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Open AccessRace and ethnicity in the COVID-19 Critical Care Consortium: demographics, treatments, and outcomes, an international observational registry study
Improving access to healthcare for ethnic minorities is a public health priority in many countries, yet little is known about how to incorporate information on race, ethnicity, and related social determinants ...
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Open AccessCost-effectiveness of left atrial appendage closure for stroke prevention in atrial fibrillation: a systematic review appraising the methodological quality
The increasing global prevalence of atrial fibrillation (AF) has led to a growing demand for stroke prevention strategies, resulting in higher healthcare costs. High-quality economic evaluations of stroke prev...
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Open AccessA discrete choice experiment to elicit preferences for a liver screening programme in Queensland, Australia: a mixed methods study to select attributes and levels
In Australia, the overall prevalence of liver disease is increasing. Maximising uptake of community screening programmes by understanding patient preferences is integral to develo** consumer-centred care mod...
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Open AccessEvidence of questionable research practices in clinical prediction models
Clinical prediction models are widely used in health and medical research. The area under the receiver operating characteristic curve (AUC) is a frequently used estimate to describe the discriminatory ability ...
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Open AccessReducing waste in collection of quality-of-life data through better reporting: a case study
This study describes the reporting of the preference-based health-related quality-of-life (HRQOL) instrument, the EQ-5D, and proposes strategies to improve reporting and reduce research waste. The EQ-5D is a v...
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Open AccessTranslation of the geriatric emergency department intervention into other emergency departments: a post implementation evaluation of outcomes for older adults
Increasing numbers of older adults with complex health deficits presenting to emergency departments has prompted the development of innovative models of care. One such model designed to reduce poor outcomes as...
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Open AccessIs There Broad-Based Support in High-Income Countries for COVID-19 Vaccine Donation? Evidence from Seven Countries
Many high-income countries (HICs) have now vaccinated a substantial proportion of their population against COVID-19. Many low-income countries (LICs) may need to wait until at least 2022 before even the most v...
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Open AccessDevelopment and validation of a risk index to predict kidney graft survival: the kidney transplant risk index
Kidney graft failure risk prediction models assist evidence-based medical decision-making in clinical practice. Our objective was to develop and validate statistical and machine learning predictive models to p...
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Open AccessTime-to-event analysis in economic evaluations: a comparison of modelling methods to assess the cost-effectiveness of transplanting a marginal quality kidney
Economic-evaluations using decision analytic models such as Markov-models (MM), and discrete-event-simulations (DES) are high value adds in allocating resources. The choice of modelling method is critical beca...
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Open AccessHow Should a Safe and Effective COVID-19 Vaccine be Allocated? Health Economists Need to be Ready to Take the Baton
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Open AccessAn implementation science approach for develo** and implementing a dietitian-led model of care for gestational diabetes: a pre-post study
There is strong evidence that women with gestational diabetes mellitus (GDM) who receive a minimum of three appointments with a dietitian may require medication less often. The aim of this study was to evaluat...
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Open AccessDeceased donor kidney allocation: an economic evaluation of contemporary longevity matching practices
Matching survival of a donor kidney with that of the recipient (longevity matching), is used in some kidney allocation systems to maximize graft-life years. It is not part of the allocation algorithm for Austr...
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Open AccessGroup Testing for SARS-CoV-2: Forward to the Past?
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Open AccessProtocol for a randomised trial testing a community fibrosis assessment service for patients with suspected non-alcoholic fatty liver disease: LOCal assessment and triage evaluation of non-alcoholic fatty liver disease (LOCATE-NAFLD)
Non-alcoholic fatty liver disease (NAFLD) is the most common type of chronic liver disease in Australia and its recent increase mirrors the obesity and type 2 diabetes epidemics. Currently, many patients who p...
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Open AccessRegistered Reports: Time to Radically Rethink Peer Review in Health Economics
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Open AccessThe Geriatric Emergency Department Intervention model of care: a pragmatic trial
To evaluate a Geriatric Emergency Department Intervention (GEDI) model of service delivery for adults aged 70 years and older.
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Open AccessThe effects of normovolemic anemia and blood transfusion on cerebral microcirculation after severe head injury
Cerebral regional microcirculation is altered following severe head injury. In addition to tissue disruption, partial pressure of tissue oxygenation is impaired due to an increase in the oxygen tissue gradient...
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Open AccessA research pathway for the study of the delivery and disposition of nebulised antibiotics: an incremental approach from in vitro to large animal models
Nebulised antibiotics are frequently used for the prevention or treatment of ventilator-associated pneumonia. Many factors may influence pulmonary drug concentrations with inaccurate dosing schedules potential...
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Open AccessA structure, process and outcome evaluation of the Geriatric Emergency Department Intervention model of care: a study protocol
Emergency departments are chaotic environments in which complex, frail older persons living in the community and residential aged care facilities are sometimes subjected to prolonged emergency department lengt...
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Predictors of health-related quality of life in people with a complex chronic disease including multimorbidity: a longitudinal cohort study
Factors that predict the health-related quality of life (HRQoL) of people with complex chronic diseases have not been investigated to date. Determining the impact of disease on daily activities is a factor tha...