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Article
Adaptation of a prey population to increasing predation risks
To test the hypotheses that multigenerational predation risk favors clones with longer postero-lateral spines and a larger body, and that fitness consequences of selection depend on both tested fitness variabl...
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Article
Open AccessComprehensive meta-analysis of severe fever with thrombocytopenia syndrome virus infections in humans, vertebrate hosts and questing ticks
Severe fever with thrombocytopenia syndrome (SFTS) is an emerging tick-borne zoonosis caused by the SFTS virus (SFTSV). Understanding the prevalence of SFTSV RNA in humans, vertebrate hosts and ticks is crucia...
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Article
Bio-mediated geotechnology and its application in geoengineering: mechanism, approach, and performance
Bio-mediated geotechnology refers to the technology that utilizes various types of microbial processes to improve the hydro-mechanical behavior of soil and rock, aiming for the prevention and mitigation of geo...
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Article
Open AccessDevelopment and validation of a nomogram to predict postoperative delirium in older patients after major abdominal surgery: a retrospective case-control study
Postoperative delirium is a common complication in older patients, with poor long-term outcomes. This study aimed to investigate risk factors and develop a predictive model for postoperative delirium in older ...
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Article
Gastrodin Regulates PI3K/AKT-Sirt3 Signaling Pathway and Proinflammatory Mediators in Activated Microglia
Activated microglia and their mediated inflammatory responses play an important role in the pathogenesis of hypoxic-ischemic brain damage (HIBD). Therefore, regulating microglia activation is considered a pote...
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Article
Single transition-metal atoms anchored on a novel Dirac-dispersive π-π conjugated holey graphitic carbon nitride substrate: computational screening toward efficient bifunctional OER/ORR electrocatalysts
Nonprecious-metal-group single-metal-atom catalysts with bifunctional catalytic capabilities toward the oxygen evolution reaction (OER) and oxygen reduction reaction (ORR) are highly sought after in energy-con...
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Article
Open AccessPhotooxidation triggered ultralong afterglow in carbon nanodots
It remains a challenge to obtain biocompatible afterglow materials with long emission wavelengths, durable lifetimes, and good water solubility. Herein we develop a photooxidation strategy to construct near-in...
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Article
Open AccessMulti-modal molecular determinants of clinically relevant osteoporosis subtypes
Due to a rapidly aging global population, osteoporosis and the associated risk of bone fractures have become a wide-spread public health problem. However, osteoporosis is very heterogeneous, and the existing s...
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Article
Elemene Antitumor Drugs Development Based on “Molecular Compatibility Theory” and Clinical Application: A Retrospective and Prospective Outlook
Elemene, derived from Curcuma wenyu**, one of the “8 famous genuine medicinal materials of Zhejiang province,” exhibits remarkable antitumor activity. It has gained wide recognition in clinical practice for effe...
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Article
Risk stratification of gallbladder masses by machine learning-based ultrasound radiomics models: a prospective and multi-institutional study
This study aimed to evaluate the diagnostic performance of machine learning (ML)–based ultrasound (US) radiomics models for risk stratification of gallbladder (GB) masses.
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Article
Dynamic evaluation of a scaled-down heat pipe-cooled system during start-up/shut-down processes using a hardware-in-the-loop test approach
Micro-mobile heat pipe-cooled nuclear power plants are promising candidates for distributed energy resource power generators and can be flexibly deployed in remote places to meet increasing electric power dema...
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Article
Open AccessSingle-cell and spatial architecture of primary liver cancer
Primary liver cancer (PLC) poses a leading threat to human health, and its treatment options are limited. Meanwhile, the investigation of homogeneity and heterogeneity among PLCs remains challenging. Here, usi...
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Article
Numerical and theoretical investigations of heat transfer characteristics in helium–xenon cooled microreactor core
Helium–xenon cooled microreactors are a vital technological solution for portable nuclear reactor power sources. To examine the convective heat transfer behavior of helium–xenon gas mixtures in a core environm...
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Article
Open AccessA model based on adipose and muscle-related indicators evaluated by CT images for predicting microvascular invasion in HCC patients
The presence of microvascular invasion (MVI) will impair the surgical outcome of hepatocellular carcinoma (HCC). Adipose and muscle tissues have been confirmed to be associated with the prognosis of HCC. We ai...
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Article
Open AccessResearch on the development methodology for clinical practice guidelines for organic integration of traditional Chinese and Western medicine
Integrated traditional Chinese medicine (TCM) and Western medicine (WM) is a new medical science grounded in the knowledge bases of both TCM and WM, which then forms a unique modern medical system in China. In...
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Article
Open AccessValue of Echocardiography and Cardiac Magnetic resonance in assessing left ventricular function in breast and gastric cancer patients after Anthracycline Chemotherapy
Echocardiography (ECHO) and cardiac magnetic resonance imaging (MRI) are used to observe changes in the left ventricular structure in patients with breast and gastric cancer after 6 cycles of chemotherapy. Bas...
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Article
Open AccessXrvB regulates the type III secretion system by directly repressing hrpG transcription in Xanthomonas oryzae pv. oryzicola
Xrv proteins are a group of regulators in Xanthomonas spp., belonging to the histone-like nucleoid-structuring (H-NS) proteins of Gram-negative bacteria. The rice bacterial leaf streak pathogen Xanthomonas oryzae
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Article
Open AccessIndividual bat virome analysis reveals co-infection and spillover among bats and virus zoonotic potential
Bats are reservoir hosts for many zoonotic viruses. Despite this, relatively little is known about the diversity and abundance of viruses within individual bats, and hence the frequency of virus co-infection a...
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Article
The role of ultrasound in screening subclinical psoriatic arthritis in patients with moderate to severe psoriasis
To identify patients in the subclinical psoriatic arthritis (Sub-PsA) phase by ultrasound (US) and provide a solution to screen them.
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Article
Modular divergent creation of dual-cocatalysts integrated semiconducting sulfide nanotriads for enhanced photocatalytic hydrogen evolution
Heteronanostructures (HNs) with precise components and interfaces are important for many applications, such as designing efficient and robust solar-to-fuel catalysts via integrating specific semiconductors wit...
