513 Result(s)

Article

LABS: linear amplification-based bisulfite sequencing for ultrasensitive cancer detection from cell-free DNA

Methylation-based liquid biopsies show promises in detecting cancer using circulating cell-free DNA; however, current limitations impede clinical application. Most assays necessitate substantial DNA inputs, po...

**ao-Long Cui, Ji Nie, Houxiang Zhu, Krissana Kowitwanich… in Genome Biology (2024)

Article

Comparative transcriptome analysis reveals genes involved in trichome development and metabolism in tobacco

The glandular trichomes of tobacco (Nicotiana tabacum) can efficiently produce secondary metabolites. They act as natural bioreactors, and their natural products function to protect plants against insect-pests an...

Mingli Chen, Zhiyuan Li, **nxi He, Zhe Zhang, Dong Wang, Luying Cui… in BMC Plant Biology (2024)

Article

Revealing critical mechanisms in determining sorghum resistance to drought and salt using mRNA, small RNA and degradome sequencing

Plant growth and development are severely threatened by drought and salt stresses. Compared with structural genes, transcription factors (TFs) play more pivotal roles in plant growth and stress adaptation. How...

Qiong Li, Jibin Wang, Qian Liu, Junhan Zhang, **nlei Zhu, Yinpeng Hua… in BMC Plant Biology (2024)

Article

Genome-wide identification and expression analysis of the KNOX family and its diverse roles in response to growth and abiotic tolerance in sweet potato and its two diploid relatives

KNOXs, a type of homeobox genes that encode atypical homeobox proteins, play an essential role in the regulation of growth and development, hormonal response, and abiotic stress in plants. However, the KNOX gene ...

Li-Cong Jia, Zi-Tong Yang, Li-Li Shang, Shao-Zhen He, Huan Zhang, Xu Li… in BMC Genomics (2024)

Article

Leptin receptor neurons in the ventral premammillary nucleus modulate emotion-induced insomnia

**ang-shan Yuan, Zhe **ang, Jian-bo Jiang, Fang Yuan, Mu-tian Zhang… in Cell Discovery (2024)

Article

Genome-wide identification and investigation of monosaccharide transporter gene family based on their evolution and expression analysis under abiotic stress and hormone treatments in maize (Zea mays L.)

Monosaccharide transporter (MST) family, as a carrier for monosaccharide transport, plays an important role in carbon partitioning and widely involves in plant growth and development, stress response, and sign...

Jialun Zhu, Tianfeng Li, **g Ma, Wenyu Li, Hanyu Zhang… in BMC Plant Biology (2024)

Article

Adaptation mechanism of three Impatiens species to different habitats based on stem morphology, lignin and MYB4 gene

Impatiens is an important genus with rich species of garden plants, and its distribution is extremely extensive, which is reflected in its diverse ecological environment. However, the specific mechanisms of Impat...

**n-Yi Li, Ze-Feng Li, **ao-Li Zhang, Meng-Qing Yang, Pei-Qing Wu… in BMC Plant Biology (2024)

Article

HAP40 modulates mutant Huntingtin aggregation and toxicity in Huntington’s disease mice

Huntington’s disease (HD) is a monogenic neurodegenerative disease, caused by the CAG trinucleotide repeat expansion in exon 1 of the Huntingtin (HTT) gene. The HTT gene encodes a large protein known to interact ...

Laiqiang Chen, Yiyang Qin, Tingting Guo, Wenzhen Zhu, **gpan Lin… in Cell Death & Disease (2024)

Article

NLRP4E regulates actin cap formation through SRC and CDC42 during oocyte meiosis

Members of the nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing (NLRP) family regulate various physiological and pathological processes. However, none have been shown ...

Li-Ya Shi, Yang Wang, Yan-Jie Yang, Qian Li… in Cellular & Molecular Biology Letters (2024)

Article

Identification and characterization of PAL genes involved in the regulation of stem development in Saccharum spontaneum L.

Saccharum spontaneum L. is a closely related species of sugarcane and has become an important genetic component of modern sugarcane cultivars. Stem development is one of the important factors for affecting the yi...

**aoqing Wu, Zetian Cui, **nyi Li, Zehuai Yu, **** Lin, Li Xue… in BMC Genomic Data (2024)

Article

Genome-wide characterization of DNA methyltransferase family genes implies GhDMT6 improving tolerance of salt and drought on cotton

DNA methylation is an important epigenetic mode of genomic DNA modification and plays a vital role in maintaining epigenetic content and regulating gene expression. Cytosine-5 DNA methyltransferase (C5-MTase) are...

**aomin Yang, Zhigang Bai, Yunxin He, Ning Wang, Liangqing Sun… in BMC Plant Biology (2024)

Article

Elongin B promotes breast cancer progression by ubiquitinating tumor suppressor p14/ARF

Elongin B (ELOB), a pivotal element in the ELOB/c-Cullin2/5-SOCS-box E3 ubiquitin-protein ligase complex, plays a significant role in catalyzing the ubiquitination and subsequent degradation of a broad spectru...

**n-Yi Sui, **ao-Yan Ma, Yu** Hou, Shuo-Wen Cao… in Cell Biology and Toxicology (2024)

Article

Genome-wide identification and expression pattern analysis of the Aux/IAA (auxin/indole-3-acetic acid) gene family in alfalfa (Medicago sativa) and the potential functions under drought stress

Auxin/induced-3-acetic acid (Aux/IAA) is an important plant hormone that affects plant growth and resistance to abiotic stresses. Drought stress is a vital factor in reducing plant biomass yield and production...

**qing Zhang, Shuxia Li, Xueqin Gao, Yaling Liu, BingZhe Fu in BMC Genomics (2024)

Article

TIP aquaporins in Cyperus esculentus: genome-wide identification, expression profiles, subcellular localizations, and interaction patterns

Tonoplast intrinsic proteins (TIPs), which typically mediate water transport across vacuolar membranes, play an essential role in plant growth, development, and stress responses. However, their characterizatio...

Zhi Zou, Yujiao Zheng, Lili Chang, Liang** Zou, Li Zhang, Yi Min… in BMC Plant Biology (2024)

Article

Csn5 inhibits autophagy by regulating the ubiquitination of Atg6 and Tor to mediate the pathogenicity of Magnaporthe oryzae

Csn5 is subunit 5 of the COP9 signalosome (CSN), but the mechanism by which it strictly controls the pathogenicity of pathogenic fungi through autophagy remains unclear. Here, we found that Csn5 deficiency att...

Zi-Fang Shen, Lin Li, **g-Yi Wang, Jian Liao… in Cell Communication and Signaling (2024)