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Article
Open AccessA survey in rural China of parent-absence through migrant working: the impact on their children's self-concept and loneliness
Following the rapid increase of migrant workers in China, the number of "absent migrant parents" children is also rising fast. The "absent migrant parents" children might have an insecure relationship with the...
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Article
Open AccessImpact of glycemic control on circulating endothelial progenitor cells and arterial stiffness in patients with type 2 diabetes mellitus
Patients with type 2 diabetes mellitus (DM) have increased risk of endothelial dysfunction and arterial stiffness. Levels of circulating endothelial progenitor cells (EPCs) are also reduced in hyperglycemic st...
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Article
Open AccessClinical significance of combined detection of human papilloma virus infection and human telomerase RNA component gene amplification in patients with squamous cell carcinoma of the esophagus in northern China
The aim of the study was to test for human papilloma virus (HPV) infection and human telomerase RNA component (hTERC) gene amplification in tissues derived from esophageal cancer, in esophagus displaying atypi...
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Article
Open AccessRole of berberine in anti-bacterial as a high-affinity LPS antagonist binding to TLR4/MD-2 receptor
Berberine is an isoquinoline alkaloid mainly extracted from Rhizoma Coptidis and has been shown to possess a potent inhibitory activity against bacterial. However, the role of berberine in anti-bacterial action h...
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Article
Open AccessEvaluation and clinical significance of the stomach age model for evaluating aging of the stomach-a multicenter study in China
A higher prevalence of chronic atrophic gastritis (CAG) occurs in younger adults in Asia. We used Stomach Age to examine the different mechanisms of CAG between younger adults and elderly individuals, and esta...
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Article
Open AccessTraditional Chinese medicine for stable angina pectoris via TCM pattern differentiation and TCM mechanism: study protocol of a randomized controlled trial
Stable angina pectoris is experienced as trans-sternal or retro-sternal pressure or pain that may radiate to the left arm, neck or back. Although available evidence relating to its effectiveness and mechanism ...
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Article
Open AccessThe effects of Cordyceps sinensis phytoestrogen on estrogen deficiency-induced osteoporosis in Ovariectomized rats
Isoflavones are naturally occurring plant chemicals belonging to the “phytoestrogen” class. The aim of the present study was to examine the effects of isoflavones obtained from Cordyceps sinensis (CSIF) on develo...
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Article
Open AccessAssociation between polymorphisms in the estrogen receptor alpha gene and osteoarthritis susceptibility: a meta-analysis
Osteoarthritis (OA) is a common chronic disease of the joints. Genetic factors may play a role in its development, and polymorphisms in the estrogen receptor alpha gene (ERα) have been associated with OA. However...
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Article
Open AccessThe influence of body composition on the N-terminal pro-B-type natriuretic peptide level and its prognostic performance in patients with acute coronary syndrome: a cohort study
Whether body composition is associated with the N-terminal pro-B-type natriuretic peptide (NT-proBNP) level and its prognostic performance in acute coronary syndrome (ACS) remains unknown. We aimed to investig...
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Article
Open AccessIdentification of fetal cardiac anatomy and hemodynamics: a novel enhanced screening protocol
Prenatal cardiac screening is of great importance as it contributes to appropriate neonatal management and helps parents to make a decision regarding their pregnancy. The aim of our study was to evaluate the e...
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Article
Open AccessThe influence of body composition on renal function in patients with coronary artery disease and its prognostic significance: a retrospective cohort study
We try to analyse the effect of renal functions on death in CAD patients with different body compositions.
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Article
Open AccessVitamin D deficiency may predict a poorer outcome of IgA nephropathy
Experimental studies showed that 25-hydroxy-vitamin D [25(OH)D] deficiency (defined as 25-hydroxy-vitamin D < 15 ng/ml) has been associated with CKD progression. Patients with IgA nephropathy have an exception...
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Article
Open AccessDietary intake and risk of rheumatoid arthritis—a cross section multicenter study
Environmental factors play an important role in the development of rheumatoid arthritis (RA). Among these factors, smoking is generally considered to be an established risk factor for RA. Data regarding the im...
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Article
Open AccessElectroacupuncture for the prevention of postoperative gastrointestinal dysfunction in participants undergoing vascular laparotomy under general anesthesia: a randomized controlled trial
Postoperative gastrointestinal dysfunction (PGD) is a common complication following laparotomy under general anesthesia (GA). Abdominal distension occurs in 8–28% of surgeries within 24 h postoperatively. The ...
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Article
Open AccessEfficacy and safety of calcineurin inhibitor treatment for IgA nephropathy: a meta-analysis
IgA nephropathy is the most common progressive glomerular disease to end stage renal failure worldwide. Calcineurin inhibitors (CNIs) is a selective immunosuppressant widely used in organ transplantation. The ...
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Article
Open AccessA Review of the Novel Application and Potential Adverse Effects of Proton Pump Inhibitors
Proton pump inhibitors (PPIs) are known as a class of pharmaceutical agents that target H+/K+-ATPase, which is located in gastric parietal cells. PPIs are widely used in the treatment of gastric acid-related dise...
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Article
Open AccessAssociation between MPO-463G > A polymorphism and cancer risk: evidence from 60 case-control studies
Though a number of studies have been conducted to explore the association between myeloperoxidase (MPO)-463G > A polymorphism and cancer risk, the results remain inconsistent. Therefore, we performed a meta-an...
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Article
Open AccessTreatment and outcomes of tumor-induced osteomalacia associated with phosphaturic mesenchymal tumors: retrospective review of 12 patients
Tumor-induced osteomalacia (TIO) is a rare paraneoplastic syndrome characterized by severe hypophosphatemia and osteomalacia. Nonspecific symptoms make the diagnosis elusive. In addition, locating the responsi...
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Article
Open AccessThe prognostic value of T1 map** and late gadolinium enhancement cardiovascular magnetic resonance imaging in patients with light chain amyloidosis
Cardiac impairment is associated with high morbidity and mortality in immunoglobulin light chain (AL) type amyloidosis, for which early identification and risk stratification is vital. For myocardial tissue ch...
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Article
Correction to: Wnt/β-catenin signaling mediates the suppressive effects of diallyl trisulfide on colorectal cancer stem cells
Unfortunately, the online published article has error in Figure 4. The correct Figure 4 is given here.