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  1. No Access

    Article

    Differential effect of insulin-like growth factor-I and growth hormone on hypothalamic regulation of growth hormone secretion in the rat

    Pharmacological administration of either growth hormone (GH) or insulin-like growth factor I (IGF-I) were reported to inhibit endogenous GH release in humans and in the laboratory animal. We have evaluated the...

    I. Gil Ad Ph.D., A. Weizman, A. Silbergeld… in Journal of Endocrinological Investigation (1996)

  2. No Access

    Article

    Growth hormone therapy in normal short children induces a transitory decrease in plasma growth hormone releasing hormone levels and in human growth hormone responsiveness to exogenous growth hormone releasing hormone

    A three-month study of the effect of growth hormone (hGH) therapy (0.1 U/kg/day sc) on plasma levels of GH releasing hormone (GHRH), somatostatin and insulin-like growth factor I (IGF-I) and on the hGH respons...

    I. Gil-Ad, B. Klinger, A. Pertzelan, B. Erster… in Journal of Endocrinological Investigation (1992)

  3. Article

    42 SERUM GROWTH HORMONE BINDING PROTEIN (GH-BP) IN PRE-PUBERTAL CHILDREN IS CORRELATED WITH HEIGHT

    Recently serum GH-BP has been shown to have identical N-terminal amino acid sequence as the tissue hGH receptor. Serum hGH levels and the specific binding activity of GH-BP (expressed as % of GH-BP activity of...

    A Silbergeld, L Lazar, R Eshet, Z Dux, B Klinger, B Erster, R Keret… in Pediatric Research (1988)

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  4. Article

    108 IGF-BINDING TO READ BLOOD CELLS OF SIIORT AND TALL BOYS. COMPARIOSON WITH CH-BINDING PROTEIN LEVELS

    Binding of 125I-ICF-I to red blood cells (RBC) was determined in 12 prepubertal boys aged 7-9 yrs, 6 with short stature ( ≤ 2 SD height) and 6 with tall stature ( ≥ 2 SD height). Concomitantly blood hCH, IGF-I an...

    R Eshet, Z Dux, B Klinger, A Silbergeld, Z Laron in Pediatric Research (1988)

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  5. Article

    76 PROLACTIN SECRETION IN 149 hGH DEFICIENT CHILDREN

    One hundred forty nine children and adolescents with growth hormone (hGH) deficiency were reviewed retrospectively in relation to plasma basal and TRH stimulated prolactin (Prl) levels before and during long-t...

    L Witz, A Silbergeld, Z Laron in Pediatric Research (1988)

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  6. Article

    COMPARISON OF TWO RTA METHODS FOR IGF-1 USING EXTRACTED SERA OR WHOLE PLASMA

    Parallel measurements of IGF-1 (SMC) levels were made in extracted sera by the INCSTAR RIA, and in plasma by the NICHOLS RIA. Four clinical groups were examined: GR 1 - untreated hGH def.; GR 2 - short stature...

    A Silbergeld, L Jaber, Z Laron in Pediatric Research (1988)

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  7. Article

    24-HOUR GH SECRETION PATTERN IN FAMILIAL TALL STATURE

    GH secretion was measured by 30 mins. sampling over 24 hrs (using a Cormed pump) in 3 tall girls (aged 12, 14 & 16 yrs), belonging to a family of tall stature (4 of 7 sibs & parents were above 90th centile). I...

    Z Dickerman, M Kalijman, R Keret, A Silbergeld, B Bauman, A Zacharia… in Pediatric Research (1986)

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  8. Article

    Stimulation of 3H glucosamine incorporation Into chick cartilage as an Index of serum somatomedin activity

    Pelvic cartilages from chick embryos were incubated with precursors of proteoglycan synthesis: 3H glucosamine, 3H serine and 35S, in the presence of sera from patients with isolated growth hormone deficiency (...

    A Silbergeld, R Mamet, A Tacoli, Z Nevo, Z Laron in Pediatric Research (1981)

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