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Article
Enterococcus Phage vB_EfaS_HEf13 as an Anti-Biofilm Agent Against Enterococcus faecalis
Enterococcus faecalis is a Gram-positive bacterium that is frequently found in the periapical lesion of patients with apical periodontitis. Its biofilm formation in root canal is closely related to the developmen...
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Article
Open AccessOutbreak investigation of Serratia marcescens bloodstream infection in an obstetric ward for high-risk pregnant women
Serratia marcescens is a gram-negative bacterium that is widespread in the environment. S. marcescens bacteremia can be fatal during pregnancy and cause persistent chorioamnionitis. This study reports an outbreak...
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Article
Correction to: Protracted course of SARS‑CoV‑2 pneumonia in moderately to severely immunocompromised patients
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Article
Protracted course of SARS-CoV-2 pneumonia in moderately to severely immunocompromised patients
There have been few studies comparing the clinical characteristics and outcomes of SARS-CoV-2 pneumonia in individuals with and without moderately to severely immunocompromised conditions. We reviewed adult pa...
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Article
A virtual memory CD8+ T cell-originated subset causes alopecia areata through innate-like cytotoxicity
Virtual memory T (TVM) cells are a T cell subtype with a memory phenotype but no prior exposure to foreign antigen. Although TVM cells have antiviral and antibacterial functions, whether these cells can be pathog...
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Article
Short-chain fatty acids inhibit the biofilm formation of Streptococcus gordonii through negative regulation of competence-stimulating peptide signaling pathway
Streptococcus gordonii, a Gram-positive commensal bacterium, is an opportunistic pathogen closely related to initiation and progression of various oral diseases, such as periodontitis and dental caries. Its biofi...
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Article
Open AccessPrinciple of restoration ecology reflected in the process creating the National Institute of Ecology
The creation of the National Institute of Ecology began as a national alternative project to preserve mudflats instead of constructing the industrial complexes by reclamation, and achieve regional development....
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Article
Absolute quantification of tumor-infiltrating immune cells in high-grade glioma identifies prognostic and radiomics values
To understand the tumor immune microenvironment precisely, it is important to secure the quantified data of tumor-infiltrating immune cells, since the immune cells are true working unit. We analyzed unit immun...
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Article
Lactobacillus plantarum lipoteichoic acid disrupts mature Enterococcus faecalis biofilm
Apical periodontitis is caused by biofilm-mediated root canal infection. Early phase oral bacterial biofilms are inhibited by Lactobacillus plantarum lipoteichoic acid (Lp.LTA). However, mature biofilms that deve...
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Article
Abnormal shoot growth in Korean red pine as a response to microclimate changes due to urbanization in Korea
Impacts of climate change (e.g., abnormal growth in plants, early flowering, and shifting vegetation zones) are being detected throughout the world. Urban land use and its resulting microclimates work in conju...
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Article
Open AccessDietary fat intake and age modulate the composition of the gut microbiota and colonic inflammation in C57BL/6J mice
More than half of the adult population worldwide is overweight or obese, while excess adiposity has been linked to chronic low-grade inflammation, contributing to the development of chronic diseases. Recent st...
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Article
Open AccessSpatial distribution of vegetation along the environmental gradient on the coastal cliff and plateau of Janggi peninsula (Homigot), southeastern Korea
Cliffs are a major plant habitat around the coastal area, but in contrast to sand dunes and salt marshes, they have been little investigated in Korea. There are simple descriptions of cliff vegetation in studi...
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Article
Lipoteichoic acids of lactobacilli inhibit Enterococcus faecalis biofilm formation and disrupt the preformed biofilm
Enterococcus faecalis, a Gram-positive bacterium commonly isolated in patients with refractory apical periodontitis, invades dentin tubules easily and forms biofilms. Bacteria in biofilms, which contribute to rec...
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Article
Open AccessAsxl1 exerts an antiproliferative effect on mouse lung maturation via epigenetic repression of the E2f1-Nmyc axis
Although additional sex combs-like 1 (ASXL1) has been extensively described in hematologic malignancies, little is known about the molecular role of ASXL1 in organ development. Here, we show that Asxl1 ablation i...
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Article
Gamma-irradiation of Streptococcus pneumoniae for the use as an immunogenic whole cell vaccine
Streptococcus pneumoniae is a major respiratory pathogen that causes millions of deaths worldwide. Although subunit vaccines formulated with the capsular polysaccharides or their protein conjugates are currently-...
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Article
Dissociation of Systemic Glucose Homeostasis from Triacylglyceride Accumulation by Reduced Acsl6 Expression in Skeletal Muscle
Long chain acyl-CoA synthetase (ACSL) is an enzyme that activates fatty acids before they are further metabolized. ACSL6 is the one of main ACSL isoforms exclusively expressed in skeletal muscle, but the conse...
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Article
Open AccessEdge effects confirmed at the clear-cut area of Korean red pine forest in Ul**, eastern Korea
Forest edges create distinctive ecological space as adjacent constituents, which distinguish between different ecosystems or land use types. These edges are made by anthropogenic or natural disturbance and aff...
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Article
The synthetic human beta-defensin-3 C15 peptide exhibits antimicrobial activity against Streptococcus mutans, both alone and in combination with dental disinfectants
Streptococcus mutans is a major etiologic agent of human dental caries that forms biofilms on hard tissues in the human oral cavity, such as tooth and dentinal surfaces. Human β-d...
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Article
Open AccessThe combination of Artemisia princeps Pamp, Leonurus japonicas Houtt, and Gardenia jasminoides Ellis fruit attenuates the exacerbation of energy, lipid, and glucose by increasing hepatic PGC-1α expression in estrogen-deficient rats
Artemisia princeps Pamp (APP), Leonurus japonicas Houtt (LJH), and Gardenia jasminoides Ellis fruit (GJE) have been traditionally used in East Asia to treat women’s diseases related to...
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Article
Synthesis of YAG:Ce3+ phosphor powders employing several types of alumina seeds
YAG:Ce3+ phosphor powders were synthesized using Al2O3 seeds to control the powder morphology and size through solution chemical processing. A PVA solution was added to slurry-type precursors for homogeneous mixi...
