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  1. Article

    Open Access

    A “twelve-section ultrasonic screening and diagnosis method” and management system for screening and treating neonatal congenital heart disease at the grassroots level in Tang County, Hebei Province, China

    To explore a method for screening and diagnosing neonatal congenital heart disease (CHD) applicable to grassroots level, evaluate the prevalence of CHD, and establish a hierarchical management system for CHD s...

    Yun Cui, **n-jian He, Le Wang, Yan-hui Fan, Jiao-yang Chen in BMC Pregnancy and Childbirth (2024)

  2. No Access

    Article

    Cancer-associated fibroblast exosomes promote prostate cancer metastasis through miR-500a-3p/FBXW7/HSF1 axis under hypoxic microenvironment

    Metastasis is the main cause of deaths in prostate cancer (PCa). However, the exact mechanisms underlying PCa metastasis are not fully understood. In this study, we discovered pronounced hypoxia in primary les...

    Zhanliang Liu, Zhemin Lin, Mingxin Jiang, Guangyi Zhu, Tianyu **ong in Cancer Gene Therapy (2024)

  3. No Access

    Article

    The effect of 5-α reductase inhibitor on Th1, Th2, and Th17 cell-related inflammatory response in BPH

    To investigate the effect of 5-α reductase inhibitor on the expression of inflammation-related cytokines in Benign prostatic hyperplasia (BPH) specimens after transurethral prostatic resection (TUR-P).

    Yifan Chu, Mengdong Zhang, Yun Cui, Dawei **e, Mingshuai Wang in World Journal of Urology (2023)

  4. No Access

    Article

    Microbiota-derived tryptophan catabolites mediate the chemopreventive effects of statins on colorectal cancer

    Epidemiological studies have indicated an association between statin use and reduced incidence of colorectal cancer (CRC), and work in preclinical models has demonstrated a potential chemopreventive effect. St...

    Ji-Xuan Han, Zhi-Hang Tao, Ji-Lin Wang, Lu Zhang, Chen-Yang Yu in Nature Microbiology (2023)

  5. Article

    Open Access

    MAPK4 silencing in gastric cancer drives liver metastasis by positive feedback between cancer cells and macrophages

    Liver metastasis is a major cause of death in gastric cancer patients, but the underlying mechanisms are poorly understood. Through a combination of in vivo screening and transcriptome profiling followed by qu...

    Shuang Li, Dongyang Guo, Qiang Sun, Lu Zhang, Yun Cui in Experimental & Molecular Medicine (2023)

  6. Article

    Open Access

    Skull metastasis is a poor prognostic factor for prostate cancer patients with bone metastasis: a retrospective study based on a Chinese population

    Skull is a relatively rare metastasis site for prostate cancer (PCa). There is no evidence regarding the prognostic indication of skull metastasis (SM) in PCa patients. In this study, we analyzed the prognosti...

    Tianyu **ong, Mingxin Jiang, **aobo Ye, Guangyi Zhu, Fang Cao, Yun Cui in BMC Urology (2023)

  7. Article

    Open Access

    RAGE inhibition alleviates lipopolysaccharides-induced lung injury via directly suppressing autophagic apoptosis of type II alveolar epithelial cells

    Advanced glycation end product receptor (RAGE) acts as a receptor of pro-inflammatory ligands and is highly expressed in alveolar epithelial cells (AECs). Autophagy in AECs has received much attention recently...

    ** **ong, Jiaying Dou, **gyi Shi, Yuqian Ren, Chunxia Wang in Respiratory Research (2023)

  8. Article

    Open Access

    The novel biomarkers for assessing clinical benefits of continuous renal replacement therapy in pediatric sepsis: a pilot study

    Continuous renal replacement therapy (CRRT) has been considered as an adjuvant therapy for sepsis. However, the novel biomarker to evaluate the benefits of CRRT is limited. The aim of this study was to explore...

    Yun Cui, Shuyun Feng, Huijie Miao, Tiantian Liu, **gyi Shi in Clinical Proteomics (2023)

  9. Article

    Open Access

    Upregulation of mir-1199-5p is associated with reduced type 2 5-α reductase expression in benign prostatic hyperplasia

    5-α reductase inhibitors (5-ARIs) are first-line drugs for managing benign prostatic hyperplasia (BPH). Unfortunately, some patients do not respond to 5-ARI therapy and may even show ...

    Zhanliang Liu, Zhemin Lin, Fang Cao, Mingxin Jiang, Song **, Yun Cui in BMC Urology (2022)

  10. Article

    Open Access

    Hospitalized patients with isolated distal deep vein thrombosis: anticoagulation therapy or not?

    Isolated distal deep vein thrombosis (IDDVT), a disease frequently detected in hospitalized patients, can progress to proximal deep vein thrombosis (PDVT) and pulmonary embolism (PE). Here, we evaluated the ef...

    **aolin Luo, Liying Zhang, Changchun Hou, Pengda Li, Shaofa Wu in Thrombosis Journal (2022)

  11. No Access

    Article

    Structure–texture decomposition-based dehazing of a single image with large sky area

    Traditional dehazing methods based on restoration are prone to color distortion and noise amplification when dealing with hazy image with large sky area. To improve dehazing effect, we propose a dehazing algor...

    Chaoying Tang, Ru Jia, Xue Ren, Yun Cui, Biao Wang in Machine Vision and Applications (2022)

  12. Article

    Open Access

    Estrogen and G protein-coupled estrogen receptor accelerate the progression of benign prostatic hyperplasia by inducing prostatic fibrosis

    Benign prostatic hyperplasia (BPH) is the most common and progressive urological disease in elderly men worldwide. Epidemiological studies have suggested that the speed of disease progression varies among indi...

    Yang Yang, **dong Sheng, Shuai Hu, Yun Cui, **g **ao, Wei Yu in Cell Death & Disease (2022)

  13. Article

    Open Access

    Extracorporeal membrane oxygenation for paediatric refractory hypoxic respiratory failure caused by adenovirus in Shanghai: a case series

    To assess the outcome of extracorporeal membrane oxygenation (ECMO) for severe adenovirus (Adv) pneumonia with refractory hypoxic respiratory failure (RHRF) in paediatric patients.

    Yun Cui, **gyi Shi, Yi** Zhou, Jiaying Dou, ** **ong, Ting Sun in BMC Pediatrics (2022)

  14. Article

    Open Access

    Fusobacterium nucleatum reduces METTL3-mediated m6A modification and contributes to colorectal cancer metastasis

    Microbiota-host interactions play critical roles in colorectal cancer (CRC) progression, however, the underlying mechanisms remain elusive. Here, we uncover that Fusobacterium nucleatum (F. nucleatum) induces a d...

    Shujie Chen,, Lu Zhang, Mengjie Li, Ying Zhang, Meng Sun in Nature Communications (2022)

  15. No Access

    Article

    The keratin 17/YAP/IL6 axis contributes to E-cadherin loss and aggressiveness of diffuse gastric cancer

    DGC is a particular aggressive malignancy with poor prognosis. Recent omics studies characterized DGC with CDH1/E-cadherin loss and EMT-signatures. However, the underlying mechanisms for maintaining the aggressiv...

    Mengjie Li, ** Rao, Yun Cui, Lu Zhang, **ang Li, Boya Wang, Yijun Zheng in Oncogene (2022)

  16. Article

    Retraction Note: Identification of a novel mutation of the COL2A1 gene in a Chinese family with spondyloepiphyseal dysplasia congenital

    Hongzhuo Li, Liang Ma, Baozhu Wang, Yun Cui, Tao **ao in European Spine Journal (2021)

  17. Article

    Therapeutic plasma exchange combined with continuous venovenous hemofiltration in a series of pediatric patients with toxic epidermal necrolysis

    Yun Cui, **gyi Shi, Chunxia Wang, Angela Vinturache in European Journal of Dermatology (2021)

  18. Article

    Open Access

    Multidrug resistant and extensively drug resistant Acinetobacter baumannii hospital infection associated with high mortality: a retrospective study in the pediatric intensive care unit

    Multidrug resistant (MDR) and extensively drug resistant (XDR) Acinetobacter baumannii presents challenges for clinical treatment and causes high mortality in children. We aimed to assess the risk factors and ove...

    **gyi Shi, Ting Sun, Yun Cui, Chunxia Wang, Fei Wang in BMC Infectious Diseases (2020)

  19. Article

    Open Access

    A case series of children with adenovirus pneumonia: three-year experiences in a tertiary PICU

    Describe the outcome of adenovirus pneumonia in a pediatric intensive care unit (PICU) over a 3-year period, to identify the risk factors that may be associated with worse outcome.

    **gyi Shi, Yi** Zhou, Fei Wang, Chunxia Wang, Huijie Miao, Ting Sun in BMC Pediatrics (2020)

  20. Article

    Open Access

    Impact of human papillomavirus infection in semen on sperm progressive motility in infertile men: a systematic review and meta-analysis

    Human papillomavirus (HPV) has been considered as one of the most common sexually transmitted viruses that may be linked to unexplained infertility in men. The possible mechanisms underlying correlation betwee...

    **aodan Cao, Renxiong Wei, **aoxia Zhang in Reproductive Biology and Endocrinology (2020)

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