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Chapter
Transmembrane Currents in Capillary Endothelial Cells are Modulated by External Mg2+ Ions
The capillary endothelium of the brain is involved essentially in the preservation of the blood-brain barrier and in the regulation of brain microcirculation. As a biological membrane lining the inner wall of ...
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Chapter
Metabolic Inhibitors Affect the Conductance of Low Voltage-Activated Calcium Channels in Brain Capillary Endothelial Cells
The brain capillary endothelium plays an essential role in the preservation of the blood-brain barrier and in the control of blood microcirculation. Since hypoxia (Po2: 20 Torr) increases K+ conductance in brain ...
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Chapter
Evidence for Glucose Uptake in the Rabbit Carotid Body
The carotid body located in the bifurcation of the carotid arteries is able to detect gas changes in blood composition (PO2, PCO2/pH) and to transduce them into afferent nerve signal. The intimate mechanism respo...
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Chapter
Does an Inward-Rectifying K Channel Regulate Type-I Cell Response to Hypoxia?
Type-I cells (from rabbit embryos) in primary cell culture were studied using the patch-clamp technique on the cell-attached configuration. Cells exhibited resting potentials of about -40 mV under normoxia. In...
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Chapter
Aerobic Glycolysis in the Retina of the Crab Ocypode Ryderi
Higher crustaceans (Malacostracan) possess compound eyes of a similar type as insects (apposition eyes). They consist of several thousands of ommatidia, each composed of a cornea followed by the dioptric appar...
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Chapter and Conference Paper
Ionic Currents in Carotid Body Type I Cells and the Effects of Hypoxia and NaCN
Whole-cell currents of type I cells were characterized using the patch-clamp technique. At least four types of currents could be separated: 1) outward rectifying currents, which were sensitive to Cs+ and tetraeth...
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Chapter
Possible Meaning of Different Ionic Changes in the Carotid Body During Hypoxia
It is well known that the carotid body, a peripheral chemoreceptor located near the carotid sinus, is able to detect gas changes (PO2, PCO2/pH) in arterial blood composition and transduce them into nerve signals ...
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Chapter
O2 Chemoreception of the Cat Carotid Body in vitro
Since the fundamental research of de Castro (1926) and of Heymans and Bouckaert (1930), the carotid body has been considered to be a peripheral chemoreceptor which transduces changes in arterial Po2 and arterial ...