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Article
Open AccessCrosstalk among proximal tubular cells, macrophages, and fibroblasts in acute kidney injury: single-cell profiling from the perspective of ferroptosis
The link between ferroptosis, a form of cell death mediated by iron and acute kidney injury (AKI) is recently gaining widespread attention. However, the mechanism of the crosstalk between cells in the pathogen...
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Article
Open AccessTMC6 functions as a GPCR-like receptor to sense noxious heat via Gαq signaling
Thermosensation is vital for the survival, propagation, and adaption of all organisms, but its mechanism is not fully understood yet. Here, we find that TMC6, a membrane protein of unknown function, is highly ...
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Article
Experimental Study of the Discharge Characteristics of a Stepped-Nozzle Arc Plasma Torch
The stepped-nozzle arc plasma torch (SNAPT) is a promising arc source due to the advantages of high stability and high energy density, but the micro-time scale discharge characteristics have not yet been adequ...
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Article
Bio-mediated geotechnology and its application in geoengineering: mechanism, approach, and performance
Bio-mediated geotechnology refers to the technology that utilizes various types of microbial processes to improve the hydro-mechanical behavior of soil and rock, aiming for the prevention and mitigation of geo...
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Article
Open AccessMorphology characterization of unsaturated soils under drying-wetting cycles: crack opening and closure
The volumetric and hydrological responses of clayey soils subjected to drying-wetting (D-W) cycles are of paramount importance for the integrity of geoenvironmental infrastructures. The study aimed to investig...
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Article
Open AccessCe6-modified Fe ions-doped carbon dots as multifunctional nanoplatform for ferroptosis and photodynamic synergistic therapy of melanoma
Despite the higher sensitivity of melanoma towards ferroptosis and photodynamic therapy (PDT), the lack of efficient ferroptosis inducers and the poor solubility of photosensitizers restrict their synergistic ...
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Article
Open AccessLight-field flow cytometry for high-resolution, volumetric and multiparametric 3D single-cell analysis
Imaging flow cytometry (IFC) combines flow cytometry and fluorescence microscopy to enable high-throughput, multiparametric single-cell analysis with rich spatial details. However, current IFC techniques remai...
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Article
The Identification of Gamma-Glutamyl Hydrolase in Uterine Corpus Endometrial Carcinoma: a Predictive Model and Machine Learning
Poor neoplastic differentiation contributes to the rapid progression of uterine corpus endometrial carcinoma (UCEC). Thus, it is essential to identify candidate genes, clarifying the carcinogenesis and progres...
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Article
Open AccessA novel anoikis-related gene signature predicts prognosis in patients with sepsis and reveals immune infiltration
Sepsis is a common acute and severe medical condition with a high mortality rate. Anoikis, an emerging form of cell death, plays a significant role in various diseases. However, the role of anoikis in sepsis r...
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Article
Deep learning for virtual orthodontic bracket removal: tool establishment and application
We aimed to develop a tool for virtual orthodontic bracket removal based on deep learning algorithms for feature extraction from bonded teeth and to demonstrate its application in a bracket position assessment...
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Article
Open AccessCirculating blood biomarkers correlated with the prognosis of advanced triple negative breast cancer
Immune checkpoint inhibitors (ICIs) can improve survivals of metastatic triple negative breast cancer (mTNBC); however, we still seek circulating blood biomarkers to predict the efficacy of ICIs.
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Article
Experimental study on shrinkage characteristics of compacted bentonite–sand mixtures
Bentonite–sand mixtures have been proposed as the potential engineered barrier materials because of their low permeability and strong sealing ability under hydrated repository conditions. However, the mixtures...
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Chapter and Conference Paper
PoShapley-BCFL: A Fair and Robust Decentralized Federated Learning Based on Blockchain and the Proof of Shapley-Value
Recently, blockchain-based Federated learning (BCFL) has emerged as a promising technology for promoting data sharing in the Internet of Things (IoT) without relying on a central authority, while ensuring data...
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Article
Characterization and quantification of calcite distribution in MICP-treated sand using μ-XRF image processing technique
A new approach integrating micro X-ray fluorescence (μ-XRF) and digital image processing is proposed to quantify the spatial distribution of calcium carbonate crystals for microbial-induced calcite precipitati...
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Article
Improved fatigue behaviour of perovskite solar cells with an interfacial starch–polyiodide buffer layer
Metal halide perovskite solar cells are expected to lead the revolution in photovoltaics. However, due to their soft and ionic lattice, perovskites are sensitive to external stimuli, and the resulting devices ...
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Article
Serum THBS2 is a potential biomarker for the diagnosis of non-small cell lung cancer
This study primarily aimed to analyze the levels of THBS2 in the serum of patients diagnosed with non-small cell lung cancer (NSCLC), and subsequently evaluate its potential as a diagnostic biomarker for NSCLC.
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Article
Monitoring and map** the evolution of clayey soil desiccation cracking using electrical resistivity tomography
Drought-induced clayey soil desiccation cracking is a common natural phenomenon. The presence of cracks can significantly alter the mechanical and hydraulic properties of clayey soils, and cause a series of en...
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Article
TGR: Neural-symbolic ontological reasoner for domain-specific knowledge graphs
Ontological reasoning has great prospects in applications based on domain-specific knowledge graphs (KG). However, it is difficult for existing logic reasoners to quickly perform inference over large-scale ass...
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Article
Open AccessMesenchymal stromal/stem cells and their extracellular vesicles in liver diseases: insights on their immunomodulatory roles and clinical applications
Liver disease is a leading cause of mortality and morbidity that is rising globally. Liver dysfunctions are classified into acute and chronic diseases. Various insults, including viral infections, alcohol or d...
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Article
Current Situation of Agricultural Non-Point Source Pollution and Its Control
Agricultural non-point source pollution (AGNPS) is considered a key problem affecting global water quality. The main causes of AGNPS are the loss of N, P, and other pollutants in agricultural production activi...
