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398 Result(s)
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Article
Homologous heterostructure of MoS2 and MoO2 coupled with carbon layers as cathode catalyst for rechargeable lithium–oxygen batteries
Lithium–oxygen batteries tend to experience high overpotentials because of the sluggish oxygen reduction reaction and oxygen evolution reaction during cycling. A potential solution to address this issue is to ...
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Article
Open AccessIdentification and bioinformatics analysis of genes associated with pyroptosis in spinal cord injury of rat and mouse
The mechanism of spinal cord injury (SCI) is highly complex, and an increasing number of studies have indicated the involvement of pyroptosis in the physiological and pathological processes of secondary SCI. H...
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Article
Open AccessChiral dinitrogen ligand enabled asymmetric Pd/norbornene cooperative catalysis toward the assembly of C–N axially chiral scaffolds
C − N axially chiral compounds have recently attracted significant interest among synthetic chemistry community due to their widespread application in pharmaceuticals, advanced materials and organic synthesis....
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Article
Open AccessDevelopment of Vogt–Koyanagi–Harada disease-like uveitis during treatment by anti-programmed death-1 antibody: a case report
Several immune checkpoint inhibitors (ICIs) have been linked to the occurrence of Vogt-Koyanagi-Harada disease (VKHD)-like uveitis. Among the ICIs, there has been no report of immune-related adverse events (ir...
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Article
Open AccessOliTag-seq enhances in cellulo detection of CRISPR-Cas9 off-targets
The potential for off-target mutations is a critical concern for the therapeutic application of CRISPR-Cas9 gene editing. Current detection methodologies, such as GUIDE-seq, exhibit limitations in oligonucleot...
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Article
Study on tungsten sintering temperature field based on electromagnetic simulation and computational fluid dynamics
In order to study the influence of various sintering variables more intuitively and clearly, electromagnetic field analysis and computational fluid dynamics are used to analyze the influence of gas flow, heati...
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Article
Global H. pylori recurrence, recrudescence, and re-infection status after successful eradication in pediatric patients: a systematic review and meta-analysis
Little information is available regarding global H. pylori recurrence, recrudescence, and re-infection in pediatric patients after successful eradication, nor are their influencing factors clear. We conducted a s...
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Article
Open AccessSpatial transcriptomics reveals gene interactions and signaling pathway dynamics in rat embryos with anorectal malformation
Anorectal malformation (ARM) is a prevalent early pregnancy digestive tract anomaly. The intricate anatomy of the embryonic cloaca region makes it challenging for traditional high-throughput sequencing methods...
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Article
HDAC inhibitors as a potential therapy for chemotherapy-induced neuropathic pain
Cancer, a chronic disease characterized by uncontrolled cell development, kills millions of people globally. The WHO reported over 10 million cancer deaths in 2020. Anticancer medications destroy healthy and m...
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Article
Preparation and gas sensing properties of hexagonal zinc oxide regulated by surface modification
Hexagonal ZnO nanocones were successfully synthesized by hydrothermal method, combined with active agents and other means of control, and calcined at 350 °C. Detailed testing and research were conducted on the...
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Article
Clinicopathological characteristics and prognosis of Epstein-Barr virus–associated gastric cancer
Epstein-Barr virus (EBV)-associated gastric cancer (EBVaGC) is a distinct molecular subtype of gastric cancer (GC). At present, the clinical characteristics and prognostic implications of EBV infection and the...
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Article
Open AccessA non-image-forming visual circuit mediates the innate fear of heights in male mice
The neural basis of fear of heights remains largely unknown. In this study, we investigated the fear response to heights in male mice and observed characteristic aversive behaviors resembling human height vert...
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Article
Characteristics and literature review of ETV6::ABL1 fusion gene-positive acute myeloid leukemia
To describe the features of ETV6::ABL1 AML as well as the clinical treatment and outcomes.
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Article
Creation of memory–memory entanglement in a metropolitan quantum network
Towards realizing the future quantum internet1,2, a pivotal milestone entails the transition from two-node proof-of-principle experiments conducted in laboratories to comprehensive multi-node set-ups on large sca...
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Article
Excitotoxic Storms of Ischemic Stroke: A Non-neuronal Perspective
Numerous neurological disorders share a fatal pathologic process known as glutamate excitotoxicity. Among which, ischemic stroke is the major cause of mortality and disability worldwide. For a long time, the m...
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Article
Cpd-A1 alleviates acute kidney injury by inhibiting ferroptosis
Acute kidney injury (AKI) is defined as sudden loss of renal function characterized by increased serum creatinine levels and reduced urinary output with a duration of 7 days. Ferroptosis, an iron-dependent reg...
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Article
Influence of heat treatment on microstructure of a new β-solidifying γ-TiAl alloy
The high strength and stability of the full-lamellar structure guarantee the industrial application of the β-solidifying γ-TiAl alloys. However, it is a huge challenge to design an alloy with good hot-deformab...
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Article
Three-Dimensional Sound Source Location Algorithm for Subsea Leakage Using Hydrophone
Leakages from subsea oil and gas equipment cause substantial economic losses and damage to marine ecosystem, so it is essential to locate the source of the leak. However, due to the complexity and variability ...
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Article
In vivo ultrasound-induced luminescence molecular imaging
Optical imaging is crucial to study biological or pathological processes and diagnose diseases. However, poor tissue penetration typically limits conventional optical imaging. Here we report an imaging techniq...
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Article
Effects of New Psychoactive Substance Esketamine on Behaviors and Transcription of Genes in Dopamine and GABA Pathways in Zebrafish Larvae
Esketamine (ESK) is the S-enantiomer of ketamine racemate (a new psychoactive substance) that can result in illusions, and alter hearing, vision, and proprioception in human and mouse. Up to now, the neurotoxicit...