319 Result(s)
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**zheng Wang
Life Sciences
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Article
Correction: Study on vibration performance and comfort of glulam beam and deck floor
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Study on vibration performance and comfort of glulam beam and deck floor
This paper presents the dynamic characteristics of the glued-laminated-timber (glulam) floor within China's tallest timber office building and establishes a Finite Element (FE) model. The veracity of the FE mo...
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Article
Open AccessDistraction force promotes the osteogenic differentiation of Gli1+ cells in facial sutures via primary cilia-mediated Hedgehog signaling pathway
Trans-sutural distraction osteogenesis (TSDO) involves the application of distraction force to facial sutures to stimulate osteogenesis. Gli1+ cells in the cranial sutures play an important role in bone growth. H...
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Open AccessMutations in wheat TaAPA2 gene result in pleiotropic effects on plant architecture
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A neural m6A pathway regulates behavioral aggregation in migratory locusts
RNA N6-methyladenosine (m6A), as the most abundant modification of messenger RNA, can modulate insect behaviors, but its specific roles in aggregation behaviors remain unexplored. Here, we conducted a comprehensi...
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Glycolytic enzyme PFKL governs lipolysis by promoting lipid droplet–mitochondria tethering to enhance β-oxidation and tumor cell proliferation
Lipid droplet tethering with mitochondria for fatty acid oxidation is critical for tumor cells to counteract energy stress. However, the underlying mechanism remains unclear. Here, we demonstrate that glucose ...
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Open AccessEpitope map** and establishment of a blocking ELISA for mAb targeting the p72 protein of African swine fever virus
The African swine fever virus (ASFV) has the ability to infect pigs and cause a highly contagious acute fever that can result in a mortality rate as high as 100%. Due to the viral epidemic, the pig industry wo...
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Transcriptome Analysis Reveals the Role of Sucrose and Starch Metabolism and Systemic Homeostasis in Seed Abortion in Distant Hybrids of Peony
Peony is a flower species with great ornamental value. Germplasm innovation is urgently needed due to the rapid development of peony industrialization around the world. However, the occurrence of seed abortion...
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Open AccessAndrogen deprivation induces neuroendocrine phenotypes in prostate cancer cells through CREB1/EZH2-mediated downregulation of REST
Although effective initially, prolonged androgen deprivation therapy (ADT) promotes neuroendocrine differentiation (NED) and prostate cancer (PCa) progression. It is incompletely understood how ADT transcripti...
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Article
Clpf encodes pentatricopeptide repeat protein (PPR5) and regulates pink flesh color in watermelon (Citrullus lanatus L.)
The gene controlling pink flesh in watermelon was finely mapped to a 55.26-kb region on chromosome 6. The prime candidate gene, Cla97C06G122120 (ClPPR5), was identified through forward genetics.
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Theoretical carrying capacity of grasslands and early warning for maintaining forage-livestock balance in the Qilian Mountains, northwest China
An in-depth understanding of the relationship between the theoretical carrying capacity of grasslands and the forage-livestock balance is crucial for maintaining ecological equilibrium in grasslands and guidin...
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Open AccessHuanglian-Hongqu herb pair improves nonalcoholic fatty liver disease via NF-κB/NLRP3 pathway in mice: network pharmacology, molecular docking and experimental validation
The Huanglian-Hongqu herb pair (HH) is a carefully crafted traditional Chinese herbal compound designed to address disorders related to glucose and lipid metabolism. Its primary application lies in treating hy...
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Effect of dietary Bifidobacterium animalis subsp. lactis BLa80 on growth, immune response, antioxidant capacity, and intestinal microbiota of juvenile Japanese seabass (Lateolabrax japonicus)
To evaluate the potential of Bifidobacterium animalis subsp. lactis BLa80 (BLa80) as a probiotic for Japanese seabass (Lateolabrax japonicus) aquaculture, we assessed the effects of BLa80 on the growth, immune re...
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Revealing the role of CCoAOMT1: fine-tuning bHLH transcription factors for optimal anther development
The tapetum, a crucial innermost layer encompassing male reproductive cells within the anther wall, plays a pivotal role in normal pollen development. The transcription factors (TFs) bHLH010/089/091 redundantl...
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Establishment and characterization of DPC-X4: a novel mixed-type ampullary cancer cell line
Mixed-type ampullary cancer is a distinct subtype of ampullary cancer that manifests a merging of the biological characteristics of both intestinal and pancreaticobiliary subtypes. The absence of established c...
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Open AccessHRD1-induced TMEM2 ubiquitination promotes ER stress-mediated apoptosis through a non-canonical pathway in intestinal ischemia/reperfusion
Intestinal ischemia/reperfusion (I/R) injury is a typical pathological course in the clinic with a high morbidity rate. Recent research has pointed out the critical role of ubiquitination during the occurrence...
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Open AccessCIP2A induces PKM2 tetramer formation and oxidative phosphorylation in non-small cell lung cancer
Tumor cells are usually considered defective in mitochondrial respiration, but human non-small cell lung cancer (NSCLC) tumor tissues are shown to have enhanced glucose oxidation relative to adjacent benign lu...
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Open AccessCoordination among flower pigments, scents and pollinators in ornamental plants
Flower color and scent, crucial qualitative characteristics of ornamental plants, display extensive variation. These distinct pigments and scents play a key role in attracting specific pollinators. While previ...
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Data mining-based identification of epigenetic signatures with discrimination potential of lung adenocarcinoma and squamous cell carcinoma
Mounting evidence suggests that lung adenocarcinoma (LAC) and lung squamous cell carcinoma (LSC) have different biological behaviors and therapeutic regimens in clinical practice. However, limited improvements...
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Variant of the lactase LCT gene explains association between milk intake and incident type 2 diabetes
Cow’s milk is frequently included in the human diet, but the relationship between milk intake and type 2 diabetes (T2D) remains controversial. Here, using data from the Hispanic Community Health Study/Study of...
