-
Article
Maternal Lifestyles Study (MLS): Prenatal Cocaine/Opiate (C/O) Exposure Is Unrelated to Changes in Bayley II Performance between One and Two Years. (NICHD Neonatal Research Network, NIDA, ACYF, CSAT; Bethesda, MD)
-
Article
Elicited Data and Incorporation of Expert Opinion for Statistical Inference in Spatial Studies
Spatial data are often sparse by nature. However, in many instances, information may exist in the form of “soft” data, such as expert opinion. Scientists in the field often have a good understanding of the phe...
-
Article
Open AccessBreastfeeding practices in a cohort of inner-city women: the role of contraindications
Little is known about the role of breastfeeding contraindications in breastfeeding practices. Our objectives were to 1) identify predictors of breastfeeding initiation and duration among a cohort of predominat...
-
Chapter and Conference Paper
Stochastic Spectral Density Analysis on Network Traffic Characterization
In the network traffic, the nature of the input output data/signal signals are used to demonstrate the statistical characterization of the traffic performance. Observations of traffic on network links typicall...
-
Article
The Effect of Parenting Stress on Child Behavior Problems in High-Risk Children with Prenatal Drug Exposure
Objective To examine the relationship between early parenting stress and later child behavior in a high-risk sample and measure the effect of drug exposure on the relationship between parenting stress and child b...
-
Article
Circulating β Chemokine and MMP 9 as Markers of Oxidative Injury in Extremely Low Birth Weight Infants
Matrix metalloproteinases (MMPs) and chemokines seem to be induced by hyperoxia in preclinical studies. We hypothesized that O2 exposure immediately after birth is associated with altered blood spot MMP 9 and β c...
-
Article
Open AccessComplementary feeding: a Global Network cluster randomized controlled trial
Inadequate and inappropriate complementary feeding are major factors contributing to excess morbidity and mortality in young children in low resource settings. Animal source foods in particular are cited as es...
-
Article
Early Nutrition Mediates the Influence of Severity of Illness on Extremely LBW Infants
To evaluate whether differences in early nutritional support provided to extremely premature infants mediate the effect of critical illness on later outcomes, we examined whether nutritional support provided t...
-
Article
Cytokine profiles of preterm neonates with fungal and bacterial sepsis
Information on cytokine profiles in fungal sepsis (FS), an important cause of mortality in extremely low birthweight (ELBW) infants, is lacking. We hypothesized that cytokine profiles in the first 21 d of life...
-
Article
Effect of inborn vs. outborn delivery on neurodevelopmental outcomes in infants with hypoxic–ischemic encephalopathy: secondary analyses of the NICHD whole-body cooling trial
The effect of birth location on hypothermia-related outcomes has not been rigorously examined in the literature. In this study, we determined whether birth location had an impact on the benefits of whole-body ...
-
Article
Outcome of Extremely Preterm Infants (<1,000 g) With Congenital Heart Defects From the National Institute of Child Health and Human Development Neonatal Research Network
Little is known about the outcomes of extremely low birth weight (ELBW) preterm infants with congenital heart defects (CHDs). The aim of this study was to assess the mortality, morbidity, and early childhood o...
-
Article
Association Between Blood Spot Transforming Growth Factor-β and Patent Ductus Arteriosus in Extremely Low-Birth Weight Infants
Permanent ductal closure involves anatomic remodeling, in which transforming growth factor (TGF)-β appears to play a role. Our objective was to evaluate the relationship, if any, between blood spot TGF-β on da...
-
Article
Pharmacokinetics and safety of a single intravenous dose of myo-inositol in preterm infants of 23–29 wk
Myo-inositol given to preterm infants with respiratory distress has reduced death, increased survival without bronchopulmonary dysplasia, and reduced severe retinopathy of prematurity in two randomized trials. Ph...
-
Reference Work Entry In depth
Longitudinal Data Analysis
-
Reference Work Entry In depth
Logistic Regression
-
Article
Apolipoprotein E genotype and outcome in infants with hypoxic–ischemic encephalopathy
Adults with the apolipoprotein E (APOE) gene alleles e4 and e2 are at high risk of poor neurological outcome after brain injury. The e4 allele has been associated with cerebral palsy (CP), and the e2 allele ha...
-
Article
Open AccessPreconception maternal nutrition: a multi-site randomized controlled trial
Research directed to optimizing maternal nutrition commencing prior to conception remains very limited, despite suggestive evidence of its importance in addition to ensuring an optimal nutrition environment in...
-
Article
Cytokines associated with necrotizing enterocolitis in extremely-low-birth-weight infants
The goal was to identify cytokines associated with necrotizing enterocolitis (NEC). Based on our earlier reports of decreased tissue expression of transforming growth factor (TGF)-β, we hypothesized that infan...
-
Article
Open AccessInhaled PGE1 in neonates with hypoxemic respiratory failure: two pilot feasibility randomized clinical trials
Inhaled nitric oxide (INO), a selective pulmonary vasodilator, has revolutionized the treatment of neonatal hypoxemic respiratory failure (NHRF). However, there is lack of sustained improvement in 30 to 46% of...
-
Article
Open AccessStop** guidelines for an effectiveness trial: what should the protocol specify?
Despite long-standing problems in decisions to stop clinical trials, stop** guidelines are often vague or unspecified in the trial protocol. Clear, well-conceived guidelines are especially important to assis...
