-
Article
Open AccessMOC1 cleaves Holliday junctions through a cooperative nick and counter-nick mechanism mediated by metal ions
Holliday junction resolution is a crucial process in homologous recombination and DNA double-strand break repair. Complete Holliday junction resolution requires two stepwise incisions across the center of the ...
-
Article
Open AccessAltered chromatin topologies caused by balanced chromosomal translocation lead to central iris hypoplasia
Despite the advent of genomic sequencing, molecular diagnosis remains unsolved in approximately half of patients with Mendelian disorders, largely due to unclarified functions of noncoding regions and the diff...
-
Article
Open AccessLongitudinal viral shedding and antibody response characteristics of men with acute infection of monkeypox virus: a prospective cohort study
Understanding of infection dynamics is important for public health measures against monkeypox virus (MPXV) infection. Herein, samples from multiple body sites and environmental fomites of 77 acute MPXV infecti...
-
Article
Influence of 3D Aggregate Shape on the Meso-Structure of 2D Cross-Sectional Concrete by the Numerical Slicing Method
Aggregate shape is essential for evaluating concrete properties. Most of the existing literature utilizes X-ray computed tomography (X-CT) to assess the morphological characteristics of 2D/3D aggregates. Howev...
-
Article
Open AccessUltrastable halide perovskite CsPbBr3 photoanodes achieved with electrocatalytic glassy-carbon and boron-doped diamond sheets
Halide perovskites exhibit exceptional optoelectronic properties for photoelectrochemical production of solar fuels and chemicals but their instability in aqueous electrolytes hampers their application. Here w...
-
Article
Open AccessSpatial patterns of Holocene temperature changes over mid-latitude Eurasia
The Holocene temperature conundrum, the discrepancy between proxy-based Holocene global cooling and simulated global annual warming trends, remains controversial. Meanwhile, reconstructions and simulations sho...
-
Article
Open AccessPROST: quantitative identification of spatially variable genes and domain detection in spatial transcriptomics
Computational methods have been proposed to leverage spatially resolved transcriptomic data, pinpointing genes with spatial expression patterns and delineating tissue domains. However, existing approaches fall...
-
Article
Open AccessElectrically and mechanically driven rotation of polar spirals in a relaxor ferroelectric polymer
Topology created by quasi-continuous spatial variations of a local polarization direction represents an exotic state of matter, but field-driven manipulation has been hitherto limited to creation and destructi...
-
Article
Open AccessPrediction of lithium-ion battery SOC based on the fusion of MHA and ConvolGRU
If the charging state of the lithium-ion battery can be accurately predicted, overcharge and overdischarge of the battery can be avoided, and the service life of the battery can be improved. In order to improv...
-
Article
Open AccessUnraveling bilayer interfacial features and their effects in polar polymer nanocomposites
Polymer nanocomposites with nanoparticles dispersed in polymer matrices have attracted extensive attention due to their significantly improved overall performance, in which the nanoparticle-polymer interface p...
-
Article
Open AccessChromosome-level genome assembly and annotation of the prickly nightshade Solanum rostratum Dunal
The prickly nightshade Solanum rostratum, an annual malignant weed, is native to North America and has globally invaded 34 countries, causing serious threats to ecosystems, agriculture, animal husbandry, and huma...
-
Article
Open AccessA DNA tumor virus globally reprograms host 3D genome architecture to achieve immortal growth
Epstein-Barr virus (EBV) immortalization of resting B lymphocytes (RBLs) to lymphoblastoid cell lines (LCLs) models human DNA tumor virus oncogenesis. RBL and LCL chromatin interaction maps are compared to ide...
-
Article
Open AccessInvestigation of the acoustic emission and fractal characteristics of coal with varying water contents during uniaxial compression failure
To investigate the effect of water on the mechanical properties and acoustic emission (AE) characteristics of coal in the failure and deformation processes. Coal samples of different content were subjected to ...
-
Article
Open AccessClassification of rice leaf blast severity using hyperspectral imaging
Rice leaf blast is prevalent worldwide and a serious threat to rice yield and quality. Hyperspectral imaging is an emerging technology used in plant disease research. In this study, we calculated the standard ...
-
Article
Open AccessA study on moment tensor inversion of acoustic emission response on damaging localization of gas-bearing coal under load
During the deformation and fracture process, the acoustic emission (AE) signals can be produced for the of coal, rock and other solid materials, which revealing the damage localization evolution process. The e...
-
Article
Influence of Drill String Size on Hydraulic Elongation Limit of Extended Reach Wells-Taking Well X in Bohai Oilfield as an Example
Accurate prediction of extension limit of extended-reach well is of great significance for safe drilling. Hydraulic extension limit is an important part of the extended reach wells design. In this paper, the b...
-
Article
Open AccessNon-stationary time-varying vehicular channel characteristics for different roadside scattering environments
With the deep integration of wireless communication technology and automobile industry, vehicular communication has become one of the key technologies supporting the development of Internet-of-vehicle. Due to ...
-
Article
Open AccessLanthanum nitrate as aqueous electrolyte additive for favourable zinc metal electrodeposition
Aqueous zinc batteries are appealing devices for cost-effective and environmentally sustainable energy storage. However, the zinc metal deposition at the anode strongly influences the battery cycle life and pe...
-
Article
Open AccessAssociation of physical activity and positive thinking with global sleep quality
This study examined the association of different intensity levels of physical activity and positive thinking with a global sleep quality among college students. The research question was: to what degree were t...
-
Article
Open AccessGlobal warming-induced Asian hydrological climate transition across the Miocene–Pliocene boundary
Across the Miocene–Pliocene boundary (MPB; 5.3 million years ago, Ma), late Miocene cooling gave way to the early-to-middle Pliocene Warm Period. This transition, across which atmospheric CO2 concentrations incre...