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17,264 Result(s)
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Article
Distribution Law of Occurrence State and Content Prediction of Deep CBM: A Case Study in the Ordos Basin, China
The deep coalbed methane (CBM) resources in the Ordos Basin are enormous, and their exploration and development breakthrough are among the critical ways to improve CBM production in China. The occurrence state...
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Rationale and Design of the IMPROVE Trial: A Multicenter, Randomized, Controlled, Open-label, Blinded-endpoint Trial Assessing the Efficacy of Remote Ischemic Conditioning in Patients Undergoing Off-Pump Coronary Artery Bypass Grafting
Despite the appearance of off-pump coronary artery bypass grafting (CABG), ischemia–reperfusion injury (IRI) in the perioperative period still arouses concerns of clinicians. Remote ischemic conditioning (RIC)...
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Far-Infrared Therapy Based on Graphene Ameliorates High-Fat Diet-Induced Anxiety-Like Behavior in Obese Mice via Alleviating Intestinal Barrier Damage and Neuroinflammation
The consumption of a high-fat diet (HFD) has been implicated in the etiology of obesity and various neuropsychiatric disturbances, including anxiety and depression. Compelling evidence suggests that far-infrar...
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Fabrication of flexible nitrogen-doped graphene micro-supercapacitors by laser-induced self-made precursors
With the wide application of portable wearable devices, a variety of electronic energy storage devices, including micro-supercapacitors (MSCs), have attracted wide attention. Laser-induced graphene (LIG) is wi...
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Acetylcytidine modification of Amotl1 by N-acetyltransferase 10 contributes to cardiac fibrotic expansion in mice after myocardial infarction
Cardiac fibrosis is a pathological scarring process that impairs cardiac function. N-acetyltransferase 10 (Nat10) is recently identified as the key enzyme for the N4-acetylcytidine (ac4C) modification of mRNAs...
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Pharmacological inhibition of Kir4.1 evokes rapid-onset antidepressant responses
Major depressive disorder, a prevalent and severe psychiatric condition, necessitates development of new and fast-acting antidepressants. Genetic suppression of astrocytic inwardly rectifying potassium channel...
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Loss-of-function mutation in DDX53 associated with hereditary spastic paraplegia-like disorder
DEAD-box helicase 53 (DDX53) is a member of the DEAD-box protein family of RNA helicases. Unlike other family members that are responsible for RNA metabolism, the biological function of DDX53 and its impact on...
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Article
Optical and electrical anisotropy regulation engineering of low-dimensional materials toward polarized detection and imaging applications
Polarized-sensitive image sensors are a kind of photodetector with great development potential due to their enhanced ability to detect and identify the target objects from the aspect of spatial, spectral and p...
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Article
Power-Line Extraction and Modelling from 3D Point Clouds Data Based on K-D Tree DBSCAN Algorithm
In order to achieve rapid extraction and modeling of power lines in substations, this paper proposes a method of power line extraction and modeling based on three-dimensional (3D) laser scanning point cloud da...
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Article
Open AccessResearch progresses of nanomaterials as lubricant additives
Friction and wear are unavoidable in mechanical movement. The use of lubricants with nano-additives can effectively reduce friction and wear, which is of great significance to saving energy and protecting the ...
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Article
CYTOR-NFAT1 feedback loop regulates epithelial-mesenchymal transition of retinal pigment epithelial cells
Epithelial mesenchymal transition (EMT) occurring in retinal pigment epithelial cells (RPE) is a crucial mechanism that contributes to the development of age-related macular degeneration (AMD), a pivotal facto...
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Joint radiomics and spatial distribution model for MRI-based discrimination of multiple sclerosis, neuromyelitis optica spectrum disorder, and myelin-oligodendrocyte-glycoprotein-IgG-associated disorder
To develop a discrimination pipeline concerning both radiomics and spatial distribution features of brain lesions for discrimination of multiple sclerosis (MS), aquaporin-4-IgG-seropositive neuromyelitis optic...
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Article
A small-molecule activation mechanism that directly opens the KCNQ2 channel
Pharmacological activation of voltage-gated ion channels by ligands serves as the basis for therapy and mainly involves a classic gating mechanism that augments the native voltage-dependent open probability. T...
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Article
Nonreciprocal thermal metamaterials: Methods and applications
Nonreciprocity of thermal metamaterials has significant application prospects in isolation protection, unidirectional transmission, and energy harvesting. However, due to the inherent isotropic diffusion law o...
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Open AccessAssociation Between Myopia and Pupil Diameter in Preschoolers: Evidence from a Machine Learning Approach Based on a Real-World Large-Scale Dataset
Previous studies have explored the connections between various ocular biological parameters with myopia. Our previous study also found that pupil data can predict the myopic progression during the intervention...
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Article
Coordinate-wise monotonic transformations enable privacy-preserving age estimation with 3D face point cloud
The human face is a valuable biomarker of aging, but the collection and use of its image raise significant privacy concerns. Here we present an approach for facial data masking that preserves age-related featu...
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Article
Quantifying the Importance of Non-Suicidal Self-Injury Characteristics in Predicting Different Clinical Outcomes: Using Random Forest Model
Existing research on non-suicidal self-injury (NSSI) among adolescents has primarily concentrated on general risk factors, leaving a significant gap in understanding the specific NSSI characteristics that pred...
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The influence of gender-specific factors influencing severe anxiety in psychotic major depression: role of thyroid hormones and depression severity
Psychotic major depression (PMD) is characterized by major depressive disorder (MDD) accompanied by delusions or hallucinations. While the prevalence of PMD and its association with anxiety have been studied, ...
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Article
Bi2S3 nanofiber bunch for highly efficient CO2 electroreduction to formate at low overpotential
Electrochemical conversion of CO2 into valuable chemicals represents a promising strategy to alleviate the environmental issues caused by excessive CO2 levels in the atmosphere. In this work, Bi2S3 with different...
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Comparative Study on the Cleanliness and Mechanical Properties of a Cast and Wrought Ni-Based Superalloy GH4738 Prepared with Revert Addition
Superalloy recycling is recognized as an economic and strategic necessity, but very little quantitative information is available regarding the criterion for operating, including the recycling procedure, the pe...