24 Result(s)

Article

Addressing sex and gender to improve asthma management

Sex (whether one is ‘male’ or ‘female’, based on biological characteristics) and gender (defined by socially constructed roles and behaviors) influence asthma diagnosis and management. For example, women gener...

Louis-Philippe Boulet, Kim L. Lavoie… in npj Primary Care Respiratory Medicine (2022)

Article

Clarifying SABA overuse: Translating Canadian Thoracic Society guidelines into clinical practice

Patients with asthma frequently over rely on short-acting beta-agonists (SABA) to treat acute symptoms. This can adversely impact quality of life and increase the risk of exacerbations. SABA overuse is also as...

Anne K. Ellis, Vanessa Foran, Alan Kaplan… in Allergy, Asthma & Clinical Immunology (2022)

Article

Pulmonary Therapy Podcast—COVID-19: Research and Real-World Experiences from the Editorial Board

The Editorial Board have prepared a podcast describing their experiences over the past year of the COVID-19 pandemic. The Editorial Board describe how COVID-19 impacted their research and how the initial clini...

Kai Michael Beeh, Nazia Chaudhuri, Timothy J. Craig, Alan Kaplan… in Pulmonary Therapy (2021)

Article

The Myth of Mild: Severe Exacerbations in Mild Asthma: An Underappreciated, but Preventable Problem

Asthma is a common, chronic inflammatory airway disease, characterised by unpredictable episodes of worsening symptoms, or exacerbations. Causes of asthma exacerbations include viral infections, exposure to al...

Alan Kaplan in Advances in Therapy (2021)

Article

A call to action for improving clinical outcomes in patients with asthma

Andrew McIvor, Alan Kaplan in npj Primary Care Respiratory Medicine (2020)

Article

Switching Inhalers: A Practical Approach to Keep on UR RADAR

The choice of an inhaler device is often as important as the medication put in it to achieve optimal outcomes for our patients with asthma and/or COPD. With a multitude of drug–device combinations available, o...

Alan Kaplan, Job F. M. van Boven in Pulmonary Therapy (2020)

Article

Comparing LAMA with LABA and LTRA as add-on therapies in primary care asthma management

The Global Initiative for Asthma recommends a stepwise approach to adjust asthma treatment to the needs of individual patients; inhaled corticosteroids (ICS) remain the core pharmacological treatment. However,...

Alan Kaplan, J. Mark FitzGerald, Roland Buhl… in npj Primary Care Respiratory Medicine (2020)

Article

Impact of comorbid conditions on asthmatic adults and children

Comorbid conditions (comorbidities) can complicate the diagnosis and management of asthma. In different age groups, comorbid conditions can present varying challenges, including diagnostic confusion due to mim...

Alan Kaplan, Stanley J. Szefler… in npj Primary Care Respiratory Medicine (2020)

Article

A comparison of tiotropium, long-acting β₂-agonists and leukotriene receptor antagonists on lung function and exacerbations in paediatric patients with asthma

Diagnosing and treating asthma in paediatric patients remains challenging, with many children and adolescents remaining uncontrolled despite treatment. Selecting the most appropriate pharmacological treatment ...

Christian Vogelberg, Stanley Goldstein, LeRoy Graham, Alan Kaplan… in Respiratory Research (2020)

Article

A multi-stakeholder perspective on asthma care in Canada: findings from a mixed methods needs assessment in the treatment and management of asthma in adults

Although several aspects of asthma care have been identified as being sub-optimal in Canada, such as patient education, practice guideline adoption, and access to care, there remains a need to determine the ex...

Suzanne Murray, Sara Labbé, Alan Kaplan… in Allergy, Asthma & Clinical Immunology (2018)

Article

Solving the mystery of the yellow zone of the asthma action plan

Samir Gupta, Alan Kaplan in npj Primary Care Respiratory Medicine (2018)

Article

Cohort Analysis of Exacerbation Rates in Adolescent and Adult Patients Initiating Inhaled Corticosteroids for Asthma: Different Dose–Response Profile by Particle Size

Targeting small airway inflammation could lead to improved clinical outcomes in asthma. Previous observational studies concluded that therapy with extrafine-particle [mass median aerodynamic diameter (MMAD) <...

Dirkje S. Postma, Alan Kaplan, Joan B. Soriano, Jonathon Grigg… in Pulmonary Therapy (2017)

Article

A systematic review of comparative studies of tiotropium Respimat® and tiotropium HandiHaler® in patients with chronic obstructive pulmonary disease: does inhaler choice matter?

In many countries worldwide, the long-acting anticholinergic drug tiotropium is available as a dry powder formulation delivered by means of the HandiHaler® inhalation device and as an aqueous solution delivere...

Ronald Dahl, Alan Kaplan in BMC Pulmonary Medicine (2016)

Article

Quality of asthma care under different primary care models in Canada: a population-based study

Previous research has shown variations in quality of care and patient outcomes under different primary care models. The objective of this study was to use previously validated, evidence-based performance indic...

Teresa To, Jun Guan, **gqin Zhu, M Diane Lougheed, Alan Kaplan… in BMC Family Practice (2015)

Article

Is there a rationale and role for long-acting anticholinergic bronchodilators in asthma?

Despite current guidelines and the range of available treatments, over a half of patients with asthma continue to suffer from poor symptomatic control and remain at risk of future worsening. Although a number ...

David Price, Leonard Fromer, Alan Kaplan… in npj Primary Care Respiratory Medicine (2014)

Article

Chronic obstructive pulmonary disease and exacerbations: Patient insights from the global Hidden Depths of COPD survey

Although chronic obstructive pulmonary disease (COPD) is a major global health burden there is a lack of patient awareness of disease severity, particularly in relation to exacerbations.

Neil Barnes, Peter MA Calverley, Alan Kaplan, Klaus F Rabe in BMC Pulmonary Medicine (2013)

Article

Canadian clinical practice guidelines for acute and chronic rhinosinusitis

This document provides healthcare practitioners with information regarding the management of acute rhinosinusitis (ARS) and chronic rhinosinusitis (CRS) to enable them to better meet the needs of this patient ...

Martin Desrosiers, Gerald A Evans, Paul K Keith… in Allergy, Asthma & Clinical Immunology (2011)

Article

Can asthma control be improved by understanding the patient's perspective?

Clinical trials show that asthma can be controlled in the majority of patients, but poorly controlled asthma still imposes a considerable burden. The level of asthma control achieved reflects the behaviour of ...

Rob Horne, David Price, Jen Cleland, Rui Costa, Donna Covey… in BMC Pulmonary Medicine (2007)