Abstract
An approach to the simultaneous registration of ginsenosides in herbal extracts and commercial products was developed on the basis of liquid chromatography/mass spectrometry. The approach was validated for four major ginsenosides: Rg1, Rb1, Rf, and Re determined in extracts from roots of Panax ginseng, a phyto-formulation and a tea produced from the roots. The limits of detection for two applied detection modes belong to the range 0.001–0.01 μg/mL. Samples were analyzed by reversed-phase chromatography with a C18 adsorbent. Electrospray ionization in the positive ion mode and a hybrid linear-trap tandem mass spectrometry detection system were used to monitor compounds.
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Original Russian Text © I.A. Rodin, A.N. Stavrianidi, A.V. Braun, O.A. Shpigun, E.I. Berizovskaya, 2013, published in Mass-spektrometria, 2013, Vol. 10, No. 2, pp. 129–135.
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Rodin, I.A., Stavrianidi, A.N., Braun, A.V. et al. Simultaneous determination of ginsenosides by high-performance liquid chromatography with tandem mass spectrometry detection. J Anal Chem 69, 1252–1258 (2014). https://doi.org/10.1134/S1061934814130097
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DOI: https://doi.org/10.1134/S1061934814130097