately, annotation and integration of ncRNA data has lagged behind their identificat...

    **gshan Huang, Karen Eilbeck, Barry Smith in Journal of Biomedical Semantics (2016)

  6. Article

    Open Access

    The neurological disease ontology

    We are develo** the Neurological Disease Ontology (ND) to provide a framework to enable representation of aspects of neurological diseases that are relevant to their treatment and study. ND is a representati...

    Mark Jensen, Alexander P Cox, Naveed Chaudhry, Marcus Ng in Journal of Biomedical Semantics (2013)

  7. Article

    Open Access

    The representation of protein complexes in the Protein Ontology (PRO)

    Representing species-specific proteins and protein complexes in ontologies that are both human- and machine-readable facilitates the retrieval, analysis, and interpretation of genome-scale data sets. Although ...

    Carol J Bult, Harold J Drabkin, Alexei Evsikov, Darren Natale in BMC Bioinformatics (2011)

  8. Article

    Open Access

    Meeting Report: BioSharing at ISMB 2010

    This report summarizes the proceedings of the one day BioSharing meeting held at the Intelligent Systems for Molecular Biology (ISMB) 2010 conference in Boston, MA, USA This inaugural BioSharing event was host...

    Dawn Field, Susanna Sansone, Edward F. DeLong, Peter Sterk in Standards in Genomic Sciences (2010)

  9. Article

    Open Access

    Modeling biomedical experimental processes with OBI

    Experimental descriptions are typically stored as free text without using standardized terminology, creating challenges in comparison, reproduction and analysis. These difficulties impose limitations on data e...

    Ryan R Brinkman, Mélanie Courtot, Dirk Derom in Journal of Biomedical Semantics (2010)

  10. Article

    Open Access

    OntoFox: web-based support for ontology reuse

    Ontology development is a rapidly growing area of research, especially in the life sciences domain. To promote collaboration and interoperability between different projects, the OBO Foundry principles require ...

    Zuoshuang **ang, Mélanie Courtot, Ryan R Brinkman, Alan Ruttenberg in BMC Research Notes (2010)

  11. Chapter and Conference Paper

    Simplifying Access to Large-Scale Health Care and Life Sciences Datasets

    Within the health care and life sciences (HCLS) domain, a plethora of phenomena exists that range across the whole “vertical scale” of biomedicine. To accurately research and describe those phenomena, a tremen...

    Holger Stenzhorn, Kavitha Srinivas in The Semantic Web: Research and Applications (2008)

  12. No Access

    Article

    The OBO Foundry: coordinated evolution of ontologies to support biomedical data integration

    The value of any kind of data is greatly enhanced when it exists in a form that allows it to be integrated with other data. One approach to integration is through the annotation of multiple bodies of data usin...

    Barry Smith, Michael Ashburner, Cornelius Rosse, Jonathan Bard in Nature Biotechnology (2007)

  13. Article

    Open Access

    Advancing translational research with the Semantic Web

    A fundamental goal of the U.S. National Institute of Health (NIH) "Roadmap" is to strengthen Translational Research, defined as the movement of discoveries in basic research to application at the clinical level. ...

    Alan Ruttenberg, Tim Clark, William Bug, Matthias Samwald in BMC Bioinformatics (2007)

  14. No Access

    Chapter and Conference Paper

    Connectedness Profiles in Protein Networks for the Analysis of Gene Expression Data

    Knowledge about protein function is often encoded in the form of large and sparse undirected graphs where vertices are proteins and edges represent their functional relationships. One elementary task in the co...

    Joël Pradines, Vlado Dančík, Alan Ruttenberg in Research in Computational Molecular Biology (2007)