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Chapter
Measurement of Cytochrome Oxidase Redox State by Near Infrared Spectroscopy
Although near infrared spectroscopy (NIRS) is primarily used to probe changes in oxyhaemoglobin (HbO2) and deoxyhaemoglobin (dHb) concentrations, it has long been realised that there is a significant oxygen-conce...
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Chapter
NMR Studies of Hypoxic-Ischaemic Injury in Neonatal Brain Using Imaging and Spectroscopy
Brain injury arising in the perinatal period leads to death or permanent and severe impairment in more than 1000 infants per year in the UK (Alberman and Botting, 1991). The aim of this work is to use nuclear ...
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Chapter
Correlation between Absolute Deoxyhaemoglobin [dHb] Measured by Near Infrared Spectroscopy (NIRS) and Absolute R2′ as Determined by Magnetic Resonance Imaging (MRI)
Magnetic Resonance Imaging (MRI) is a technique which provides high spatial resolution combined with a wide range of image contrast mechanisms. Standard MR image contrast relies upon tissue differences in MR v...