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  1. No Access

    Chapter and Conference Paper

    Combining a High-Throughput Bioinformatics Grid and Bioinformatics Web Services

    We have created a high-throughput grid for biological sequence analysis, which is freely accessible via bioinformatics Web services. The system allows the execution of computationally intensive sequence alignm...

    Chunyan Wang, Paul M. K. Gordon in Distributed, High-Performance and Grid Com… (2007)

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    Chapter and Conference Paper

    Instance Discovery and Schema Matching with Applications to Biological Deep Web Data Integration

    This paper presents data mining-based techniques for enabling data integration across deep web data sources. We target query processing across inter-dependent data sources. Thus, besides input-input and output...

    Tantan Liu, Fan Wang, Gagan Agrawal in Data Integration in the Life Sciences (2010)

  3. No Access

    Chapter and Conference Paper

    High-Performance Systems for in Silico Microscopy Imaging Studies

    High-resolution medical images from advanced instruments provide rich information about morphological and functional characteristics of biological systems. However, most of the information available in biomedi...

    Fusheng Wang, Tahsin Kurc, Patrick Widener in Data Integration in the Life Sciences (2010)

  4. No Access

    Chapter and Conference Paper

    Deep Convolutional Neural Networks with Residual Blocks for Wafer Map Defect Pattern Recognition

    Different deep convolution neural network (DCNN) models have been proposed for wafer map pattern identification and classification tasks in previous studies. However, factors such as the effect of input image ...

    Zemenu Endalamaw Amogne, Fu-Kwun Wang in Advances in Computational Intelligence (2021)

  5. No Access

    Chapter and Conference Paper

    ARGLRR: An Adjusted Random Walk Graph Regularization Sparse Low-Rank Representation Method for Single-Cell RNA-Sequencing Data Clustering

    Researchers may now explore biological concerns at the cell level because of the advancement of single-cell transcriptome sequencing technologies. One of the primary applications of single-cell RNA-seq (scRNA-...

    Zhen-Chang Wang, **-**ng Liu, Jun-Liang Shang in Bioinformatics Research and Applications (2022)

  6. No Access

    Chapter and Conference Paper

    MLMVFE: A Machine Learning Approach Based on Muli-view Features Extraction for Drug-Disease Associations Prediction

    Determining the associations between drugs and diseases plays an important role in the drugs development processes. However, current drug-disease associations (DDAs) prediction methods are too homogeneous for ...

    Ying Wang, Ying-Lian Gao, Juan Wang in Bioinformatics Research and Applications (2022)

  7. No Access

    Chapter and Conference Paper

    GNN-Dom: An Unsupervised Method for Protein Domain Partition via Protein Contact Map

    Protein domains are the basic building blocks of protein structures, which fold and function independently. Protein domain partition could be used as measure to decompose the modeling of a large, multi-domain ...

    Lei Wang, Yan Wang in Bioinformatics Research and Applications (2022)

  8. Chapter and Conference Paper

    Correction to: Simulating Spiking Neural Networks Based on SW26010pro

    Zhichao Wang, Xuelei Li, **tao Meng, Yi Pan in Bioinformatics Research and Applications (2022)

  9. No Access

    Chapter and Conference Paper

    Automatic ICD Coding Based on Multi-granularity Feature Fusion

    International Classification of Disease (ICD) coding is to assign standard codes, which describe the state of a patient, to a clinical note. It is challenging given the complexity and the number of codes. The ...

    Ying Yu, Junwen Duan, Han Jiang, Jianxin Wang in Bioinformatics Research and Applications (2022)

  10. No Access

    Chapter and Conference Paper

    NIDN: Medical Code Assignment via Note-Code Interaction Denoising Network

    Clinical records are files that contain detailed information about a patient's health status. Clinical notes are typically complex, and the medical code space is large, so medical code assignment from clinical...

    **aobo Li, Yijia Zhang, **ngwang Li, Jian Wang in Bioinformatics Research and Applications (2022)

  11. No Access

    Chapter and Conference Paper

    TDCOSR: A Multimodality Fusion Framework for Association Analysis Between Genes and ROIs of Alzheimer’s Disease

    The complementary multimodality data fusion analysis provides a new perspective for revealing associations between genes and brain regions of interests (ROIs) of Alzheimer’s disease (AD). In this paper, we pro...

    Qi Zou, Yan Sun, Feng Li, Juan Wang in Bioinformatics Research and Applications (2022)

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    Chapter and Conference Paper

    A Multimodal Data Fusion-Based Deep Learning Approach for Drug-Drug Interaction Prediction

    Prediction of drug-drug interaction (DDI) is one of the vital topics in drug development. Many computational methods have been present for DDI prediction. However, these methods are often limited to exploiting...

    An Huang, **aolan **e, **aoqi Wang in Bioinformatics Research and Applications (2022)

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    Chapter and Conference Paper

    Prediction of Drug-Disease Relationship on Heterogeneous Networks Based on Graph Convolution

    Drug-disease association prediction is essential in drug development and repositioning. At present, the proposed drug-disease association prediction models based on graph convolution usually learn the characte...

    Jiancheng Zhong, Pan Cui, Zuohang Qu in Bioinformatics Research and Applications (2022)

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    Chapter and Conference Paper

    Fusing Label Relations for Chinese EMR Named Entity Recognition with Machine Reading Comprehension

    Chinese electronic medical records named entity recognition (NER) is a core task in medical knowledge mining, which is usually viewed as a sequence labeling problem. Recent works introduce the machine reading ...

    Shuyue Liu, Junwen Duan, Feng Gong, Hailin Yue in Bioinformatics Research and Applications (2022)

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    Chapter and Conference Paper

    MPCDDI: A Secure Multiparty Computation-Based Deep Learning Framework for Drug-Drug Interaction Predictions

    Drug-drug interaction (DDI) is a key concern in drug development and pharmacovigilance. It is important to improve DDI predictions by integrating multi-source data from various pharmaceutical companies. Unfort...

    **a **ao, **aoqi Wang, Shengyun Liu in Bioinformatics Research and Applications (2022)

  16. No Access

    Chapter and Conference Paper

    Simulating Spiking Neural Networks Based on SW26010pro

    The spiking neural network (SNN) simulators play a significant role in modeling neural systems and the study of brain function. Currently, many simulators using CPU or GPU have been developed. However, these s...

    Zhichao Wang, Xuelei Li, **tao Meng, Yi Pan in Bioinformatics Research and Applications (2022)

  17. No Access

    Chapter and Conference Paper

    Microanatomy of Left Bundle Branch in Chinese Adult Hearts: Aiming to the Research on Morphological Information

    Background: The left bundle branch (LBB) in human heart is very thin and certainly individually different, so the corresponding anatomical data is relatively rare. The gradual spread of His-Purkinje system pac...

    Yangyun Lou, Ting Li, Kaili Wang, Zheyi Gong in Biomedical and Computational Biology (2023)

  18. No Access

    Chapter and Conference Paper

    Arabinogalactan Prevented APAP-Induced Acute Liver Injury by Regulating the Intestinal Flora in Mice

    Background: This study aimed to explore the mechanism by which arabinogalactan (AG) inhibited N-acetyl-para-aminophenol (APAP)-induced acute liver injury in mice. The balance of the mouse intestinal flora and ...

    Dongxu Jiang, Dahui Zhang, Shengxue Zhou in Biomedical and Computational Biology (2023)

  19. No Access

    Chapter and Conference Paper

    Physiological Polyphosphate: A New Molecular Paradigm in Biomedical and Biocomputational Applications for Human Therapy

    Inorganic polyphosphates (polyP) consist of linear chains of orthophosphate units linked together by high-energy phosphoanhydride bonds. The family of polyP molecules are evolutionarily old biopolymers and fou...

    Werner E. G. Müller, Shunfeng Wang in Bioinformatics and Biomedical Engineering (2023)

  20. No Access

    Chapter and Conference Paper

    CHLPCA: Correntropy-Based Hypergraph Regularized Sparse PCA for Single-Cell Type Identification

    Over the past decade, high-throughput sequencing technologies have driven a dramatic increase in single-cell RNA sequencing (scRNA-seq) data. The study of scRNA-seq data has widened the scope and depth of rese...

    Tai-Ge Wang, **ang-Zhen Kong, Sheng-Jun Li in Bioinformatics Research and Applications (2023)

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