11 Result(s)
within
**ao-yan Cheng
Biomedicine
Oncology
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Article
Open AccessA specific tRNA half, 5’tiRNA-His-GTG, responds to hypoxia via the HIF1α/ANG axis and promotes colorectal cancer progression by regulating LATS2
Currently, tRNA-derived small RNAs (tsRNAs) are recognized as a novel and potential type of non-coding RNAs (ncRNAs), which participate in various cellular processes and play an essential role in cancer progre...
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Article
Open AccessDevelo** and validating an integrated gross tumor volume (GTV)-TNM stratification system for supplementing unresectable locally advanced non-small cell lung cancer treated with concurrent chemoradiotherapy
The gross tumor volume (GTV) could be an independent prognostic factor for unresectable locally advanced non-small cell lung cancer (LANSCLC). We aimed to develop and validate a novel integrated GTV-TNM strati...
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Article
Open AccessSignaling protein signature predicts clinical outcome of non-small-cell lung cancer
Non-small-cell lung cancer (NSCLC) is characterized by abnormalities of numerous signaling proteins that play pivotal roles in cancer development and progression. Many of these proteins have been reported to b...
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Article
Open AccessPlatinum sensitivity and CD133 expression as risk and prognostic predictors of central nervous system metastases in patients with epithelial ovarian cancer
To characterize prognostic and risk factors of central nervous system (CNS) metastases in patients with epithelial ovarian cancer (EOC).
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Article
Open AccessIncreased incidence of head and neck cancer in liver transplant recipients: a meta-analysis
It is unclear whether liver transplantation is associated with an increased incidence of post-transplant head and neck cancer. This comprehensive meta-analysis evaluated the association between liver transplan...
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Article
Open AccessDown-regulation of sirtuin 3 is associated with poor prognosis in hepatocellular carcinoma after resection
Sirtuin 3 (Sirt3), one of the seven Sirtuins family members, plays critical roles in the progression of multiple cancer types. However, its role in the prognosis of hepatocellular carcinoma (HCC) has not yet b...
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Open AccessClinical significance and gene expression study of human hepatic stellate cells in HBV related-hepatocellular carcinoma
Peritumoral activated hepatic stellate cells (HSCs) are versatile myofibroblast-like cells closely related with hepatocellular carcinoma (HCC) progression. So far, comprehensive comparison of gene expression o...
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Article
Calpain, Atg5 and Bak play important roles in the crosstalk between apoptosis and autophagy induced by influx of extracellular calcium
Calcium (Ca2+) signals are involved in important checkpoints in cell death pathways and promote both apoptosis and autophagy. However, the relationship between autophagy and apoptosis in response to Ca2+ level el...
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Article
Open AccessA pri-miR-218variant and risk of cervical carcinoma in Chinese women
MicroRNA (miRNA)-related single nucleotide polymorphisms (SNPs) may compromise miRNA binding affinity and modify mRNA expression levels of the target genes, thus leading to cancer susceptibility. However, few ...
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Article
Open AccessHigh expression of IL-17 and IL-17RE associate with poor prognosis of hepatocellular carcinoma
Hepatocellular carcinoma (HCC) is a typical malignancy in a background of chronic inflammation. Th17 cells (a major source of IL-17) constitute crucial components of infiltrating inflammatory/immune cells in H...
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Article
Frequent loss of membranous E-cadherin in gastric cancers: A cross-talk with Wnt in determining the fate of β-catenin
The potential correlation of E-cadherin reduction and Wnt2 up-regulation in determining the intracellular distribution of β-catenin in gastric cancers was investigated by the methods of frozen tissue array-bas...
