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Article
Open AccessIsolated massive pleural effusion as a manifestation of chronic graft versus host disease successfully treated with corticosteroid
Isolated pleural effusion is a rare manifestation of chronic graft versus host disease (cGVHD) after hematopoietic stem cell transplantation (HSCT). We herein report a 58-year-old woman presenting with massive...
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Article
Usefulness of the preoperative thoracic inlet angle in comparison to the T1 slope for predicting cervical kyphosis after laminoplasty
Thoracic inlet angle (TIA) is a sagittal radiographic parameter with a constant value regardless of posture and is significantly correlated with the sagittal balance of the cervical spine. However, the practic...
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Article
Recurrent DDX41 mutation in very late relapse after allogeneic stem cell transplantation
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Article
Open AccessInduction of CYP3A activity by dexamethasone may not be strong, even at high doses: insights from a case of tacrolimus co-administration
Dexamethasone (DEX) induces CYP3A activity in a concentration-dependent manner. However, no study has examined changes in the blood concentration of CYP3A substrate drugs when DEX is administered at high doses...
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Article
Open AccessRisk factors for early mortality in elderly patients with unstable isolated C2 odontoid fracture treated with halo-vest or surgery
The aim of this study was to compare in-hospital mortality of three procedures –halo-vest immobilization, anterior spinal fixation (ASF), and posterior spinal fixation (PSF)– in the treatment of elderly patien...
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Article
Open AccessRecurrent bilateral adrenal infarction with myelodysplastic/myeloproliferative neoplasm-unclassifiable (MDS/MPN-U): a case report
Bilateral adrenal infarction is rare and only a small number of cases have been reported so far. Adrenal infarction is usually caused by thrombophilia or a hypercoagulable state, such as antiphospholipid antib...
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Article
Open AccessExpansion of large granular lymphocytes after autologous hematopoietic stem cell transplantation
Expansion of large granular lymphocytes (LGLs) is sometimes observed in allogeneic hematopoietic stem cell transplantation (HSCT) recipients, and is reported to be associated with a favorable transplant outcom...
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Article
Development of Epstein–Barr virus-associated lymphoproliferative disorder and hemophagocytic lymphohistiocytosis during long-term lenalidomide maintenance therapy in multiple myeloma
Reactivation of Epstein–Barr virus (EBV) has been considered a very rare event among patients on immunomodulatory drugs (IMiDs) such as lenalidomide, and an association between the two has not well been recogn...
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Article
Daratumumab plus lenalidomide and dexamethasone for relapsed POEMS syndrome with bone plasmacytoma harboring 17p deletion
The standard therapies for polyneuropathy, organomegaly, endocrinopathy, monoclonal protein, and skin changes (POEMS) syndrome are radiation therapy, high-dose chemotherapy followed by autologous stem cell tra...
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Article
Clinical characteristics of steroid-responsive but dependent chronic graft-versus-host disease: a multicenter retrospective analysis
Chronic graft-versus-host disease (cGVHD) is a long-term complication of allogeneic hematopoietic stem cell transplantation. The clinical importance of long-term corticosteroid dependency in steroid-responsive...
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Article
Obinutuzumab and reduced bendamustine is effective for elderly patients with follicular lymphoma
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Article
Impact of the preoperative nutritional status on postoperative kyphosis in geriatric patients undergoing cervical laminoplasty
This study aimed to determine the association of preoperative malnutrition with an increased risk of cervical kyphosis after laminoplasty in geriatric patients with cervical spondylotic myelopathy (CSM).
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Article
Severe infections and renal dysfunction during immunosuppressive therapy with cyclosporine A for aplastic anemia
Although immunosuppressive therapy (IST) with cyclosporine A (CyA) has been widely used in patients with aplastic anemia (AA), little attention has been given to its safety. This study aimed to clarify the adv...
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Article
R-GCD regimen in elderly patients with relapsed or refractory aggressive non-Hodgkin’s B-cell lymphoma: a retrospective single-center analysis
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Article
Open AccessTaurine supplementation enhances endurance capacity by delaying blood glucose decline during prolonged exercise in rats
Taurine enhances physical performance; however, the underlying mechanism remains unclear. This study examined the effect of taurine on the overtime dynamics of blood glucose concentration (BGC) during enduranc...
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Blood Taurine Dynamics in Captive Lions: Relationship with Feed and Bile Acid Composition
Taurine is an essential nutrient for felines including lions. Various severe symptoms induced by taurine deficiency have been reported for domestic and captive felines. Particularly for captive lions in zoos, ...
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Chapter
Impaired Bile Acid Synthesis in a Taurine-Deficient Cat Model
Deficiency of the functional amino acid-like compound taurine induced in cats by taurine-depleted food was previously shown to significantly decrease the levels of taurine-conjugated bile acids (BAs) and signi...
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Article
A case of thymoma showing significant tumor reduction after anti-thymocyte globulin
A 71-year-old female with type B3 thymoma developed severe aplastic anemia. Anti-thymocyte globulin was administered with glucocorticoids and cyclosporin A as the treatment for aplastic anemia. Computed tomogr...
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Article
Environmental factors, medical and family history, and comorbidities associated with primary biliary cholangitis in Japan: a multicenter case–control study
Primary biliary cholangitis (PBC) is considered to be caused by the interaction between genetic background and environmental triggers. Previous case–control studies have indicated the associations of environme...
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Article
Clinical features and early post-operative complications of isolated C2 odontoid fractures: a retrospective analysis using a national inpatient database in Japan
To examine the clinical features and post-treatment complications in patients with isolated C2 odontoid fractures.
