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  1. Article

    Open Access

    The sequence and de novo assembly of the giant panda genome

    Using next-generation sequencing technology alone, we have successfully generated and assembled a draft sequence of the giant panda genome. The assembled contigs (2.25 gigabases (Gb)) cover approximately 94% o...

    Ruiqiang Li, Wei Fan, Geng Tian, Hongmei Zhu, Lin He, **g Cai, Quanfei Huang in Nature (2010)

  2. Article

    Erratum: The sequence and de novo assembly of the giant panda genome

    Nature 463, 311–317 (2010) In this Article, the Latin species name of the giant panda was written incorrectly as Ailuropoda melanoleura. The correct name is Ailuropoda melanoleuca.

    Ruiqiang Li, Wei Fan, Geng Tian, Hongmei Zhu, Lin He, **g Cai, Quanfei Huang in Nature (2010)

  3. No Access

    Article

    Ordered bilayer ruthenium–platinum core-shell nanoparticles as carbon monoxide-tolerant fuel cell catalysts

    Fabricating subnanometre-thick core-shell nanocatalysts is effective for obtaining high surface area of an active metal with tunable properties. The key to fully realize the potential of this approach is a rel...

    Yu-Chi Hsieh, Yu Zhang, Dong Su, Vyacheslav Volkov, Rui Si in Nature Communications (2013)

  4. Article

    Open Access

    Draft genome sequence of the mulberry tree Morus notabilis

    Human utilization of the mulberry–silkworm interaction started at least 5,000 years ago and greatly influenced world history through the Silk Road. Complementing the silkworm genome sequence, here we describe ...

    Ningjia He, Chi Zhang, **wu Qi, Shancen Zhao, Yong Tao in Nature Communications (2013)

  5. No Access

    Article

    Large enhancement in neurite outgrowth on a cell membrane-mimicking conducting polymer

    Although electrically stimulated neurite outgrowth on bioelectronic devices is a promising means of nerve regeneration, immunogenic scar formation can insulate electrodes from targeted cells and tissues, there...

    Bo Zhu, Shyh-Chyang Luo, Haichao Zhao, Hsing-An Lin, Jun Sekine in Nature Communications (2014)

  6. No Access

    Article

    Benzene construction via organocatalytic formal [3+3] cycloaddition reaction

    The benzene unit, in its substituted forms, is a most common scaffold in natural products, bioactive molecules and polymer materials. Nearly 80% of the 200 best selling small molecule drugs contain at least on...

    Tingshun Zhu, Pengcheng Zheng, Chengli Mou, Song Yang, Bao-An Song in Nature Communications (2014)

  7. Article

    Open Access

    The draft genome of the large yellow croaker reveals well-developed innate immunity

    The large yellow croaker, Larimichthys crocea, is one of the most economically important marine fish species endemic to China. Its wild stocks have severely suffered from overfishing, and the aquacultured species...

    Changwen Wu, Di Zhang, Mengyuan Kan, Zhengmin Lv, Aiyi Zhu in Nature Communications (2014)

  8. No Access

    Article

    Whole-exome sequencing implicates UBE3D in age-related macular degeneration in East Asian populations

    Age-related macular degeneration (AMD) is a leading cause of irreversible central blindness among the elderly worldwide. We use exome sequencing to analyse nonsynonymous single-nucleotide variants (SNVs) acros...

    Lv-Zhen Huang, Ying-Jie Li, Xue-Feng **e, **g-**g Zhang in Nature Communications (2015)

  9. Article

    Open Access

    Predicting and verifying outcome of Tripterygium wilfordii Hook F. based therapy in rheumatoid arthritis: from open to double-blinded randomized trial

    Tripterygium wilfordii Hook F. (TwHF) based therapy has been proved as effective in treating rheumatoid arthritis (RA), yet the predictors to its response remains unclear. A two-stage trial was designed to identi...

    Miao Jiang, Qinglin Zha, Chi Zhang, Cheng Lu, ** Yan in Scientific Reports (2015)

  10. Article

    Open Access

    An integrated system for identifying the hidden assassins in traditional medicines containing aristolochic acids

    Traditional herbal medicines adulterated and contaminated with plant materials from the Aristolochiaceae family, which contain aristolochic acids (AAs), cause aristolochic acid nephropathy. Approximately 256 t...

    Lan Wu, Wei Sun, Bo Wang, Haiyu Zhao, Yaoli Li, Shaoqing Cai in Scientific Reports (2015)

  11. No Access

    Article

    Linc-YY1 promotes myogenic differentiation and muscle regeneration through an interaction with the transcription factor YY1

    Little is known how lincRNAs are involved in skeletal myogenesis. Here we describe the discovery of Linc-YY1 from the promoter of the transcription factor (TF) Yin Yang 1 (YY1) gene. We demonstrate that Linc-YY1 ...

    Liang Zhou, Kun Sun, Yu Zhao, Suyang Zhang, Xuecong Wang in Nature Communications (2015)

  12. Article

    Open Access

    Blood lead level and its association with body mass index and obesity in China - Results from SPECT-China study

    We aimed to report environmental and blood lead level (BLL) in China and investigate the relationship of BLL with body mass index (BMI) and obesity. 5558 subjects were enrolled from 16 sites in China. BLL was ...

    Ningjian Wang, Chi Chen, **aomin Nie, Bing Han, Qin Li, Yi Chen in Scientific Reports (2015)

  13. Article

    Open Access

    Dihydroartemisinin prevents breast cancer-induced osteolysis via inhibiting both breast caner cells and osteoclasts

    Bone is the most common site of distant relapse in breast cancer, leading to severe complications which dramatically affect the patients’ quality of life. It is believed that the crosstalk between metastatic b...

    Ming-Xuan Feng, Jian-**n Hong, Qiang Wang, Yong-Yong Fan in Scientific Reports (2016)

  14. Article

    Y-chromosomes from skeletal remains of Chinese Expeditionary Force offer a clue to their paternal relatives

    Shao-Qing Wen, **n-Zhu Tong, Chi-Zao Wang, Pan-**n Du, **-Yi Wang in Science Bulletin (2016)

  15. Article

    Open Access

    Identification of Liver Epithelial Cell-derived Ig Expression in μ chain-deficient mice

    Growing evidence indicates that B cells are not the only source of immunoglobulin (Ig). To investigate this discovery further, we used μMT mice, which have a disruption of the first transmembrane exon of the μ...

    Wenwei Shao, Chi Zhang, Enyang Liu, Long Zhang, Junfan Ma, Zhu Zhu in Scientific Reports (2016)

  16. Article

    Open Access

    Metabolomics reveals the mechanisms for the cardiotoxicity of Pinelliae Rhizoma and the toxicity-reducing effect of processing

    Pinelliae Rhizoma (PR) is a commonly used Chinese medicinal herb, but it has been frequently reported about its toxicity. According to the traditional Chinese medicine theory, processing can reduce the toxicit...

    Tao Su, Yong Tan, Man-Shan Tsui, Hua Yi, **u-Qiong Fu, Ting Li in Scientific Reports (2016)

  17. No Access

    Article

    Integrin-YAP/TAZ-JNK cascade mediates atheroprotective effect of unidirectional shear flow

    YAP and TAZ, effectors of the Hippo pathway, sense mechanical forces generated by blood flow and play a role in atherosclerosis pathogenesis.

    Li Wang, Jiang-Yun Luo, Bochuan Li, **ao Yu Tian, Li-**g Chen, Yuhong Huang in Nature (2016)

  18. Article

    Open Access

    A Mott insulator continuously connected to iron pnictide superconductors

    Iron-based superconductivity develops near an antiferromagnetic order and out of a bad-metal normal state, which has been interpreted as originating from a proximate Mott transition. Whether an actual Mott ins...

    Yu Song, Zahra Yamani, Chongde Cao, Yu Li, Chenglin Zhang in Nature Communications (2016)

  19. Article

    Open Access

    Overcoming sorafenib evasion in hepatocellular carcinoma using CXCR4-targeted nanoparticles to co-deliver MEK-inhibitors

    Sorafenib is a RAF inhibitor approved for several cancers, including hepatocellular carcinoma (HCC). Inhibition of RAF kinases can induce a dose-dependent “paradoxical” upregulation of the downstream mitogen-a...

    Yunching Chen, Ya-Chi Liu, Yun-Chieh Sung, Rakesh R. Ramjiawan in Scientific Reports (2017)

  20. Article

    Open Access

    Cadmium exposure and its association with serum uric acid and hyperuricemia

    Few studies have investigated the association between serum uric acid (UA) and cadmium exposure. Our previous study revealed a significantly higher blood cadmium (CdB) level in the Chinese population compared ...

    Honglin Sun, Ningjian Wang, Chi Chen, **aomin Nie, Bing Han, Qin Li in Scientific Reports (2017)

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